Patents by Inventor Julien Pierron

Julien Pierron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the hydrogenation of ketoesters
    Patent number: 8431741
    Abstract: The invention relaters to a process for the production of an (S)- or (R)-4-halo-3-hydroxybutyrate, comprising reacting a 4-haloacetoacetate with hydrogen in the presence of a solvent, the solvent being a solvent mixture, which comprises a first solvent and a second solvent, wherein the first solvent is an aliphatic alcohol, preferably methanol, ethanol or propanol, and the second solvent is aprotic and comprises at least one oxygen atom; and a catalyst of the formula [RuXYZ]X, wherein X is halogen, preferably Cl or Br, or OAc, acetoacetate, allyl or ClO4, Y is a bidentate organic ligand having two phosphine groups, and Z is an arene, preferably cymene, benzene, xylene or toluene, or a polyene, preferably a diene, or an alkene.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: April 30, 2013
    Assignee: Lonza Ltd
    Inventors: Dario Veghini, Markus Bicker, Miguel Angel Caraucán Dávila, Golo Heckmann, Thomas Ward, Christophe Malan, Julien Pierron, Antonio Zanotti-Gerosa, Hans Nedden, Laleh Jafarpour
  • PROCESS FOR THE HYDROGENATION OF KETOESTERS
    Publication number: 20120016153
    Abstract: The invention relaters to a process for the production of an (S)- or (R)-4-halo-3-hydroxybutyrate, comprising reacting a 4-haloacetoacetate with hydrogen in the presence of a solvent, the solvent being a solvent mixture, which comprises a first solvent and a second solvent, wherein the first solvent is an aliphatic alcohol, preferably methanol, ethanol or propanol, and the second solvent is aprotic and comprises at least one oxygen atom; and a catalyst of the formula [RuXYZ]X, wherein X is halogen, preferably Cl or Br, or OAc, acetoacetate, allyl or ClO4, Y is a bidentate organic ligand having two phosphine groups, and Z is an arene, preferably cymene, benzene, xylene or toluene, or a polyene, preferably a diene, or an alkene.
    Type: Application
    Filed: May 10, 2011
    Publication date: January 19, 2012
    Inventors: Dario Veghini, Markus Bicker, Miguel Angel Caraucán Dávila, Golo Heckmann, Thomas Ward, Christophe Malan, Julien Pierron, Antonio Zanotti-Gerosa, Hans Nedden, Laleh Jafarpour