Patents by Inventor Julien Textoris
Julien Textoris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240417799Abstract: A method for determining in vitro or ex vivo the immune status of an individual, preferably a patient, including a step of detecting and/or quantifying the expression of one or more HERV/MaLR sequences in a biological sample of the individual. Also relates to the tools for implementing the method and to the uses thereof.Type: ApplicationFiled: July 15, 2024Publication date: December 19, 2024Applicant: BIOMERIEUXInventors: Marine MOMMERT, Olivier TABONE, Julien TEXTORIS, François MALLET
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Patent number: 12110556Abstract: A kit for in vitro measurement of a at least one IL7R gene transcript in a blood sample, including specific reagents for measuring the transcript, and a control sample calibrated to contain the IL7R gene transcript corresponding to the mean quantity measured in a pool of reference blood samples from human patients in a state of septic shock when reference blood samples are taken, or who were in a state of septic shock within 72 h after taking the reference blood samples, and who were known to have survived, and/or a calibrated to contain the quantity of an IL7R gene transcript corresponding to the mean quantity measured in reference blood samples from patients in a state of septic shock when the reference blood samples are taken, or who were in a state of septic shock within 72 h after taking the reference blood samples, and not to have survived.Type: GrantFiled: April 26, 2022Date of Patent: October 8, 2024Assignees: BIOMERIEUX, HOSPICES CIVILS DE LYON, UNIVERSITE CLAUDE BERNARDInventors: Elisabeth Cerrato, Benjamin Delwarde, Guillaume Monneret, Estelle Peronnet, Julien Textoris, Fabienne Venet
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Patent number: 12071670Abstract: A method for determining in vitro or ex vivo the immune status of an individual, preferably a patient, including a step of detecting and/or quantifying the expression of one or more HERV/MaLR sequences in a biological sample of the individual. Also relates to the tools for implementing the method and to the uses thereof.Type: GrantFiled: June 28, 2019Date of Patent: August 27, 2024Assignee: BIOMÉRIEUXInventors: Marine Mommert, Olivier Tabone, Julien Textoris, François Mallet
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Publication number: 20240247312Abstract: An in vitro or ex vivo method for determining the risk of incidence of a healthcare-associated infection in a patient, including a step of measuring the expression of at least one gene encoding a pro-inflammatory cytokine receptor located on chromosome 2 in the region 2q11-2q12, in a biological sample from the patient.Type: ApplicationFiled: July 5, 2021Publication date: July 25, 2024Applicants: BIOMÉRIEUX, BIOASTERInventors: Laurence VACHOT, François MALLET, Guillaume MONNERET, Virginie MOUCADEL, Alexandre PACHOT, Estelle PERONNET, Thomas RIMMELÉ, Julien TEXTORIS, Fabienne VENET
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Publication number: 20230313326Abstract: An in vitro or ex vivo method for determining the risk of complication in a patient, including a step of measuring the expression of C3AR1 in a biological sample from the patient.Type: ApplicationFiled: July 5, 2021Publication date: October 5, 2023Applicants: BIOMÉRIEUX, BIOASTERInventors: Laurence VACHOT, François MALLET, Guillaume MONNERET, Virginie MOUCADEL, Alexandre PACHOT, Estelle PERONNET, Thomas RIMMELÉ, Julien TEXTORIS, Fabienne VENET
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Publication number: 20230279492Abstract: The invention relates to an in vitro or ex vivo method for determining the risk of incidence of a care-related infection in a patient, including a step of measuring the expression of CIITA in a biological sample from said patient.Type: ApplicationFiled: July 5, 2021Publication date: September 7, 2023Applicants: BIOMÉRIEUX, BIOASTERInventors: Laurence VACHOT, François MALLET, Guillaume MONNERET, Virginie MOUCADEL, Alexandre PACHOT, Estelle PERONNET, Thomas RIMMELÉ, Julien TEXTORIS, Fabienne VENET
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Publication number: 20230250479Abstract: An in vitro or ex vivo method for determining the risk of incidence of a care-related infection includes a step of measuring the expression of CD177 in a biological sample from said patient.Type: ApplicationFiled: July 5, 2021Publication date: August 10, 2023Applicants: BIOMÉRIEUX, BIOASTERInventors: Laurence VACHOT, François MALLET, Guillaume MONNERET, Virginie MOUCADEL, Alexandre PACHOT, Estelle PERONNET, Thomas RIMMELÉ, Julien TEXTORIS, Fabienne VENET
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Publication number: 20230220477Abstract: An in vitro or ex vivo method for determining the risk of incidence of a healthcare-associated infection includes a step of measuring the expression of TAP2 in a biological sample from said patient.Type: ApplicationFiled: July 5, 2021Publication date: July 13, 2023Applicants: BIOMÉRIEUX, BIOASTERInventors: Laurence VACHOT, François MALLET, Guillaume MONNERET, Virginie MOUCADEL, Alexandre PACHOT, Estelle PERONNET, Thomas RIMMELÉ, Julien TEXTORIS, Fabienne VENET
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Publication number: 20230194549Abstract: An in vitro or ex vivo method, based on the measurement of the expression of cytokine(s), from a patient's blood sample, incubated with a stimulus, for determining the risk of occurrence of a healthcare-associated infection in the patient, within seven days following the day on which the collection of the biological sample has been performed from the patient.Type: ApplicationFiled: April 8, 2021Publication date: June 22, 2023Applicants: BIOMÉRIEUX, BIOASTER, HOSPICES CIVILS DE LYONInventors: François MALLET, Guillaume MONNERET, Virginie MOUCADEL, Alexandre PACHOT, Estelle PERONNET, Julien TEXTORIS, Fabienne VENET, Thomas RIMMELÉ
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Publication number: 20220333201Abstract: An in vitro or ex vivo method for determining the risk of occurrence of a healthcare-associated infection in a patient, including a step of measuring the expression of CX3CR1, in a biological sample of said patient.Type: ApplicationFiled: September 25, 2020Publication date: October 20, 2022Applicants: BIOMÉRIEUX, BIOASTER, HOSPICES CIVILS DE LYONInventors: Laurence VACHOT, François MALLET, Guillaume MONNERET, Virginie MOUCADEL, Alexandre PACHOT, Estelle PERONNET, Thomas RIMMELÉ, Julien TEXTORIS, Fabienne VENET
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Publication number: 20220296606Abstract: The present invention relates to a pharmaceutical or veterinary composition for the use thereof in preventing and/or treating infection by the influenza viruses. The composition is characterized in that it contains, in an appropriate pharmaceutical carrier, at least one compound selected from among Etilefrine and Diltiazem.Type: ApplicationFiled: May 31, 2022Publication date: September 22, 2022Inventors: Manuel ROSA-CALATRAVA, Olivier TERRIER, Julien TEXTORIS, Guy BOIVIN, Mario PIZZORNO
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Publication number: 20220259661Abstract: A kit for in vitro measurement of a at least one IL7R gene transcript in a blood sample, including specific reagents for measuring the transcript, and a control sample calibrated to contain the IL7R gene transcript corresponding to the mean quantity measured in a pool of reference blood samples from human patients in a state of septic shock when reference blood samples are taken, or who were in a state of septic shock within 72 h after taking the reference blood samples, and who were known to have survived, and/or a calibrated to contain the quantity of an IL7R gene transcript corresponding to the mean quantity measured in reference blood samples from patients in a state of septic shock when the reference blood samples are taken, or who were in a state of septic shock within 72 h after taking the reference blood samples, and not to have survived.Type: ApplicationFiled: April 26, 2022Publication date: August 18, 2022Applicants: BIOMERIEUX, HOSPICES CIVILS DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1Inventors: Elisabeth CERRATO, Benjamin DELWARDE, Guillaume MONNERET, Estelle PERONNET, Julien TEXTORIS, Fabienne VENET
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Patent number: 11351180Abstract: The present invention relates to a pharmaceutical or veterinary composition for the use thereof in preventing and/or treating infection by the influenza viruses. Said composition is characterized in that it contains, in an appropriate pharmaceutical carrier, at least one compound selected from among Etilefrine and Diltiazem.Type: GrantFiled: March 18, 2016Date of Patent: June 7, 2022Assignees: UNIVERSITE CLAUDE BERNARD LYON 1, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), HOSPICES CIVILS DE LYON, UNIVERSITE LAVALInventors: Manuel Rosa-Calatrava, Olivier Terrier, Julien Textoris, Guy Boivin, Mario Pizzorno
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Patent number: 11339438Abstract: The invention concerns a method of in vitro or ex vivo evaluation of the risk of complications in a patient who has sustained an insult or an infection generating a systemic inflammatory response syndrome, the method being characterized in that it comprises the step of detecting, in a biological sample obtained from said patient, at least one transcript of the IL7R gene, as well as measuring, in vitro or ex vivo, the quantity of at least one transcript of the IL7R gene, in a biological sample from a patient who has sustained an insult or an infection generating a systemic inflammatory response syndrome, in order to evaluate the risk of complications, and in particular of mortality, in said patient. The invention also concerns kits for measuring, in vitro or ex vivo, the quantity of at least one transcript of the IL7R gene in a biological sample.Type: GrantFiled: December 1, 2016Date of Patent: May 24, 2022Assignees: BIOMERIEUX, HOSPICES CIVILS DE LYON, UNIVERSITE CLAUDE BENARD LYON 1Inventors: Elisabeth Cerrato, Benjamin Delwarde, Guillaume Monneret, Estelle Peronnet, Julien Textoris, Fabienne Venet
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Publication number: 20210254165Abstract: A method for determining in vitro or ex vivo the immune status of an individual, preferably a patient, including a step of detecting and/or quantifying the expression of one or more HERV/MaLR sequences in a biological sample of the individual. Also relates to the tools for implementing the method and to the uses thereof.Type: ApplicationFiled: June 28, 2019Publication date: August 19, 2021Applicants: BIOMÉRIEUX, BIOASTER, HOSPICES CIVILS DE LYONInventors: Marine MOMMERT, Olivier TABONE, Julien TEXTORIS, François MALLET
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Publication number: 20190017118Abstract: The invention concerns a method of in vitro or ex vivo evaluation of the risk of complications in a patient who has sustained an insult or an infection generating a systemic inflammatory response syndrome, the method being characterized in that it comprises the step of detecting, in a biological sample obtained from said patient, at least one transcript of the IL7R gene, as well as measuring, in vitro or ex vivo, the quantity of at least one transcript of the IL7R gene, in a biological sample from a patient who has sustained an insult or an infection generating a systemic inflammatory response syndrome, in order to evaluate the risk of complications, and in particular of mortality, in said patient. The invention also concerns kits for measuring, in vitro or ex vivo, the quantity of at least one transcript of the IL7R gene in a biological sample.Type: ApplicationFiled: December 1, 2016Publication date: January 17, 2019Applicants: BIOMERIEUX, HOSPICES CMLS DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1Inventors: Elisabeth CERRATO, Benjamin DELWARDE, Guillaume MONNERET, Estelle PERONNET, Julien TEXTORIS, Fabienne VENET
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Publication number: 20180042937Abstract: The present invention relates to a pharmaceutical or veterinary composition for the use thereof in preventing and/or treating infection by the influenza viruses. Said composition is characterized in that it contains, in an appropriate pharmaceutical carrier, at least one compound selected from among Etilefrine and Diltiazem.Type: ApplicationFiled: March 18, 2016Publication date: February 15, 2018Inventors: Manuel ROSA-CALATRAVA, Olivier TERRIER, Julien TEXTORIS, Guy BOIVIN, Mario PIZZORNO
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Patent number: 9433592Abstract: Pharmaceutical or veterinary compositions to prevent or treat viral infections, in particular to prevent or treat influenza A, B and C virus infections.Type: GrantFiled: December 7, 2010Date of Patent: September 6, 2016Assignees: UNIVERSITE CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), HOSPICES CIVILS DE LYONInventors: Manuel Rosa-Calatrava, Jean-Jacques Diaz, Julien Textoris, Laurence Josset
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Publication number: 20130012502Abstract: Pharmaceutical or veterinary compositions to prevent or treat viral infections, in particular to prevent or treat influenza A, B and C virus infections.Type: ApplicationFiled: December 7, 2010Publication date: January 10, 2013Applicants: HOSPICES CIVILS DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1Inventors: Manuel Rosa-Calatrava, Jean-Jacques Diaz, Julien Textoris, Laurence Josset