Patents by Inventor Juliesta E. Sylvester

Juliesta E. Sylvester has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified template-independent enzymes for polydeoxynucleotide synthesis
    Patent number: 10059929
    Abstract: The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3?-O-blocking moieties to a nucleic acid initiator, without the use of a template. The invention further includes the identified polymerases, and methods of using the polymerases for de novo synthesis of predetermined oligonucleotide sequences.
    Type: Grant
    Filed: October 20, 2015
    Date of Patent: August 28, 2018
    Assignee: Molecular Assemblies, Inc.
    Inventors: J. William Efcavitch, Juliesta E. Sylvester
  • MODIFIED TEMPLATE-INDEPENDENT ENZYMES FOR POLYDEOXYNUCLEOTIDE SYNTHESIS
    Publication number: 20160108382
    Abstract: The invention includes methods for identifying polymerases, such as modified terminal nucleotidyl transferases (TdT), that are capable of binding nucleotides comprising removable 3?-O-blocking moieties to a nucleic acid initiator, without the use of a template. The invention further includes the identified polymerases, and methods of using the polymerases for de novo synthesis of predetermined oligonucleotide sequences.
    Type: Application
    Filed: October 20, 2015
    Publication date: April 21, 2016
    Inventors: J. William Efcavitch, Juliesta E. Sylvester