Patents by Inventor Julio Cesar Francisco RUIZ

Julio Cesar Francisco RUIZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIF-2? inhibitors for treating iron overload disorders
    Patent number: 10098878
    Abstract: The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating iron overload disorders. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and reduced liver iron accumulation and serum iron parameters in both prophylactic and treatment mouse models.
    Type: Grant
    Filed: September 25, 2015
    Date of Patent: October 16, 2018
    Assignee: The Board of Regents of the University of Texas System
    Inventors: Richard Keith Bruick, Yaomin Chen, Julio Cesar Francisco Ruiz
  • HIF-2alpha INHIBITORS FOR TREATING IRON OVERLOAD DISORDERS
    Publication number: 20170304300
    Abstract: The present disclosure relates to HIF-2? inhibitors and methods of making and using them for treating iron overload disorders. Certain compounds were potent in HIF-2? scintillation proximity assay, luciferase assay, and VEGF ELISA assay, and reduced liver iron accumulation and serum iron parameters in both prophylactic and treatment mouse models.
    Type: Application
    Filed: September 25, 2015
    Publication date: October 26, 2017
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Richard Keith BRUICK, Yaomin CHEN, Julio Cesar Francisco RUIZ