Abstract: An assay card and devices and methods for isolating chambers on the assay card are described. The assay card comprises a substrate formed of one or more materials, e.g., plastic, having a softening temperature, the substrate defining channels communicating with respective reaction chambers. The assay card may be heated in a region of the channels to at least the softening temperature. The softened plastic may be deformed, e.g., with a tool which may or may not also provide the heat for softening the substrate. In this manner, the plastic of the substrate may be caused to at least partially obstruct the channels, thereby isolating the reaction chambers. The invention also relates to a method of manufacturing a tool device that includes pins for heating and deforming an assay card.

Abstract: The present application relates to an apparatus and method for non-contact collapsing of a porous material on a nonporous substrate.

Abstract: A process and apparatus for producing a thick foam from a spray of liquid and air. An interrupter is located in the path of a controlled portion of the outer periphery of a continuous stream of liquid. By precisely controlling the amount of peripheral flow impinged upon by the interrupter in the stream periphery, turbulence is created with consequent pressure drop and ingress of counter flowing ambient air which mixes with and causes foaming of the liquid constituent. The apparatus produces relatively large liquid particulate in air suspension. Such particulate is not readily inhaled or sensed by olfactory faculties. The dense, low velocity foaming spray which is produced adheres to target surfaces and remains in suspension eliminating dripping or running liquid.