Patents by Inventor Julio Palacio

Julio Palacio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10457747
    Abstract: Provided is a method for obtaining high-yield, stable expression cell clones from myeloma cell lines in a protein-free culture medium. The method is used for industrial production of a recombinant antibody, and includes three stage: (1) adapting to a protein-free culture medium, statically culturing cells at a low density, and gradually reducing a fat-rich supplement to a chemical culture medium; (2) adapting to a protein-free culture medium; culturing cells at a high density, and using a perfusion fermentation system in a laboratory scale; and (3) screening high-yield, stable expression cell clones from the cells after fermentation ends. The cell clone may be used to produce a humanized anti-NeuGcGM3 14F7 recombinant antibody.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: October 29, 2019
    Assignees: BIOTECH PHARMACEUTICAL CO. LTD., CENTRO DE INMUNOLOGIA MOLECULAR
    Inventors: MeyLen Chea, Julio Palacios, Miguel Arias, Loany Calvo, Tamara González, Rolando Pérez, Zhi Bai, Yuemao Liu, Kaiheng Xiao, Xiao Chen, Zhenhua He, Yangliu Cai, Zhenhua Yang, Xianhong Bai
  • Publication number: 20180016353
    Abstract: Provided is a method for obtaining high-yield, stable expression cell clones from myeloma cell lines in a protein-free culture medium. The method is used for industrial production of a recombinant antibody, and includes three stage: (1) adapting to a protein-free culture medium, statically culturing cells at a low density, and gradually reducing a fat-rich supplement to a chemical culture medium; (2) adapting to a protein-free culture medium; culturing cells at a high density, and using a perfusion fermentation system in a laboratory scale; and (3) screening high-yield, stable expression cell clones from the cells after fermentation ends. The cell clone may be used to produce a humanized anti-NeuGcGM3 14F7 recombinant antibody.
    Type: Application
    Filed: March 11, 2016
    Publication date: January 18, 2018
    Inventors: MeyLen CHEA, Julio PALACIOS, Miguel ARIAS, Loany CALVO, Tamara GONZÁLEZ, Rolando PÉREZ, Zhi BAI, Yuemao LIU, Kaiheng XIAO, Xiao CHEN, Zhenhua HE, Yangliu CAI, Zhenhua YANG, Xianhong BAI
  • Patent number: 7920886
    Abstract: Systems and methods for facilitating dispatch communications are provided. Buttons related to dispatch communications can be displayed when dispatch call addresses are received by a mobile station. Additionally, selection menus with options related to dispatch communications can be displayed in a call history display when a dispatch communication is selected. When a contact with a dispatch communication address is selected, a selection menu with options related to dispatch communications can be displayed.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: April 5, 2011
    Assignee: Nextel Communications, Inc.
    Inventors: Duc Dinh Lai, Julio Palacio
  • Patent number: 7899078
    Abstract: Systems and methods for controlling power saving functions of wireless communication stations are provided. A radio interface layer is provided between an operating system and a wireless modem. The radio interface layer controls reinitialization of the operating system and wireless modem when a notification associated with a dispatch communication service is received from a wireless communication network.
    Type: Grant
    Filed: July 14, 2006
    Date of Patent: March 1, 2011
    Assignee: Nextel Communications Inc.
    Inventors: Duc Dinh Lai, Julio Palacio
  • Patent number: 7742780
    Abstract: A method and computer-readable medium for performing predictive name completion, categorizing call lists and accessing dispatch ID numbers in a database for dispatch dialers is provided. The method for performing predictive name completion includes recognizing a portion of a dispatch ID input by a user; determining a name associated with a dispatch ID, based on the portion of the dispatch ID input by the user, and displaying the name. The method for categorizing call lists includes determining a type of each of a plurality of the dispatch calls; and placing each of the plurality of dispatch calls in one of a plurality of categorized lists, based on the type of each of the plurality of dispatch calls. The method for accessing dispatch ID numbers in a database includes establishing a mirror database including the dispatch ID numbers; and searching the mirror database for particular dispatch ID numbers.
    Type: Grant
    Filed: June 21, 2005
    Date of Patent: June 22, 2010
    Assignee: Nextel Communications Inc.
    Inventors: Duc Dinh Lai, Julio Palacio
  • Patent number: 7437163
    Abstract: A method and computer-readable medium for a dual dialer state machine are provided. The state machine allows a Radio Interface Layer (RIL) to make decisions on whether to allow calls to be initiated or terminated depending upon the type of call (interconnect or dispatch). The RIL uses the state machine to coordinate the functions of an interconnect phone application and a dispatch phone application.
    Type: Grant
    Filed: June 21, 2005
    Date of Patent: October 14, 2008
    Assignee: Nextel Communications Inc.
    Inventors: Julio Palacio, Duc Dinh Lai, Denis Londry, Pieter Truter
  • Publication number: 20070010274
    Abstract: A method and computer-readable medium for performing predictive name completion, categorizing call lists and accessing dispatch ID numbers in a database for dispatch dialers is provided. The method for performing predictive name completion includes recognizing a portion of a dispatch ID input by a user; determining a name associated with a dispatch ID, based on the portion of the dispatch ID input by the user, and displaying the name. The method for categorizing call lists includes determining a type of each of a plurality of the dispatch calls; and placing each of the plurality of dispatch calls in one of a plurality of categorized lists, based on the type of each of the plurality of dispatch calls. The method for accessing dispatch ID numbers in a database includes establishing a mirror database including the dispatch ID numbers; and searching the mirror database for particular dispatch ID numbers.
    Type: Application
    Filed: June 21, 2005
    Publication date: January 11, 2007
    Applicant: NEXTEL COMMUNICATIONS, INC.
    Inventors: Duc Lai, Julio Palacio
  • Publication number: 20060286991
    Abstract: A method and computer-readable medium for a dual dialer state machine are provided. The state machine allows a Radio Interface Layer (RIL) to make decisions on whether to allow calls to be initiated or terminated depending upon the type of call (interconnect or dispatch). The RIL uses the state machine to coordinate the functions of an interconnect phone application and a dispatch phone application.
    Type: Application
    Filed: June 21, 2005
    Publication date: December 21, 2006
    Applicant: NEXTEL COMMUNICATIONS, INC.
    Inventors: Julio Palacio, Duc Lai, Denis Londry, Pieter Truter