Patents by Inventor Julius BRUCH

Julius BRUCH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Perk activator for the treatment of neurodegenerative diseases
    Patent number: 10369123
    Abstract: The present invention relates to a novel method for the treatment and/or prophylaxis of a tau-mediated neurodegenerative disease and/or of a tau-mediated neurodegenerative pathological condition, especially of a neurodegenerative disease and/or of a neurodegenerative pathological condition associated with and/or accompanied by tau aggregation, and in particular for the treatment and/or prophylaxis of a tauopathy; compounds and/or agents and compositions for such treatment and/or prophylaxis, and the manufacture of the compounds and/or agents and compositions suitable for the said treatment and/or prophylaxis. In this regard, the present invention relates especially to the use of compounds acting as PERK activator, a prodrug thereof, a derivative thereof and/or a pharmaceutically acceptable salt of any thereof, as a medicament.
    Type: Grant
    Filed: August 14, 2015
    Date of Patent: August 6, 2019
    Assignees: Deutsches Zentrum für Neurodegenerative Erkrankungen E.V. (DZNE), Klinikum Rechts Der Isar Technische Universität München
    Inventors: Günter Höglinger, Julius Bruch, Thomas Rösler
  • PERK ACTIVATOR FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES
    Publication number: 20170304241
    Abstract: The present invention relates to a novel method for the treatment and/or prophylaxis of a tau-mediated neurodegenerative disease and/or of a tau-mediated neurodegenerative pathological condition, especially of a neurodegenerative disease and/or of a neurodegenerative pathological condition associated with and/or accompanied by tau aggregation, and in particular for the treatment and/or prophylaxis of a tauopathy; compounds and/or agents and compositions for such treatment and/or prophylaxis, and the manufacture of the compounds and/or agents and compositions suitable for the said treatment and/or prophylaxis. In this regard, the present invention relates especially to the use of compounds acting as PERK activator, a prodrug thereof, a derivative thereof and/or a pharmaceutically acceptable salt of any thereof, as a medicament.
    Type: Application
    Filed: August 14, 2015
    Publication date: October 26, 2017
    Inventors: Günter HÖGLINGER, Julius BRUCH, Thomas RÖSLER