Abstract: The present disclosure relates to compositions and related methods to reduce body weight, body fat, waist and hip size, plasma total cholesterol, LDL, triglycerides, blood glucose, leptin and C-reactive protein levels and increase in HDL and serotonin levels in an mammal. The LeptiCore® formulation disclosed, at both the low and high dosages, is helpful in the management of fat gain and its related complications. The higher dosage resulted in significantly greater reductions in body weight and triglyceride, blood glucose, and C-reactive protein levels, as well as increased serotonin levels.

Abstract: Methods of improving a variety of health related factors including, but not limited to weight, cholesterol levels, triglyceride levels and HDL levels, is provided. In one embodiment, a method of reducing body weight in a mammal is provided; the method comprises administering a composition containing an effective amount of Dichrostachys glomerata, to the mammal, whereby the administering of the composition to the mammal is effective in reducing bodyweight in the mammal.

Abstract: Methods of improving a variety of health related factors including, but not limited to weight, cholesterol levels, triglyceride levels and HDL levels, is provided. In one embodiment, a method of reducing body weight in an overweight subject is provided; the method comprises administering a composition containing an effective amount of Hypodaphnis zenkeri, to an overweight subject, whereby the administering of the composition to the overweight subject is effective in reducing bodyweight in the overweight subject.

Abstract: Methods of improving a variety of health related factors including, but not limited to weight, cholesterol levels, triglyceride levels and HDL levels, is provided. In one embodiment, a method of reducing body weight in a mammal is provided; the method comprises administering a composition containing an effective amount of Xylopia aethiopica, to the mammal, whereby the administering of the composition to the mammal is effective in reducing bodyweight in the mammal.

Abstract: Methods of improving a variety of health related factors including, but not limited to weight, cholesterol levels, triglyceride levels and HDL levels, is provided. In one embodiment, a method of reducing LDL cholesterol levels of a mammal in need thereof is provided, the method comprises administering a composition containing an effective amount of Dichrostachys glomerata, to a mammal, whereby the administering of the composition to the mammal is effective in reducing LDL cholesterol levels in the mammal.

Abstract: The present disclosure relates to compositions and related methods to reduce body weight, body fat, waist and hip size, plasma total cholesterol, LDL, triglycerides, blood glucose, leptin and C-reactive protein levels and increase in HDL and serotonin levels in an mammal. The LeptiCore® formulation disclosed, at both the low and high dosages, is helpful in the management of fat gain and its related complications. The higher dosage resulted in significantly greater reductions in body weight and triglyceride, blood glucose, and C-reactive protein levels, as well as increased serotonin levels.

Abstract: Methods of improving a variety of health related factors including, but not limited to weight, cholesterol levels, triglyceride levels and HDL levels, is provided. In one embodiment, a method of reducing LDL cholesterol levels of a mammal in need thereof is provided, the method comprises administering a composition containing an effective amount of dichrostachys glomerata, to a mammal, whereby the administering of the composition to the mammal is effective in reducing LDL cholesterol levels in the mammal.

Abstract: In one embodiment, a method is provided for lowering PPAR-Gamma in a mammal. The method comprises administering a composition containing an effective amount of Irvingia gabonensis seed to a mammal to reduce PPAR-Gamma levels in the mammal. In other embodiments, among other things, methods are provided for reducing triglyceride levels, inhibiting or reducing G3PDH activity, reducing body weight and increasing adiponectin levels in a mammal by administering Irvingia gabonensis.

Abstract: In one embodiment, a method is provided for lowering C-reactive protein levels in a mammal. The method comprises administering a composition containing an effective amount of Irvingia gabonensis seed to a mammal to reduce C-reactive protein levels in the mammal. Other embodiments include, among other things, lowering leptin levels, increasing adiponectin levels, reducing body weight, decreasing LDL and total cholesterol levels, increasing fat loss, and reducing waist size in a mammal using administering a composition containing an effective amount of Irvingia gabonensis.