Patents by Inventor Julius Matasi

Julius Matasi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DERIVATIVES OF 7,8-DIHYDRO-1H-IMIDAZO[2,1-b] PURIN-4(5H)-ONE and METHODS OF USE THEREOF
    Publication number: 20120316176
    Abstract: The present invention relates to derivatives of 7,8-dihydro-1H-imidazo[2,1-b]purin-4(5H)-one, compositions thereof and methods of use thereof for treating or preventing pain or an inflammatory disease.
    Type: Application
    Filed: December 16, 2010
    Publication date: December 13, 2012
    Inventors: Deen Tulshian, Michael F. Czarniecki, Julius Matasi, Stephanie N. Brumfield
  • mGluR1 Antagonists as therapeutic agents
    Publication number: 20060167029
    Abstract: In its many embodiments, the present invention provides tricyclic compounds of formula I (wherein J1-J4, X, and R1-R5 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, particularly as selective metabotropic glutamate receptor 1 antagonists, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds and compositions to treat diseases associated with metabotropic glutamate receptor (e.g., mGluR1) such as, for example, pain, migraine, anxiety, urinary incontinence and neurodegenerative diseases such Alzheimer's disease.
    Type: Application
    Filed: December 13, 2005
    Publication date: July 27, 2006
    Inventors: Julius Matasi, Deen Tulshian, Duane Burnett, Wen-Lian Wu, Peter Korakas, Lisa Silverman, Thavalakulamgara Sasikumar, Li Qiang, Martin Domalski
  • mGluR1 antagonists as therapeutic agents
    Publication number: 20060009477
    Abstract: In its many embodiments, the present invention provides tricyclic compounds of formula I (wherein J1-J4, X, and R1—R5 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, particularly as selective metabotropic glutamate receptor 1 antagonists, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds and compositions to treat diseases associated with metabotropic glutamate receptor (e.g., mGluR1) such as, for example, pain, migraine, anxiety, urinary incontinence and neurodegenerative diseases such Alzheimer's disease.
    Type: Application
    Filed: June 14, 2005
    Publication date: January 12, 2006
    Inventors: Julius Matasi, Deen Tulshian, Duane Burnett, Wen-Lian Wu, Peter Korakas, Lisa Silverman, Thavalakulamgara Sasikumar, Li Qiang, Martin Domalski