Abstract: Embodiments of the present disclosure include compositions and methods for treating type 2 diabetes using anti-diabetic steroidal lactones of Withania Coagulans, such as Coagulansin A and derivatives and analogues thereof are described. For example, a method of treating type 2 diabetes in a subject in need thereof, the method comprising administering a therapeutically effective amount of Coagulansin A or a derivative or analogue thereof to the subject is provided. Further described embodiments include compositions and methods of treating muscle atrophy in a subject with type 2 diabetes by initiating regeneration of diseased skeletal muscle myoblasts using anti-diabetic steroidal lactones of Withania Coagulans.

Abstract: A media creation system is provided for creating photographs and videos that include assets sourced from different geographic locations. The media creation system may perform parsing media, transposition the media, and/or perform additional modifications to the media. A method for creating photographs, videos, and live streams of one or more assets sourced from different geographic locations using the audiovisual media composition system is also provided. Communication, chat, and rating features are also provided.

Abstract: Roof airbags and methods for installation of the roof airbags in vehicles are provided. The roof airbags include a deployable airbag configured to automatically inflate in response to detection of a sensed event and to cover portions of an interior side of a vehicle upon being inflated, a continuous mounting tab extending from and along the deployable airbag that includes first and second mounting holes configured to receive first and second fasteners for securing the continuous mounting tab to a frame of the vehicle at first and second positions, respectively, and a reinforcement member disposed on the continuous mounting tab that is configured to prevent alignment of the first mounting hole and/or the second mounting hole with the first position and/or the second position, respectively, on the frame in response to the deployable airbag being twisted.

Abstract: Certain examples relate to a method for manufacturing a ceramic object derived from a 3D printed ceramic structure. The method includes carbonizing the 3D printed ceramic structure. Such carbonizing of the 3D printed ceramic structure may include introducing a network of carbon bonding into the 3D printed ceramic structure via: impregnating and/or coating the 3D printed ceramic structure with a carbon precursor, or printing the 3D printed ceramic structure using a ceramic printing medium including a carbon precursor. The resultant 3D printed ceramic structure which includes a carbon precursor is pyrolyzed so as to form a network of carbon bonding within/surrounding the 3D printed ceramic structure.

Abstract: An unmanned aerial vehicle (UAV) includes a fuselage, electronics disposed with the fuselage, a heat sink, and a solar shield. The heat sink is thermally connected to the electronics and includes a cooling plate disposed on or extends through an exterior surface of the fuselage. The cooling plate is exposed to an external environment of the UAV to conduct heat from the electronics to the external environment via convection. The solar shield extends over the cooling plate and defines an air scoop within which the cooling plate is disposed. The air scoop directs airflow from the external environment across the cooling plate. The solar shield shades the cooling plate from solar radiation to prevent or reduce solar heating of the cooling plate.

Abstract: Certain examples of the present invention relate to a method for manufacturing a ceramic object derived from a 3D printed ceramic structure. The method comprises: carbonising the 3D printed ceramic structure. Such carbonising of the 3D printed ceramic structure may comprise introducing a network of carbon bonding into the 3D printed ceramic structure via: impregnating and/or coating the 3D printed ceramic structure with a carbon precursor, or printing the 3D printed ceramic structure using a ceramic printing medium comprising a carbon precursor. The resultant 3D printed ceramic structure which comprises a carbon precursor is pyrolysed so as to form a network of carbon bonding within/surrounding the 3D printed ceramic structure.

Abstract: The invention features compact systems and methods for vacuum liquid purification and extraction of a liquid sample.

Abstract: In an example, a vehicle seat sensor system includes a vehicle seat, a flexible seat sensor, and an electronics unit. The vehicle seat includes a seat surface. The flexible seat sensor is disposed within a deformable distance from the seat surface and includes one or more signal electrodes, one or more ground electrodes, one or more dielectric layers, and one or more capacitors. Each capacitor is formed by a combination of a corresponding signal electrode and a corresponding ground electrode with a corresponding dielectric layer positioned between the corresponding signal electrode and the corresponding ground electrode. The electronics unit is connected to the flexible seat sensor and is configured to electrically communicate with the flexible seat sensor. The flexible seat sensor is configured to provide a capacitive output proportional to an amount of pressure applied to the flexible seat sensor.

Abstract: A method and device for monitoring combustible matter in a hot gaseous stream and generating a control signal, a controlled jet of an oxidant is injected into the gaseous stream with a lance extending between a window of a monitoring device and the flow path of the gaseous stream, the lance defining a line of sight between the window and the gaseous stream in the flow path, the combustible matter burns with the oxidant in a flame in the gaseous stream in front of the lance, one or more properties of the flame which are correlated with the concentration of combustible matter in the gaseous stream are detected by the monitoring device through the line of sight and the window and the monitoring device processes the one or more detected flame properties and generates a control signal on the basis of the one or more detected flame properties.

Abstract: The present invention provides improved methods for formulating therapeutic compositions comprising an antibody drug conjugate (“ADC”) that reduce potency variability between batches of ADC and provide for administration of such therapeutic compositions within a narrow intended range.

Abstract: Embodiments of the present disclosure include compositions and methods for treating type 2 diabetes using anti-diabetic steroidal lactones of Withania Coagulans, such as Coagulansin A and derivatives and analogues thereof are described. For example, a method of treating type 2 diabetes in a subject in need thereof, the method comprising administering a therapeutically effective amount of Coagulansin A or a derivative or analogue thereof to the subject is provided. Further described embodiments include compositions and methods of treating muscle atrophy in a subject with type 2 diabetes by initiating regeneration of diseased skeletal muscle myoblasts using anti-diabetic steroidal lactones of Withania Coagulans.

Abstract: Certain examples of the present disclosure relate to a method for manufacturing a ceramic object, the method comprising: forming a ceramic structure by 3D printing the ceramic structure with a binder jetting 3D ceramic printer using a ceramic powder and an inorganic binder, wherein the ceramic powder comprises sintered ceramic material; and firing the ceramic structure to form the ceramic object.

Abstract: A media creation system is provided for creating photographs and videos that include assets sourced from different geographic locations. The media creation system may perform parsing media, transposition the media, and/or perform additional modifications to the media. A method for creating photographs, videos, and live streams of one or more assets sourced from different geographic locations using the audiovisual media composition system is also provided. Communication, chat, and rating features are also provided.

Abstract: Signed digital certificates can be automatically obtained from a trusted certificate authority. For example, a computing device can receive a request associated with a handshake procedure for establishing a secure session between a client device and a server. The request can indicate a trusted certificate authority that issues signed digital certificates. The computing device can determine that a local key store that is local to the server does not have a signed digital certificate issued by the trusted certificate authority and responsively obtain the signed digital certificate from the trusted certificate authority. The computing device can return the signed digital certificate back to the client device as part of the handshake procedure to establish the secure session.

Abstract: An unmanned aerial vehicle (UAV) includes a fuselage, electronics disposed with the fuselage, a heat sink, and a solar shield. The heat sink is thermally connected to the electronics and includes a cooling plate disposed on or extends through an exterior surface of the fuselage. The cooling plate is exposed to an external environment of the UAV to conduct heat from the electronics to the external environment via convection. The solar shield extends over the cooling plate and defines an air scoop within which the cooling plate is disposed. The air scoop directs airflow from the external environment across the cooling plate. The solar shield shades the cooling plate from solar radiation to prevent or reduce solar heating of the cooling plate.

Abstract: A media creation system is provided for creating photographs and videos that include assets sourced from different geographic locations. The media creation system may parsing media, transposition the media, and/or perform additional modifications to the media. A method for creating photographs, videos, and live streams of one or more assets sourced from different geographic locations using the audiovisual media composition system is also provided.

Abstract: Process for combusting a fuel with an oxidant and burner for the implementation thereof, process wherein at least one stream of the fuel is injected through at least one first perforation, a main flow of oxidant is injected below or above the one or more streams of the fuel through at least one second perforation, an auxiliary flow of the oxidant is introduced into contact with the at least one fuel stream so as to generate an initial flame by an initial partial combustion of the fuel with the auxiliary flow of the oxidant, this initial partial combustion being completed downstream of the initial flame by means of the at least one main stream of the oxidant, the flow rate of the main flow of the oxidant or the ratio between the flow rate of the main flow of the oxidant and the flow rate of the auxiliary flow of the oxidant being adjusted depending on the emission intensity of the initial flame.

Abstract: A method includes with a computing system, receiving an attribute within a managed configuration model, the attribute referencing a credential store and associated with a resource, with the computing system, in response to determining that the attribute includes both an alias and a clear-text password, determining whether there is a matching entry within the credential store, and in response to determining that the credential store does not contain a matching entry: creating a new entry for the credential store, wherein the new entry includes the clear-text password and is uniquely identifiable using the alias, and removing the clear-text password from the managed configuration model.

Abstract: Certain aspects and features provide an automated process for a server switching from a self-signed digital certificate to a digital certificate signed by a trusted certificate authority (CA). During initiation of an encrypted communication session, for example, during a transport layer security (TLS) handshake, upon receiving a client hello message, the server determines if it is using a self-signed digital certificate. If so, the server automatically creates and sends a certificate signing request, receives a CA-signed digital certificate, and replaces the self-signed digital certificate in its key store with the CA-signed digital certificate. The server then includes the new, CA-signed digital certificate in the server hello message sent back to the client to establish the encrypted communication session.

Abstract: Certain aspects and features provide an automated process for a server switching from existing digital certificate that is expired or about to expire to a new digital certificate signed by a trusted certificate authority (CA). During initiation of an encrypted communication session, for example, during a transport layer security (TLS) handshake, upon receiving a client hello message, the server determines whether it is using a renewable digital certificate. If so, the server automatically creates and sends a certificate signing request; receives a new, CA-signed digital certificate; and replaces the existing digital certificate in its key store with the new digital certificate. The server then includes the new digital certificate in the server hello message sent back to the client to establish the encrypted communication session.