Abstract: This application discloses 5-phenyl-1H-pyridin-2-one, 6-phenyl-2H-pyridazin-3-one, and 5-Phenyl-1H-pyrazin-2-one derivatives according to generic Formulae I-III: wherein, variables Q, R, X, X?, Y1, Y2, Y2?, Y3, Y4, Y5, m, and n are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are further useful to treat inflammatory and auto immune diseases associated with aberrant B-cell proliferation such as rheumatoid arthritis. Also disclosed are compositions containing compounds of Formulae I-III and at least one carrier, diluent or excipient.

Abstract: Provided is an organic metal complex having a structure represented by the following general formula (1): MLmL?n??(1) where: M represents a metal atom selected from Ir, Pt, Rh, Os, and Zn; L and L?, which are different from each other, each represent a bidentate ligand; m represents an integer of 1 to 3 and n represents an integer of 0 to 2, provided that m+n is 3; a partial structure MLm represents a structure represented by the following general formula (2): and a partial structure ML?n represents a structure including a monovalent bidentate ligand.

Abstract: This invention mainly involves in the consumer electronic product fields, especially in the protective devices against abnormality for positive and negative power circuits of TV and audio technology field. In one embodiment, in the last stage output port load (RL) circuit of the dual power supply, a series current negative feedback resistor R371 is added or used as the detection source, by the integration of Resistor R46V and Capacitor C46V, and then through the pressure-sensitive switching unit VD46 or Diode D46 branch circuit, is connected with normally closed and overload conducting overload shutdown devices so as to perform timely and effective protection against OCL circuit over current or other abnormalities in the positive and negative power supply.

Abstract: A parking assist apparatus includes a guidance mode setting portion specifying a forward turning guidance controlling portion to perform a control when determining that a direct guidance control for driving a vehicle rearward to a target parking position without once driving the vehicle forward is unachievable. The forward turning guidance controlling portion includes an auxiliary guidance controlling device generating an auxiliary guidance path and driving the vehicle rearward by an automatic steering along the auxiliary guidance path and a guidance possibility determining device determining whether or not the vehicle is directly guided rearward to the target parking position based on a position and a steering angle of the vehicle while the vehicle is moving forward by a manual steering. The forward turning guidance controlling portion includes a final guidance controlling device guiding the vehicle to the target parking position.

Abstract: Disclosed are a bitstream decoding apparatus and a method thereof. The decoding apparatus can include: a decoder forming unit, configured to generate and output CSCI control information and connection control information by using partial decoder descriptions stored in a description storing unit; and a decoding solution, which selectively loads a plurality of functional units included in a toolbox by using the CSCI control information and the connection control information to decode a bitstream to video data. With the present invention, it is possible to decode various types of bitstreams according to each of various standards by using an identical information recognizing method.

Abstract: A method for controlling a rate of a voice service in a mobile communication system supporting the voice service via a packet network. The method includes the steps of receiving a control message at a terminal from a radio network controller (RNC); if the control message indicates control of a downlink rate, determining a downlink rate according to the control message; setting a Change Mode Request (CMR) field of an uplink Voice over Internet Protocol (VoIP) packet according to the downlink rate, and transmitting the uplink VoIP packet from the terminal to the RNC; if the received control message indicates control of an uplink rate, determining an uplink rate according to the control message; and generating an uplink VoIP packet including uplink voice data generated according to the determined uplink rate and frame type (FT) information indicating the determined uplink rate, and transmitting the uplink VoIP packet from the terminal to the RNC.

Abstract: An image forming apparatus includes a first read device configured to read a first surface of an original document in a main scanning direction and to produce a first band data. The image forming apparatus further includes a second read device configured to read a second surface of the original document in the main scanning direction and to produce a second band data during the reading of the first surface by the first read device. The image forming apparatus still further includes an image data processor configured to produce printing band data by combining the first band data with the second band data, during the reading of at least one of the first surface and the second surface. Moreover, the image forming apparatus includes a printing device configured to start printing an image of the printing band data produced by the image data processor on a printing sheet, during the reading of at least one of the first surface and the second surface.

Abstract: A nonvolatile memory device stores program data in a first address area, determines whether the first address area is a most significant address area and whether the program data is reliable data, and upon determining that the first address area is not a most significant address area and that the program data is reliable data, additionally stores the program data in a second address area.

Abstract: A lubrication structure for a multi-speed transmission has a lubrication structure in which a gear shaft is provided with cam guide grooves in an inner cavity thereof. A lubricating oil is introduced into the inner cavity by way of oil feed introducing holes which are bored in one end portion of the gear shaft so as to provide communication between the inside and the outside of the gear shaft. The lubricating oil is led in the axial direction along the inner peripheral surface of the inner cavity by axial oil feed grooves formed by cutting along the inner peripheral surface of the inner cavity in parallel to the cam guide grooves. The lubricating oil is led out to the engagement switch-over mechanism by radial oil feed holes bored in radial directions so as to communicate with the axial oil feed grooves at axial-direction positions where pin members are located.

Abstract: A method for operating an internal combustion engine including extended operation in a homogeneous charge compression ignition mode at high loads includes operating the engine in the homogeneous charge compression ignition mode including spark-assisted ignition, monitoring an engine load, monitoring an engine speed, determining the engine to be in a high ringing range based upon the engine load and the engine speed, and when the engine load is in the high ringing range, operating the engine in a reduced ringing mode. The reduced ringing mode includes modulating a fuel injection timing according to a calibrated maximum combustion chamber cooling fuel injection timing, determining a preferred combustion phasing value, and modulating a spark timing based upon the modulated fuel injection timing and the preferred combustion phasing value.

Abstract: The present invention provide a preparation method of composite blue luminescent thin film of sulfonated poly(p-phenylene) (i.e. poly[2,5-bis(3-sulfonatopropoxy)-1,4-phenylene-alt-1,4-phenylene]) and LDHs (Layered Double Hydroxides). The preparation method comprises following steps: preparing delaminated LDHs colloidal solution using formamide solvent, preparing sulfonated poly(p-phenylene) aqueous solution, performing alternate assembling on hydrophilically treated substrate in the two solutions to give the composite thin film of sulfonated poly(p-phenylene)/LDHs multilayer. The present invention has the advantages of simple preparation process, and film thickness controllable at nanoscale precision; the invention also achieves the immobilization of luminescent polymer via restricted space among LDHs layers and host-guest interaction, effectively improves thermal stability, and reduces fluorescence quenching caused by aggregation.

Abstract: A hollow-cathode discharge apparatus is disclosed for plasma-based processing. The hollow-cathode discharge apparatus includes a vacuum chamber, a hollow cathode disposed in the center of the vacuum chamber, a carrier for synchronously carrying a plurality of work-pieces in the vacuum chamber and a driving element for driving the carrier.

Abstract: Work is performed in cooperation in a common region by a plurality of apparatuses and a human being, and at this time, human resources are used effectively, and the work is performed efficiently. When components A, B and C are processed by three apparatuses a, b and c and one person in, in the first process, the component A is processed by the person m, and the components B and C are processed by the two apparatuses b and c. In the second process, the component B is processed by the person in, and the components A and C are processed by the two apparatuses a and c. In the third process, the component C is processed by the person m, and the components A and B are processed by the two apparatuses a and b. The timings at which the person m intervenes in the respective apparatuses are prevented from overlapping in this manner, by which the work is performed efficiently.

Abstract: Vertical power devices which include an insulated trench containing insulating material and a gate electrode, and related methods. A body region is positioned so that a voltage bias on the gate electrode will cause an inversion layer in the body region. A layer of permanent charge, at or near the sidewall of the trench, provides charge balancing for the space charge in the depleted semiconductor material during the OFF state. A conductive shield layer is positioned below the gate electrode in the insulating material, and reduces capacitive coupling between the gate and the lower part of the trench. This reduces switching losses. In other embodiments, a planar gate electrode controls horizontal carrier injection into the vertical conduction pathway along the trench, while a shield plate lies over the trench itself to reduce capacitive coupling.

Abstract: Methylotrophic or methanotrophic bacteria such as Methylobacterium are transformed with a gene of interest, and expression of the gene is regulated by means of a cumate repressor protein and an operator sequence which is operatively linked to the gene of interest, and the addition of an external agent. Specifically, the cymR repressor and cmt operator from Pseudomonas putida may serve to regulate gene expression in methylotrophic or methanotrophic bacteria with the addition of cumate.

Abstract: An arrangement structure of a shifting actuator of an internal combustion engine mounted on a motorcycle is provided in which while the shifting actuator is provided externally of an engine case of the engine so as not to interfere with auxiliaries, it is protected without external protrusion and external appearance is kept satisfactory. An external wall of an engine case is partially inwardly recessed to form a recessed portion capable of accommodating a shifting actuator. An actuator body of the shifting actuator is disposed in the recessed portion. An attachment bracket attached to an end portion of the actuator body is fitted to a first fitting hole of an engine case outer lateral wall on the side of the recessed portion and is secured to the engine case outer wall. The motorcycle has a multistage transmission that can reduce its axial width to achieve compactness.

Abstract: A sheet size detecting apparatus having a first arm moved by a moving sheet contacting therewith, a second arm moved by the moving sheet contacting therewith, the second arm being disposed at a location differing from that of the first arm in a direction orthogonal to the movement direction of the sheet, and a sensor, wherein the output level of the sensor when only one of the first arm and the second arm has been moved is the same as the output level thereof when neither of the first arm and the second arm is moved, and the output level of the sensor when both of the first arm and the second arm have been moved differs from the output level thereof when neither of the first arm and the second arm is not moved. Thereby, the cost can be suppressed and yet, the wrong detection of the sheet size can be prevented.

Abstract: Novel devices and methods are provided, which include electroporative flow cytometry, where electroporation is combined with flow cytometry. The devices and methods can be used for the detection a variety of cellular features, including protein translocation, and for monitoring biomechanics at single cell level. Using the novel devices methods it is possible to observe the release of proteins such as intracellular kinases out of the cells during electroporation. Using the novel devices methods it is possible to study cytoskeleton dynamics and deformability at a single cell level, and to correlate these to diseases such as cancers.

Abstract: Methods of preparing single walled carbon nanotubes are provided. An arrangement comprising one or more layers of fullerene in contact with one side of a metal layer and a solid carbon source in contact with the other side of metal layer is prepared. The fullerene/metal layer/solid carbon source arrangement is then heated to a temperature below where the fullerenes sublime. Single walled carbon nanotubes are grown on the fullerene side of the metal layer.

Abstract: There are provided a light emitting device package and a method for manufacturing the same. The light emitting device includes: a plurality of barriers provided above a metal circuit board; a plurality of light emitting devices placed in a space between the barriers; and a lens unit provided at an upper side of the barrier. Accordingly, the plurality of light emitting devices can be conveniently seated as a module format, and a luminance can be increased. Also, an efficiency of heat sink can be increase.