Abstract: A time-of-flight mass spectrometer includes a beam irradiation unit that generates an ionized particle by emitting an ion beam in a pulse form to a sample, a mass spectrometry unit that causes the ionized particle to fly, an MCP disposed in the mass spectrometry unit to measure a mass by amplifying the ionized particle, an MCP power source that applies a voltage to the MCP, and an MCP gain adjustment unit that adjusts a gain of the voltage. The MCP gain adjustment unit adjusts the gain of the voltage until a subsequent pulse is emitted after the beam irradiation unit emits a first pulse of the ion beam.

Abstract: A time-of-flight mass spectrometer includes a beam irradiation unit that generates an ionized particle by emitting an ion beam in a pulse form to a sample, a mass spectrometry unit that causes the ionized particle to fly, an MCP disposed in the mass spectrometry unit to measure a mass by amplifying the ionized particle, an MCP power source that applies a voltage to the MCP, and an MCP gain adjustment unit that adjusts a gain of the voltage. The MCP gain adjustment unit adjusts the gain of the voltage until a subsequent pulse is emitted after the beam irradiation unit emits a first pulse of the ion beam.

Abstract: According to an embodiment, a mass spectrometry apparatus includes a beam irradiator, a laser irradiator, a mass spectrometer and a controller. The beam irradiator irradiates a sample with an ion beam. The laser irradiator irradiates a space above the sample with laser light. The mass spectrometer performs mass spectrometry of an ionized particle. The controller controls at least one of the laser irradiator and the mass spectrometer on the basis of an analysis result of the mass spectrometer.

Abstract: According to an embodiment, a mass spectrometry apparatus includes a beam irradiator, a laser irradiator, a mass spectrometer and a controller. The beam irradiator irradiates a sample with an ion beam. The laser irradiator irradiates a space above the sample with laser light. The mass spectrometer performs mass spectrometry of an ionized particle. The controller controls at least one of the laser irradiator and the mass spectrometer on the basis of an analysis result of the mass spectrometer.

Abstract: An object to be solved by the present invention is to provide, for example, a method for producing a Kluyveromyces marxianus transformant by a method for conveniently and efficiently connecting the ends of DNA fragments without using specific restriction enzymes or their recognition sequences, and a method for producing a useful substance using the transformant.

Abstract: An object to be solved by the present invention is to provide, for example, a method for producing a Kluyveromyces marxianus transformant by a method for conveniently and efficiently connecting the ends of DNA fragments without using specific restriction enzymes or their recognition sequences, and a method for producing a useful substance using the transformant.

Abstract: A forging die production method comprising a cutting step which employs, as a cutting tool, a ball end mill having a surface which has undergone a hardening treatment and in which a forging die material is cut under conditions where a length of tool extension L (mm), radius R (mm) of a cutting edge of the ball end mill, spindle speed A (rpm) and feed rate B (mm/min) satisfy (B/A)2×(L/(2×R))=0.01 to 0.05. A forging die is produced through the forging die production method. A forged article is produced through forging by use of the produced forging die.

Abstract: A forging die production method comprising a cutting step which employs, as a cutting tool, a ball end mill having a surface which has undergone a hardening treatment and in which a forging die material is cut under conditions where a length of tool extension L (mm), radius R (mm) of a cutting edge of the ball end mill, spindle speed A (rpm) and feed rate B (mm/min) satisfy (B/A)2×(L/(2×R))=0.01 to 0.05. A forging die is produced through the forging die production method. A forged article is produced through forging by use of the produced forging die.