Abstract: A cell inspection method includes a concentrate production step, a staining step, a cell precipitation step, and an observation step. In the concentrate production step, the cell concentrate is produced by causing an inner cylinder which has a filter provided on a bottom surface to enter from the bottom surface side into the through hole of the outer cylinder and bringing the inner cylinder closer to the slide, the inner cylinder having an internal space, and in the observation step, observation is performed in a state where the inner cylinder is entered into the outer cylinder.

Abstract: A cell inspection method includes a concentrate production step, a staining step, a cell precipitation step, and an observation step. In the concentrate production step, the cell concentrate is produced by causing an inner cylinder which has a filter provided on a bottom surface to enter from the bottom surface side into the through hole of the outer cylinder and bringing the inner cylinder closer to the slide, the inner cylinder having an internal space, and in the observation step, observation is performed in a state where the inner cylinder is entered into the outer cylinder.

Abstract: Provided is an image-processing method including: an image-acquiring step of acquiring a divided-section image that includes the entire divided section by capturing an image of a chip array obtained by dividing a substrate into numerous chips together with a section of biological tissue on the substrate; a chip-recognizing step of recognizing chip images in the divided-section image; an attribute-information assigning step of assigning, to each of pixels that constitute the images of the recognized chips, positional information of the chip images to which those pixels belong in the image of the chip array; and a restoring step of generating a restored section image in which images of the divided section are joined into a single image by joining the chip images constituted of the pixels to which the positional information has been assigned.

Abstract: Provided is a cell collection apparatus includes: a supporter that supports a sheet to which a back surface of a substrate is pasted, the substrate being divided in to plural small pieces with a section of a tissue pasted on a front surface thereof; a needle including needle tips; and a holder that is configured to hold the needle with the needle tips facing the sheet on an opposite side to a substrate side of the sheet, and to move the needle in the forward direction of the needle tips, wherein at least two needle tips are arranged within a region narrower than the back surface of the small piece substantially on the identical plane intersecting with the longitudinal direction of the needle.

Abstract: A group of small pieces of divided base substrate is arrayed on a sheet without gaps therebetween by means of a simple method. Provided is a substrate-sheet fabricating method including cutting into a group of small pieces a base substrate whose first-side surface is attached to a first sheet member; transferring the group of small pieces to a second sheet member by attaching the second sheet member, which can be contracted in the direction along a surface thereof, to second-side surfaces of the group of small pieces and by peeling off the first sheet member from the first-side surfaces of the group of small pieces; and making the second sheet member contract in the direction along the surface thereof.

Abstract: Provided is a cell collection apparatus includes: a supporter that supports a sheet to which a back surface of a substrate is pasted, the substrate being divided in to plural small pieces with a section of a tissue pasted on a front surface thereof; a needle including needle tips; and a holder that is configured to hold the needle with the needle tips facing the sheet on an opposite side to a substrate side of the sheet, and to move the needle in the forward direction of the needle tips, wherein at least two needle tips are arranged within a region narrower than the back surface of the small piece substantially on the identical plane intersecting with the longitudinal direction of the needle.

Abstract: A group of small pieces of divided base substrate is arrayed on a sheet without gaps therebetween by means of a simple method. Provided is a substrate-sheet fabricating method including cutting into a group of small pieces a base substrate whose first-side surface is attached to a first sheet member; transferring the group of small pieces to a second sheet member by attaching the second sheet member, which can be contracted in the direction along a surface thereof, to second-side surfaces of the group of small pieces and by peeling off the first sheet member from the first-side surfaces of the group of small pieces; and making the second sheet member contract in the direction along the surface thereof.

Abstract: A substrate and an elastomer are bonded each other, and then, a ditch is formed at the bonded surface of the substrate or the elastomer to constitute a flow channel and thus, to constitute a minute flow channel device with the flow channel. Then, a through-hole functioning an inlet and/or outlet is formed at the elastomer so as to be communicated with the flow channel. Then, a convex or concave joint is formed at the elastomer with integration so as to be opened outward from the through-hole so that the inclination angle of said joint is set to not less than 45 degrees and less than 90 degrees. Then, a joining device is pressed and joined with the minute flow channel device via the joint. Therefore, the connection for injecting and discharging a substance such as fluid or gas can be easily realized and automatized, and the device exchange can be performed easily.

Abstract: An electric charge generator for use in an apparatus for producing an electrostatic latent image includes a plurality of charge generation controlling devices, each charge generation controlling device including: an insulating substrate; a line electrode formed on the insulating substrate; a solid dielectric film formed on the surface of the line electrode; a finger electrode having a hole for generating an electric charge, the hole being formed in the central part of the finger electrode, the finger electrode being formed on the solid dielectric film; a solid insulating film having a hole for passing the electric charge, the hole being formed in the central part of the solid insulating film, the solid insulating film being formed on the finger electrode; and a screen electrode having a hole for ejecting the electric charge, the hole being formed in the central part of the screen electrode, the screen electrode being formed on the surface of the finger electrode via the solid insulating film; wherein the plur

Abstract: A scanning probe microscope according to the present invention comprises a cantilever having a free end portion and a fixed end portion, the free end portion bearing a probe thereon, a semiconductor laser attached to the fixed end portion of the cantilever, an optical waveguide for guiding a laser beam, emitted from the semiconductor laser, to the free end portion, an optical element for dividing part of a center beam of the laser beam, guided through the optical waveguide, into laser beams in at least two perpendicular directions, a photoelectric transducer for receiving the divided laser beams and converting the laser beams into electrical output signals corresponding thereto, and a differential circuit for receiving the electrical signals and subjecting the signals to predetermined arithmetic processing, thereby detecting a three-dimensional displacement of the free end portion of the cantilever.

Abstract: A scanning probe microscope according to the present invention comprises a cantilever having a free end portion and a fixed end portion, the free end portion bearing a probe thereon, a semiconductor laser attached to the fixed end portion of the cantilever, an optical waveguide for guiding a laser beam, emitted from the semiconductor laser, to the free end portion, an optical element for dividing part of a center beam of the laser beam, guided through the optical waveguide, into laser beams in at least two perpendicular directions, a photoelectric transducer for receiving the divided laser beams and converting the laser beams into electrical output signals corresponding thereto, and a differential circuit for receiving the electrical signals and subjecting the signals to predetermined arithmetic processing, thereby detecting a three-dimensional displacement of the free end portion of the cantilever.

Abstract: An optical waveguide apparatus comprising a substrate made of material the refractive index of which is changed by an electric effect, and an optical waveguide which is formed on a portion of the substrate and allows passage of guided light. In the apparatus, the optical waveguide includes an optical path changing section for periodically producing an electromotive force under the control of one of control light and guided light.