Abstract: Generating transportation network solutions using graph neural networks, includes: generating, based on input data describing a product transportation network, a graph neural network representing the product transportation network, wherein the graph neural network comprises multiple edges, multiple source nodes, multiple destination nodes, and multiple intermediary nodes; performing a graph neural network prediction based on the graph neural network, wherein performing the graph neural network prediction comprises predicting inclusion in the transportation network solution for each edge and intermediary node; and generating a transportation network solution by performing a model optimization using an initial state based on the graph neural network prediction.

Abstract: The present invention provides an interfering RNA targeting TOP1 gene. The interfering RNA can reduce the expression of TOP1, thereby treating a disease related to TOP1 expression. The present invention further provides a lipid nanoparticle drug comprising the interfering RNA for treating a disease related to TOP1 expression. The present invention further provides an antibody-nucleic acid conjugate drug comprising the interfering RNA for treating a disease related to TOP1 expression.

Abstract: A Monte Carlo tree structure of related software packages for a software project is constructed, wherein one or more vulnerable nodes of the Monte Carlo tree structure indicate a software vulnerability. A Monte Carlo tree search algorithm is applied on the Monte Carlo tree structure, the applying comprising expanding the Monte Carlo tree structure with multiple respective candidate nodes corresponding to alternative software packages for replacement of the one or more vulnerable nodes and performing iterative simulation and backpropagation through different tree updates using the multiple respective candidate nodes to identify at least one best replacement node from the multiple candidate nodes. A repaired software set for the software project is exported, the repaired software set including additional software corresponding to the at least one identified best replacement node, the additional software replacing one or more software packages that are related to the one or more vulnerable nodes.

Abstract: A method for improving wheat resistance to Fusarium head blight (FHB) by genome editing is provided, and further provided is use of TaCIPK14 protein or related biomaterial thereto in the regulation of plant resistance to FHB; the TaCIPK14 protein is TaCIPK14-4A protein (SEQ ID NO: 4), TaCIPK14-4B protein (SEQ ID NO: 5), and/or TaCIPK14-4D protein (SEQ ID NO: 6). TaCIPK14 knockout mutant plants are successfully obtained by simultaneously editing three alleles of TaCIPK14 in wheat using CRISPR-Cas9 gene editing technology. The TaCIPK14 knockout mutant shows resistance to inoculation with FHB pathogens, and the results of evaluation of major agronomic traits confirm that the TaCIPK14 knockout mutant reserves the major agronomic traits.

Abstract: Disclosed is a method for remining a residual coal pillar in a residual mining area by collaboration of pillar-side backfilling and in-situ gasification. The method includes the following steps of: ascertaining geological and hydrological conditions, a geometric shape and a reserve of a residual coal pillar; carrying out side supporting on the residual coal pillar in a goaf by using a pillar-side backfilling method; and carrying out the underground gasification mining on the residual coal pillar by means of an underground coal gasification process.

Abstract: A method for recovery of residual coal pillars by freezing accumulated water in room-and-pillar mining areas is provided. A feasibility of repeated mining of residual coal pillars in room-and-pillar goafs is distinguished based on production data and exploration data of a mine. An accumulated water in the room-and-pillar mining areas is frozen to replace a paste filling material, which envelopes collapse roofs and gangues in the room-and-pillar goaf as a whole. The room-and-pillar goaf is filled with a frozen ice body. Roadways and mining faces are arranged in the frozen ice body. Coal cutter cuts the residual coal pillars and the frozen ice body. With the advancing of the mining face, the residual coal pillars are gradually recovered and melted water after the cutting is pumped out.

Abstract: The present disclosure discloses a lakehouse metadata change determination method, an electronic device, and a computer-readable medium. The method includes: for a metadata storage system, after receiving a metadata processing request sent by a data engine and used for requesting to perform update processing on a target object, executing object update processing logic corresponding to the metadata processing request, and after it is determined that the object update processing logic is completed, generating an update description message corresponding to the target object according to a comparison result between the target object before updating and the target object after updating, so that the update description message indicates that the update processing on the target object has been performed, and the update description message can be subsequently sent to a message receiving object.

Abstract: Generating structured query language queries, by extracting database schema from a target database, inputting the database schema into a generative model, training the generative model using a Monte-Carlo method and input data, training a discriminator model to distinguish generated and real input data, determining a loss value for generated input data, further training the generative model using the loss value, receiving, over a network, input text from a user, automatically generating, using the generative model, an output using the input text and providing, over the network, the output to the user.

Abstract: Disclosed is a combined process of integrating stopping-backfilling and carbon storage. The combined process includes the following steps of: determining a cyclic interval of a working face through measured data of a mine pressure of a fully-mechanized coal winning working face; when the stopping distance of the fully-mechanized coal winning working face reaches a backfilling isolation interval, providing a backfilling tarpaulin behind a hydraulic support, and pumping, through a backfilling pipeline, backfilling slurry to a backfilling area along a support beam; when the area is backfilled with the backfilling slurry, injecting supercritical carbon dioxide into the backfilling slurry; and allowing the supercritical carbon dioxide to fully react with the backfilling slurry to solidify the backfilling slurry.

Abstract: An electric-pulse fracturing device for hard roof of coal mine based on a self-sealing water bag and an using method thereof are provided. The device includes a power switch, a charging power supply, a current limiting protection resistor, an energy storage capacitor and a high-voltage electric pulse switch connected in sequence. The energy storage capacitor is connected with an end of a gas gap switch, an other end of the gas gap switch is connected with an assembled self-sealing water bag high-voltage electric pulse electrode structure through a high-voltage cable, and the electrode structure is fixed through an assembly rod. The self-sealing water bag high-voltage electric pulse electrode structure includes a self-sealing water bag and an electrode structure capable of focusing shock wave energy, and the number of the self-sealing water bag high-voltage electric pulse electrode structure depends on fracturing effect.

Abstract: The disclosure discloses a primer for amplifying a molecular marker of powdery mildew resistance gene PmDR754 of Triticum dicoccon Schrank, where the molecular marker primer includes a forward primer HENU765-F and a reverse primer HENU765-R; the nucleotide sequence of the forward primer HENU765-F is shown in SEQ ID NO:1, and the nucleotide sequence of the reverse primer HENU765-R is shown in SEQ ID NO:2. The molecular marker primer provided by the disclosure is applied to detection and identification of gene PmDR754 and auxiliary identification of a wheat powdery mildew resistance trait, and molecular marker-assisted selection breeding.

Abstract: Disclosed is a primer for amplifying a closely linked molecular marker of a powdery mildew resistance gene PmDR803 of Triticum carthlicum. The molecular marker primer includes a forward primer HENU629-F and a reverse primer HENU629-R, where the nucleotide sequence of the forward primer HENU629-F is shown as SEQ ID NO:1, and the nucleotide sequence of the reverse primer HENU629-R is shown as SEQ ID NO:2. The molecular marker primer provided by the present disclosure can be applied in detection and identification of the gene PmDR803, auxiliary identification of a powdery mildew resistance trait of wheat, and molecular marker-assisted selection breeding.

Abstract: A cylindrical battery includes a jelly-roll delectrode assembly with a positive electrode plate. The positive electrode plate includes a current collector, a positive active material layer, and an insulation layer. Both the positive active material layer and the insulation layer are disposed on at least one side of the positive current collector. The positive current collector includes a first region corresponding to the positive active material layer, a second region corresponding to the insulation layer, and a third region covered by neither the positive active material layer nor the insulation layer. The second region is located between the first region and the third region in a width direction of the positive current collector. The insulation layer includes a first part possessing a first width W1 and a second part possessing a second width W2, satisfying: W1+2 mm?W2?W1+10 mm.

Abstract: Provided are a counterweight assembly, a piping system, and an air conditioner. The counterweight assembly includes a counterweight block and a fixing clip. The counterweight block has a clamping hole adapted to a pipe and two separable ends in a circumferential direction of the clamping hole to define an openable slit. The slit is in communication with the clamping hole to allow the pipe to engage into the clamping hole through the slit. The counterweight block has a clamping groove formed on each of outer peripheral walls thereof at two sides of the slit in a circumferential direction of the counterweight block. The clamping grooves are each spaced apart from the slit. The fixing clip has clamping arms respectively adapted to extend into the clamping grooves at two sides of the slits and adapted to be engaged with groove walls of the clamping grooves to close the slit.

Abstract: The present invention discloses an interfering RNA for inhibiting PCSK9 gene and use thereof. The interfering RNA comprises a nucleotide sequence set forth in any one or two or more of SEQ ID NOs: 1-40, 73-96. The interfering RNA of the present invention can better target and silence hepatic PCSK9 mRNA, reduce the protein level of PCSK9, enhance LDL-C metabolism, and reduce serum cholesterol, providing a solid technical foundation for the development of siRNA medicaments for the prevention, treatment, and symptom alleviation of PCSK9 gene-mediated diseases.

Abstract: The present application discloses an access limiting method for a metadata server, an apparatus and a device, wherein the method is applied to a data lake metadata server, receives a metadata access request sent by a client, wherein the request is used for obtaining metadata stored by a storage server for describing target data, and the target data is data in a target table. The metadata service interface used by the data lake metadata server is determined according to the metadata access request. When the metadata service interface satisfies the preset condition, determining the number of applied tokens corresponding to the metadata access request according to the number of table partitions and the number of partition levels of the obtained target table.

Abstract: A lakehouse metadata tag creation method, a lakehouse metadata tag query method and an electronic device are provided. The method includes: after a metadata service gateway determines a metadata tag creation request based on a metadata tag creation parameter provided by a data engine, sending, by the metadata service gateway, the metadata tag creation request to a metadata tag service system, so that the metadata tag service system executes a tag creation logic based on the metadata tag creation parameter carried in the metadata tag creation request, to implement a requirement of tagging one or more pieces of metadata.

Abstract: An embodiment for dynamically generating grayscale release strategies based on multi-objective optimization. The embodiment may define current state vector spaces and an action space for a target system. The embodiment may generate a composite reward function based on one or more objective-based reward functions and one or more constraint-based reward functions. The embodiment may generate, using a first network, candidate action vectors based on the defined current state vector spaces and the defined action space, the candidate action vectors corresponding to action probabilities. The embodiment may calculate, using a second network, state value functions based on the candidate action vectors. The embodiment may execute, in training iterations, actions corresponding to the candidate action vectors to obtain environment feedback including observed rewards. The embodiment may optimize the first and second networks.

Abstract: A data management system, method and computer-readable medium for data integration and quality control are described. In some implementations, a computer-implemented method comprises steps of receiving datasets from one or more data sources, storing the datasets belonging to a domain, checking data integrity of the datasets, performing a quality control check on the datasets, receiving selections from the domain on the datasets that are selected to be processed based on one or more reference libraries, processing one or more selected datasets based on the one or more reference libraries to create mapped data, integrating the mapped data with metadata to provide an integrated analysis, and causing to display, at a graphical user interface (GUI), real-time processing status for each of the one or more selected datasets.