Abstract: An eyeglass frame structure includes a frame, an eyeglass arm pivoting portion disposed separately on both sides of the frame, a lens connecting portion disposed between the eyeglass arm pivoting portions, a U-shaped wind passage formed at each eyeglass arm pivoting portion and having a wind inlet on a windward side of the frame and a wind outlet on a leeward side of the frame for guiding wind transversely to the leeward side of the lens. Eyeglasses with the eyeglass frame structure including two eyeglass arms, two lenses and two nose pads guide wind transversely to the leeward side of the lens to prevent the formation of mists, return air from causing discomfort to wearer's eyes, and tiny objects from entering into the leeward side of the lens. The glasses require no hole or slot formed on the lens, so that the lens structure is not damaged.