Abstract: The present invention provides materials and methods for making a subject non-responsive to an antigen. Methods of the invention may comprise contacting the subject with the antigen and a compound that induces anergy. In some embodiments, the antigen may be an autoimmune antigen, examples of which include, but are not limited to acetylcholine receptor for myasthenia gravis, glutamic acid decarboxylase for type I diabetes mellitus and rheumatoid factor in rheumatoid arthritis. In some embodiments, the present invention provides a method of transplanting an organ, tissue, or cells into a subject (e.g. a mammal such as a human).

Abstract: The present invention provides materials and methods for making a subject non-responsive to an antigen. Methods of the invention may comprise contacting the subject with the antigen and a compound that induces anergy. In some embodiments, the antigen may be an autoimmune antigen, examples of which include, but are not limited to acetylcholine receptor for myasthenia gravis, glutamic acid decarboxylase for type I diabetes mellitus and rheumatoid factor in rheumatoid arthritis. In some embodiments, the present invention provides a method of transplanting an organ, tissue, or cells into a subject (e.g. a mammal such as a human).

Abstract: The present invention provides materials and methods for making a subject non-responsive to an antigen. Methods of the invention may comprise contacting the subject with the antigen and a compound that induces anergy. In some embodiments, the antigen may be an autoimmune antigen, examples of which include, but are not limited to acetylcholine receptor for myasthenia gravis, glutamic acid decarboxylase for type I diabetes mellitus and rheumatoid factor in rheumatoid arthritis. In some embodiments, the present invention provides a method of transplanting an organ, tissue, or cells into a subject (e.g. a mammal such as a human).

Abstract: The present invention provides materials and methods for making a subject non-responsive to an antigen. Methods of the invention may comprise contacting the subject with the antigen and a compound that induces anergy. In some embodiments, the antigen may be an autoimmune antigen, examples of which include, but are not limited to acetylcholine receptor for myasthenia gravis, glutamic acid decarboxylase for type I diabetes mellitus and rheumatoid factor in rheumatoid arthritis. In some embodiments, the present invention provides a method of transplanting an organ, tissue, or cells into a subject (e.g. a mammal such as a human).

Abstract: A game device includes an owned card storage unit for storing player cards owned by a game player, and a player card exchange unit for exchanging a player card owned by the game player with an exchangeable card presented by a CPU, wherein the player card exchange unit includes an exchangeable card presentation unit for determining the exchangeable cards based on the player cards owned by the game player to be presented on a screen, an exchange condition presentation unit for setting an exchange condition for exchanging the exchangeable card with the player card owned by the game player to be presented on the screen; and an exchange execution unit for approving the exchange of the player card and the exchangeable card when the player card that satisfies the exchange condition is selected by the game player, and updating the memory content of the owned card storage unit to a content after the approval of the exchange.

Abstract: A tumor marker comprising diacetylspermine, and a method of evaluating the state of a tumor, comprising reacting an antibody to diacetylspermine with a biological sample to thereby detect diacetylspermine and evaluating the state of the tumor using the obtained detection results as an indicator.

Abstract: A manager evaluation value setting unit sets a manager evaluation value indicating a management ability of a manager character to manage player characters. A player evaluation value setting unit sets a player evaluation value used to evaluate the player character according to an ability value indicating an ability of the player character. An evaluation difference value calculating unit calculates an evaluation difference value indicating a difference between the manager evaluation value and the player evaluation value when the manager evaluation value is lower than the player evaluation value. A management ability setting unit changes the manager evaluation value to reduce the management ability of the manager character as the evaluation difference value increases.

Abstract: A game device includes an owned card storage unit for storing player cards owned by a game player, and a player card exchange unit for exchanging a player card owned by the game player with an exchangeable card presented by a CPU, wherein the player card exchange unit includes an exchangeable card presentation unit for determining the exchangeable cards based on the player cards owned by the game player to be presented on a screen, an exchange condition presentation unit for setting an exchange condition for exchanging the exchangeable card with the player card owned by the game player to be presented on the screen; and an exchange execution unit for approving the exchange of the player card and the exchangeable card when the player card that satisfies the exchange condition is selected by the game player, and updating the memory content of the owned card storage unit to a content after the approval of the exchange.

Abstract: The present invention provides materials and methods for modulating an immune response. The materials and methods may be used to treat diseases associated with an aberrant immune response. In some embodiments, materials and methods of the invention may be used to treat autoimmune diseases, for example, rheumatoid arthritis.

Abstract: A plant cultivation method of the present invention includes the steps of: placing a plant under a condition at a pressure of not less than 1.5 atmospheres and not more than 10 atmospheres; and cultivating the plant. A plant cultivation device (1) includes: a cultivation chamber (10); and a compressor (20) which supplies compressed air into the cultivation chamber. A carry-in opening (30), which is provided on a side wall (16) of the cultivation chamber (10) so that a material is carried in/out to/from the cultivation chamber (10) via the carry-in opening (30), is provided with a cover (31) which has a shape that is hemispherical and protrudes toward an inside of the cultivation chamber (10). The cover (31) closes the carry-in opening (30) by being in contact, via a packing (32), with an inner surface of the side wall (16) surrounding the carry-in opening (30).

Abstract: A gaming device includes a release pattern prediction section which determines a prediction release pattern for the release pattern of the flying object to be released by the first personified character by selecting one of the plurality of release patterns stored in the release pattern storing section based on a selecting operation by a user operating the second personified character; and a difficulty adjustment section, which compares the release pattern determined with the prediction release pattern, and reduces the difficulty for the second character to hit back the flying object released by the first character when the release pattern determined and the prediction release pattern match.

Abstract: The present invention provides materials and methods for making a subject non-responsive to an antigen. Methods of the invention may comprise contacting the subject with the antigen and a compound that induces anergy. In some embodiments, the antigen may be an autoimmune antigen, examples of which include, but are not limited to acetylcholine receptor for myasthenia gravis, glutamic acid decarboxylase for type I diabetes mellitus and rheumatoid factor in rheumatoid arthritis, hi some embodiments, the present invention provides a method of transplanting an organ, tissue, or cells into a subject (e.g., a mammal such as a human).

Abstract: A gateway device includes a base processor which converts a signal input from an IP network to a signal which can be handled by the gateway device, and a home appliance control processor having a controller which converts the signal which can be handled by the gateway device to a control signal in compliance with the communications protocol of a home appliance to be controlled. The controller stores, on a table, information about the communications protocol, driver, controllable setting condition and status of respective appliances to be controlled in association with each other. The controller also includes a conversion functional block which converts information supplied to the control information of the communications protocol of the respective appliances to be controlled on the basis of the stored information.

Abstract: A manager evaluation value setting unit sets a manager evaluation value indicating a management ability of a manager character to manage player characters. A player evaluation value setting unit sets a player evaluation value used to evaluate the player character according to an ability value indicating an ability of the player character. An evaluation difference value calculating unit calculates an evaluation difference value indicating a difference between the manager evaluation value and the player evaluation value when the manager evaluation value is lower than the player evaluation value. A management ability setting unit changes the manager evaluation value to reduce the management ability of the manager character as the evaluation difference value increases.

Abstract: The present invention provides materials and methods for modulating an immune response. The materials and methods may be used to treat diseases associated with an aberrant immune response. In some embodiments, materials and methods of the invention may be used to treat autoimmune diseases, for example, rheumatoid arthritis.

Abstract: A main controller used in a security system having a sensor or a camera performs wireless communication with the sensor or the camera so as to control the sensor or the camera. The main controller has a plurality of communication sections that perform wireless communication by using communication systems having different communication speeds. The camera transmits and receives information by performing wireless communication with the main controller. The camera is provided with a first camera communication section and a second camera communication section that perform wireless communication by using communication systems having different communication speeds, and a camera communication control section for selecting the first camera communication section and the second camera communication section according to the information to be transmitted and received, as a communication section to perform communication.

Abstract: A tumor marker comprising diacetylspermine, and a method of evaluating the state of a tumor, comprising reacting an antibody to diacetylspermine with a biological sample to thereby detect diacetylspermine and evaluating the state of the tumor using the obtained detection results as an indicator.

Abstract: Compounds are described which modulate the tzrosine kinase activity of p56lck and signal transduction pathways in which this enzyme is involved. The invention also relates to compounds which have immunomodulatory activity, e.g., which have immunosuppressant or immunostimulatory activity, and/or which have an antineoplastic effect. The invention further relates to compositions comprising these compounds, and methods of using them. Compounds are described which modulate the tyrosine kinase activity of p56.

Abstract: A gateway device includes a base processor which converts a signal input from an IP network to a signal which can be handled by the gateway device, and a home appliance control processor having a controller which converts the signal which can be handled by the gateway device to a control signal in compliance with the communications protocol of a home appliance to be controlled. The controller stores, on a table, information about the communications protocol, driver, controllable setting condition and status of respective appliances to be controlled in association with each other. The controller also includes a conversion functional block which converts information supplied to the control information of the communications protocol of the respective appliances to be controlled on the basis of the stored information.

Abstract: Small molecular-weight non-peptidic compounds block Lck SH2 domain-dependent interactions. The inhibitors omit phosphotyrosine (pY) or related moieties.