Patents by Inventor Jun Hiyama

Jun Hiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for the Treatment and Prevention of Neoplastic Disorders
    Publication number: 20080145313
    Abstract: Compositions for the treatment and/or prevention of cancer in a mammal by means of RNA interference are provided, together with methods for the use of such compositions. The compositions comprise a small interfering nucleic acid molecule (siNA) that suppresses expression of a target gene that: (a) is involved in an energy metabolism pathway, such as the glycolysis pathway, within a tumor cell; (b) is involved in the biosynthesis of nucleotides, in glycogen metabolism or is an electron carrier that works with ATP to provide metabolic energy; or (c) is involved in transport of sugars, amino acids, and/or water-soluble vitamins, control of intercellular pH, or drug transport within a tumor cell.
    Type: Application
    Filed: August 30, 2007
    Publication date: June 19, 2008
    Applicant: Genesis Research & Development Corporation Limited
    Inventors: James D. Watson, Elizabeth S. Visser, Jun Hiyama, llkka J. Havukkala, Glen Reid, Annette Lasham
  • Compounds and methods for treatment and diagnosis of mycobacterial infections
    Patent number: 6410720
    Abstract: The present invention provides polypeptides comprising an immunogenic portion of a M. vaccae soluble protein and DNA molecules encoding such polypeptides, together with methods for their use in the diagnosis and treatment of mycobacterial infection. Methods for enhancing the immune response to an antigen including administration of M. vaccae culture filtrate or delipidated M. vaccae cells are also provided.
    Type: Grant
    Filed: November 5, 1998
    Date of Patent: June 25, 2002
    Assignee: Genesis Research & Development Corp. Ltd.
    Inventors: Paul Tan, Jun Hiyama
  • Compounds and methods for treatment and diagnosis of mycobacterial infections
    Patent number: 6284255
    Abstract: The present invention provides polypeptides comprising an immunogenic portion of a M. vaccae soluble protein and DNA molecules encoding such polypeptides, together with methods for their use in the diagnosis and treatment of mycobacterial infection. Methods for enhancing the immune response to an antigen including administration of M. vaccae culture filtrate or delipidated M. vaccae cells are also provided.
    Type: Grant
    Filed: August 29, 1996
    Date of Patent: September 4, 2001
    Assignee: Genesis Research & Development Corporation Limited
    Inventors: Paul Tan, Jun Hiyama, Elizabeth Visser, Linda Scott
  • Mycobacterium vaccae antigens
    Patent number: 6001361
    Abstract: The present invention provides polypeptides comprising an immunogenic portion of a M. vaccae soluble protein and DNA molecules encoding such polypeptides, together with methods for their use in the diagnosis and treatment of mycobacterial infection. Methods for enhancing the immune response to an antigen including administration of M. vaccae culture filtrate or delipidated M. vaccae cells are also provided.
    Type: Grant
    Filed: June 12, 1997
    Date of Patent: December 14, 1999
    Assignee: Genesis Research & Development Corporation Limited
    Inventors: Paul Tan, Jun Hiyama, Elizabeth Visser, Margot Skinner, Linda Scott, Ross Prestidge