Abstract: This disclosure relates to a population of interferon (IFN)-enhanced chimeric antigen receptor (CAR)-T cells and methods of their production. The methods include treating a population of CAR-T cells expressing a CAR gene construct with a concentration of an IFN receptor agonist sufficient to produce a population of IFN-enhanced CAR-T cells, wherein compared to an untreated control CAR-T cell population, the population of IFN-enhanced CAR-T cells exhibits increased expression of one or more interferon-stimulated genes. The disclosure also relates to a pharmaceutical composition comprising the population of IFN-enhanced chimeric antigen receptor (CAR)-T cells and methods of treating cancer with the pharmaceutical composition.

Abstract: In an audio processing method, an initial audio feature of initial audio data is obtained. The initial audio feature is input to an audio enhancement model. The audio enhancement model is iteratively trained based on a deep clustering loss function and a mask inference loss function. Target audio data with reduced noise and reverberation is calculated according to a target audio feature. The target audio feature is generated by the audio enhancement model based on the initial audio feature. The target audio data is output.

Abstract: The present application belongs to the technical field of communications. Disclosed are a sensing signal transmission method, an electronic device, and a storage medium. The transmission method comprises: transmitting a sequence of sensing signals by means of at least two first orthogonal frequency division multiplexing (OFDM) symbols in a signal sequence, wherein the at least two first OFDM symbols are prior to a second OFDM symbol in the signal sequence, there is no second OFDM symbol between the at least two first OFDM symbols, the first OFDM symbols are used for performing downlink sending or performing switching between downlink transmission and uplink transmission, and the second OFDM symbol is used for performing uplink reception.

Abstract: The amino acid sequence of a w-transaminase mutant derived from mutation of ?-transaminase from Aspergillus terreus, is as shown in SEQ ID NO. 4 or SEQ ID NO. 6. Compared with the wild-type enzyme, the half-lives of the ?-transaminase mutants are all above 24 h, while the half-life of the wild-type is only 6.90 min. The half-inactivation temperature of the mutants are 49.00° C. and 49.03° C., respectively, which are about 11° C. higher than that of the wild-type (37.89° C.), such that the thermal stability is significantly improved.

Abstract: The present disclosure presents a device and method for monitoring and early warning of information perception regarding urban yellow mud water, featuring a rainfall collecting component, a video shooting component, a sediment content monitoring component, a water level monitoring component and a main controller. The video shooting component evaluates the long-term trend of yellow mud water production in a monitoring area by analyzing the color depth of captured water flow, sediment content in the pipeline's flow section, and meteorological rainfall data from the rainfall collecting component. Utilizing data on color, sediment content, flow section, and rainfall, this system achieves unsupervised real-time monitoring and precise early warning for yellow mud water. It provides a scientific basic for traceability, dynamic monitoring, and address challenges such as low measurement accuracy and omitted applicability found in existing methods.

Abstract: Methods, systems, and devices related to host identification for a memory system are described. A memory system may receive an index value from a host system that is associated with an identification of the host system. The memory system may identify one or more operating parameter associated with the index value based on receiving the index value. The memory system controller may configure the memory system to utilize one or more operating parameters associated with the index value based on identifying the operating parameters. The memory system may output an indication to the host system that the operating parameters associated with the index value are configured to be utilized by the memory system.

Abstract: Provided is a method for immunotherapy of colorectal cancer (CRC), including administering to a subject in need at least one selected from the group consisting of (a) a gut microbiota or a metabolite thereof and (b) an antibody or a derivative thereof. The gut microbiota includes at least one selected from the group consisting of Alistipes shahii, Butyricimonas virosa, Desulfovibrio piger, Alistipes putredinis, Odoribacter splanchnicus, Faecalibacterium prausnitzii, Phocaeicola plebeius, Eubacterium rectale, Oscillospiraceae bacterium, and Alistipes onderdonkii. The gut microbiota or the metabolite thereof and/or the antibody or the derivative thereof in this application can increase the anti-tumor effect of immunotherapy, and demonstrate the functions of regulating the immune microenvironment and improving sensitivity to tumor immunotherapy.

Abstract: A method is provided for measuring the impedance of a pH sensor electrode. The method includes applying a positive voltage pulse to the pH electrode and taking a plurality of samples of the sensor voltage response and, from those samples, estimating the impedance of the sensor electrode. Then, a negative voltage pulse width is dynamically adjusted to cancel out the induced charges from the positive voltage on the pH sensor so that the sensor quickly recovers to read subsequent media pH levels.

Abstract: Provided is a a semiconductor laser module, comprising, from bottom to top, a substrate, a lower limiting layer, a lower waveguide layer, an active layer, an upper waveguide layer, an electron blocking layer, and an upper limiting layer. The active layer satisfies at least one of that a content ratio of an element Al to an element H satisfies a first preset proportion distribution, a content ratio of an element In to the element H satisfies a second preset proportion distribution, a content ratio of an element Si to the element H satisfies a third preset proportion distribution, a content ratio of an element Mg to the element H satisfies a fourth preset proportion distribution, and a content ratio of an element C to an element O satisfies a fifth preset proportion distribution.

Abstract: Methods, systems, and devices that support a dynamic screen refresh rate are described. An electronic device may dynamically (e.g., autonomously, while operating) adjust the rate at which a screen is refreshed, such as to balance considerations such as user experience and power consumption by the electronic device. For example, the electronic device may use an increased refresh rate when executing applications for which user experience is enhanced by a higher refresh rate and may use a decreased refresh rate when executing other applications. As another example, the electronic device may use different refresh rates while executing different portions of the same application, as some aspects of an application (e.g., more intense portions of a video game) may benefit more than others from a higher refresh rate. The electronic device may also account of rother factors, such as battery level, when setting or adjusting the refresh rate of the screen.

Abstract: Embodiments of the present disclosure provide a method and apparatus for estimating an angle of arrival of a channel Sounding Reference Signal (SRS). By means of the present disclosure, a plurality of passive antennas receive, in a time-division manner, SRSs configured at a specified comb position, then a same active antenna channel amplifies and samples the SRSs received by the plurality of passive antennas, and the amplified and sampled SRSs are segmented, and angles of arrival of the SRSs are estimated based on each segment of the SRSs.

Abstract: Systems, devices, media, and methods are presented for assigning configuration parameters to unknown devices by comparing characteristics of unknown devices to characteristics of known devices. Characteristics of an unknown device are compared to characteristics of known devices to identify a similar device having known configuration parameters. The unknown device is then assigned the configuration parameters of the identified similar device.

Abstract: Flexible optical fiber ribbon includes multiple optical fibers. The multiple optical fibers are optical fibers arranged side by side, and multiple bonded portions are arranged between adjacent optical fibers and distributed intermittently along the longitudinal direction, the multiple bonded portions being made of the same material; each optical fiber has a ink layer at the underlying outermost layer and a transparent coating layer at the outermost layer; the transparent coating layers of the multiple optical fibers are made of the same material, and the transparent coating layers are continuous in the axial direction and continuous in the circumferential direction; the colors and/or shapes of the ink layers of optical fibers are observed through the transparent coating layers, and there is at least one optical fiber, among the multiple optical fibers, of which the color and/or shape of the ink layer thereof is different from that of another optical fiber among the multiple optical fibers.

Abstract: The disclosure provides a display apparatus and a data processing method. The display apparatus detects a media resource type of a target program in response to a recording command for the target program. The media resource type includes a network media resource and a non-network media resource. Based on that the media resource type is the network media resource, the display apparatus downloads media resource data of the target program according to the resource locator address and writes the media resource data onto a memory; and based on that the media resource type is the non-network media resource, the display apparatus searches for a target network media resource corresponding to the target program, and downloads media resource data of the target program according to the resource locator address and writes the media resource data onto the memory based on that the target program has the target network media resource.

Abstract: The present disclosure provides a head mounted display includes a display assembly to display a compensated image, an imaging assembly to modulate the compensated image into a near-to-eye image and projects the near-to-eye image to a user's eye, a driving device connects with the imaging assembly for adjusting a position of the imaging assembly, an eye tracking device to obtain an outline image of the eye, and a processor. The processor electrically connects with the eye tracking device and the driving device to calculate a gaze position of the eye on the display assembly according to the outline image, and is used to transmit a control signal to the driving device to make the driving device adjust a position of the imaging assembly according to the control signal, so that an optical axis of the image module coincides with the gaze position. The processor also electrically connects with the display assembly to generate the compensated image centered on the gaze position.

Abstract: System, method, and various embodiments for a chatbot event generation system are described herein. An embodiment operates by receiving a request to create an event, and identifying a set of parameters associated with generating the event. A first subset of parameters as provided with the request are identified. A prompt for a large language model (LLM) is generated, and a second subset of parameters is received from the LLM. The event is generated based on the first subset of parameters provided with the request and the second subset of parameters provided by the LLM. The event is detected and an additional action is performed responsive to the detecting the event.

Abstract: Methods, systems, and devices related to host identification for a memory system are described. A memory system may receive an index value from a host system that is associated with an identification of the host system. The memory system may identify one or more operating parameter associated with the index value based on receiving the index value. The memory system controller may configure the memory system to utilize one or more operating parameters associated with the index value based on identifying the operating parameters. The memory system may output an indication to the host system that the operating parameters associated with the index value are configured to be utilized by the memory system.

Abstract: Embodiments of the present disclosure provide a semiconductor laser component, comprising, from bottom to top, a substrate, a lower limiting layer, a lower waveguide layer, an active layer, an upper waveguide layer, an electron blocking layer, and an upper limiting layer. The active layer satisfies at least one of that a content ratio of an element Al to an element H satisfies a first preset proportion distribution, a content ratio of an element In to the element H satisfies a second preset proportion distribution, a content ratio of an element Si to the element H satisfies a third preset proportion distribution, a content ratio of an element Mg to the element H satisfies a fourth preset proportion distribution, and a content ratio of an element C to an element O satisfies a fifth preset proportion distribution.

Abstract: A sugar-reduced sweetener can be a high-intensity sweetener, a bulk sweetener, or a one sugar sweetener. The dosages of the high-intensity sweetener and the bulk sweetener satisfy a condition that the sweetness of the two compounded approaches to that of the sugar sweetener. Flavor, sweetness, taste and efficacy of original sugar sweet substances, for example, common sugar varieties in life such as sucrose and brown sugar can be reserved, and the sugar-reduced sweetener can replace sucrose perfectly. During use, according to the requirements of the sugar reduction ratio, the sugar sweetening substances can be added in any proportion, which can greatly reduce the sugar content so as to achieve the purpose of lowering and reducing sugar. In a preparation method of the sugar-reduced sweetener of the present invention, an intermittent spraying method is adopted, so that the quality of a final product is stable.

Abstract: Methods, systems, and devices that support a dynamic screen refresh rate are described. An electronic device may dynamically (e.g., autonomously, while operating) adjust the rate at which a screen is refreshed, such as to balance considerations such as user experience and power consumption by the electronic device. For example, the electronic device may use an increased refresh rate when executing applications for which user experience is enhanced by a higher refresh rate and may use a decreased refresh rate when executing other applications. As another example, the electronic device may use different refresh rates while executing different portions of the same application, as some aspects of an application (e.g., more intense portions of a video game) may benefit more than others from a higher refresh rate. The electronic device may also account of rother factors, such as battery level, when setting or adjusting the refresh rate of the screen.