Patents by Inventor Jun Kotera

Jun Kotera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PREVENTION OR TREATMENT OF MYOPATHY USING MIR-33B INHIBITOR
    Publication number: 20240240176
    Abstract: A prophylactic or therapeutic agent for a myopathy, including a miR-33b inhibitor, preferably an antisense oligonucleotide against miR-33b, as an effective component.
    Type: Application
    Filed: April 28, 2022
    Publication date: July 18, 2024
    Applicants: KYOTO UNIVERSITY, OSAKA UNIVERSITY
    Inventors: Jun KOTERA, Koh ONO, Takahiro HORIE, Naoya SOWA, Yuya IDE, Satoshi OBIKA, Yuya KASAHARA
  • PREVENTION OR TREATMENT OF ANEURYSMS USING MIR-33B INHIBITOR
    Publication number: 20230159924
    Abstract: A prophylactic or therapeutic agent for an aneurysm comprising a miR-33b inhibiting substance, preferably an antisense oligonucleotide against miR-33b, as an active ingredient.
    Type: Application
    Filed: March 2, 2021
    Publication date: May 25, 2023
    Applicants: MITSUBISHI TANABE PHARMA CORPORATION, KYOTO UNIVERSITY, OSAKA UNIVERSITY, NATIONAL INSTITUTES OF BIOMEDICAL INNOVATION, HEALTH AND NUTRITION
    Inventors: Jun KOTERA, Koh ONO, Takahiro HORIE, Tomohiro YAMASAKI, Satoshi KOYAMA, Satoshi OBIKA, Yuya KASAHARA
  • Treatment of Parkinson's disease and enhancement of dopamine signal using PDE 10 inhibitor
    Patent number: 8338420
    Abstract: The present invention relates to a therapeutic or prophylactic method for treating Parkinson's disease by administering an effective amount of a compound having a phosphodiesterase 10 inhibitory activity; and also relates to a pharmaceutical composition for treatment or prophylaxis of Parkinson's disease comprising as an active ingredient a compound having a phosphodiesterase 10 inhibitory activity. Moreover, the present invention relates to a method for enhancing dopamine signal in the brain, which comprises administering an effective amount of a compound having a phosphodiesterase 10 inhibitory activity; and also relates to pharmaceutical composition for enhancing dopamine signal in brain comprising as an active ingredient a compound having a phosphodiesterase 10 inhibitory activity.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: December 25, 2012
    Assignee: Mitsubishi Tanabe Pharma Corporation
    Inventors: Jun Kotera, Takashi Sasaki, Takeo Kitazawa, Taketoshi Ishii, Hiroshi Morimoto, Harutami Yamada
  • Phosphodiesterase and gene thereof
    Patent number: 8012731
    Abstract: The present invention is to provide a novel phosphodiesterase and a gene thereof, specifically, Type 11 phosphodiesterase (PDE11) and a gene thereof, more specifically, a phosphodiesterase selected from (A) a protein having an amino acid sequenced shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39, and (B) a protein having an amino acid sequence shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39 in which one or several amino acids are deleted, substituted or added, and having an activity of hydrolyzing a cyclic nucleotide, and a gene thereof, and a method of characterizing, identifying and selecting a phosphodiesterase inhibitor by using the same.
    Type: Grant
    Filed: December 20, 2007
    Date of Patent: September 6, 2011
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Kenji Omori, Keizo Yuasa, Jun Kotera, Kotomi Oda, Hideo Michibata
  • NOVEL PHOSPHODIESTERASE AND GENE THEREOF
    Publication number: 20090325207
    Abstract: The present invention is to provide a novel phosphodiesterase and a gene thereof, specifically, Type 11 phosphodiesterase (PDE11) and a gene thereof, more specifically, a phosphodiesterase selected from (A) a protein having an amino acid sequenced shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39, and (B) a protein having an amino acid sequence shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: in which one or several amino acids are deleted, substituted or added, and having an activity of hydrolyzing a cyclic nucleotide, and a gene thereof, and a method of characterizing, identifying and selecting a phosphodiesterase inhibitor by using the same.
    Type: Application
    Filed: December 20, 2007
    Publication date: December 31, 2009
    Applicant: MITSUBISHI TANABE PHARMA CORPORATION
    Inventors: Kenji OMORI, Keizo Yuasa, Jun Kotera, Kotomi Oda, Hideo Michibata
  • Phosphodiesterase and genes thereof
    Patent number: 7332317
    Abstract: The present invention is to provide a novel phosphodiesterase and a gene thereof, specifically, Type 11 phosphodiesterase (PDE11) and a gene thereof, more specifically, a phosphodiesterase selected from (A) a protein having an amino acid sequenced shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39, and (B) a protein having an amino acid sequence shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39 in which one or several amino acids are deleted, substituted or added, and having an activity of hydrolyzing a cyclic nucleotide, and a gene thereof, and a method of characterizing, identifying and selecting a phosphodiesterase inhibitor by using the same.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: February 19, 2008
    Assignee: Tanabe Seiyaku Co., Ltd.
    Inventors: Kenji Omori, Keizo Yuasa, Jun Kotera, Kotomi Oda, Hideo Michibata
  • Novel phosphodiesterase and genes thereof
    Publication number: 20030190672
    Abstract: The present invention is to provide a novel phosphodiesterase and a gene thereof, specifically, Type 11 phosphodiesterase (PDE11) and a gene thereof, more specifically, a phosphodiesterase selected from (A) a protein having an amino acid sequenced shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39, and (B) a protein having an amino acid sequence shown by SEQ.ID.NO: 2, SEQ.ID.NO: 4, SEQ.ID.NO: 6 or SEQ.ID.NO: 39 in which one or several amino acids are deleted, substituted or added, and having an activity of hydrolyzing a cyclic nucleotide, and a gene thereof, and a method of characterizing, identifying and selecting a phosphodiesterase inhibitor by using the same.
    Type: Application
    Filed: June 21, 2002
    Publication date: October 9, 2003
    Inventors: Kenji Omori, Keizo Yuasa, Jun Kotera, Kotomi Oda, Hideo Michibata