Abstract: Disclosed in the present invention is a new triptolide derivative as shown in formula (I). Also disclosed in the present invention are a preparation method for the compound and the medical use thereof in preparation of anti-cancer drugs. Triptolide acrylate of the present invention and a pharmaceutically acceptable salt thereof have anti-cancer activity, and after animal in-vivo experiments, can effectively inhibit tumor growth in animals. A plurality of in-vitro experiments proves that same can significantly increase the protein expression quantity of p53, promote the apoptosis of tumor cells, effectively inhibit the growth of the tumor cells, and have the effect of inhibiting metastasis of cancer cells. More importantly, the toxicity of the compound to normal cells is less than that of triptolide.

Abstract: Disclosed in the present disclosure is an FPGA implementation device and method for an FBLMS algorithm based on block floating point. The method includes: blocking, caching, and reassembling a reference signal, by an input caching and converting module, converting into a block floating point system and performing FFT; filtering, by a filtering module, in a frequency domain and performing dynamic truncation; caching, by an error calculating and output caching module, a target signal on a block basis, converting into a block floating point system, subtracting an output result output from the filtering module from the converted target signal to obtain an error signal, converting the error signal into a fixed point system to obtain a final cancellation result; obtaining, by a weight adjustment amount calculating module and a weight updating and storing module, an adjustment amount of a frequency domain block weight and updating the frequency domain block weight.

Abstract: Disclosed are compositions for treating and conditioning keratinous substrates, comprising a cationic agent comprising quaternary ammonium compounds; a modified starch; silane compounds, a cationic vinylpyrrolidone polymer and water. Also disclosed are methods treating and conditioning keratinous substrates using the composition.

Abstract: An apparatus including processing circuitry and a method are described. When receiving a cross-chain transaction request to transfer a resource from a first account to a second account, the processing circuitry is configured to generate a task corresponding to the first account. The task can indicate conditions for implementing events in transferring the resource. A first blockchain system provides services for the first account, and a second blockchain system different from the first blockchain system provides services for the second account. The processing circuitry transfers the resource to the second account based on the task when a first plurality of first nodes in the first blockchain system reaches a consensus on a generation event of the task and updates a task status of the task to being finished when a plurality of second nodes in the second blockchain system reaches a consensus on a transfer event of the resource.

Abstract: A memory temperature controlling method and a memory temperature controlling system are provided. The method includes: performing, by a testing equipment, test modes on a memory storage device, and obtaining a first internal temperature of a memory control circuit unit, a second internal temperature of each memory package and a surface temperature of each memory package to establish a linear relationship expression of the first internal temperature, the second internal temperature and the surface temperature; using, by the memory storage device, the linear relationship expression to calculate a predicted surface temperature of a rewritable non-volatile memory based on a first current internal temperature of the memory control circuit unit and a second current internal temperature of each memory package; adjusting, by the memory storage device, an operating frequency for accessing the rewritable non-volatile memory based on the predicted surface temperature.

Abstract: A system for treating tin smelting intermediate materials and method for treating the materials is disclosed. The system includes a fuming furnace, an electric settling furnace, a lean slag water quenching pool, a matte ladle, a pulverized coal injection system, a flue gas treatment system and a secondary air supply system; the fuming furnace is connected with the electric settling furnace, the pulverized coal injection system, the flue gas treatment system and the secondary air supply system respectively; the electric settling furnace is also connected with the slag-lean water quenching pool and the matte ladle respectively. The system and method disclosed by the disclosure can efficiently classify, separate and recover tin from other materials, solve the problems of difficult sales and transportation of complex tin-containing smelting intermediate materials and economic loss of discounted sales, and transform hazardous wastes into value-added valuable materials for comprehensive recovery.

Abstract: An electronic device coupled to a display includes a graphics card and a processor. The graphics card reads the extended display identification data from the display. The processor determines, according to the extended display identification data, that the display is able to display a default resolution at a first refresh rate at most, and determines, according to the extended display identification data, whether the display device is able to display the default resolution at a second refresh rate that exceeds the first refresh rate. When it is determined that the display is able to display the default resolution at the second refresh rate, the processor adds the second refresh rate into the extended display identification data.

Abstract: The present invention provides an antenna structure for metal environment. The antenna structure comprises a radiating conductor, a first ground conductor, and a second ground conductor. The radiating conductor comprises a first opening circuit, and a second opening circuit, in which the first opening circuit is opened at a first side of the radiating conductor, and the second opening circuit is opened at a second side of the radiating conductor. The first ground conductor is electrically coupled to a third side of the radiating conductor while the second ground conductor is electrically coupled to a fourth side of the radiating conductor. Alternatively, the present invention further provides an antenna device by folding the antenna structure having RFID chip electrically attached thereon to cover a substrate, whereby the antenna device could be accessed in a metal environment.

Abstract: 3-Carbonylamino-8-aminoisoquinoline compounds of formula (I): variations thereof, and their use as inhibitors of HPK1 (hematopoietic kinase 1) are described. The compounds are useful in treating HPK1-dependent disorders and enhancing an immune response. Also described are methods of inhibiting HPK1, methods of treating HPK1-dependent disorders, methods for enhancing an immune response, and methods for preparing the 3-carbonylamino-8-aminoisoquinoline compounds.

Abstract: The field of high-speed data acquisition and network data processing, and particularly relates to an Ethernet data stream recording method, an Ethernet data stream recording system, and an Ethernet data stream recording device for a high-speed data acquisition system. It is intended to solve problems such as a low utilization rate of CPU, poor system compatibility, difficulty in packaging and deployment and low reliability of system transmission of the traditional high-speed data acquisition system.

Abstract: The present disclosure provides a direction adjustable LED lamp used in a sign, which includes a lamp body, two lamp holders arranged on an upper end and a lower end of the lamp body respectively, a plurality of LED modules installed on a surface of the lamp body, an outer casing installed in the lamp body, a buffer column installed on a surface of the outer casing, an isolated constant current driver installed in the outer casing, the lamp body defines a limit groove closing to the LED modules, and a horizontal plate is installed in the limit groove.

Abstract: Various lactam compound that binds Cbl-B, many of which are selective for Cbl-B over C-Cbl, and methods of making and using the same.

Abstract: A memory temperature controlling method and a memory temperature controlling system are provided. The method includes: performing, by a testing equipment, test modes on a memory storage device, and obtaining a first internal temperature of a memory control circuit unit, a second internal temperature of each memory package and a surface temperature of each memory package to establish a linear relationship expression of the first internal temperature, the second internal temperature and the surface temperature; using, by the memory storage device, the linear relationship expression to calculate a predicted surface temperature of a rewritable non-volatile memory based on a first current internal temperature of the memory control circuit unit and a second current internal temperature of each memory package; adjusting, by the memory storage device, an operating frequency for accessing the rewritable non-volatile memory based on the predicted surface temperature.

Abstract: A memory thermal throttling method and a memory thermal throttling system are provided. The method includes: performing, by a testing equipment, test modes on a memory storage device, and obtaining an internal temperature of a memory control circuit unit, a work loading of each memory package and a surface temperature of each memory package to establish a linear relationship between the work loading, the internal temperature, and the surface temperature; storing, by the testing equipment, the linear relationship in the memory storage device; using, by the memory storage device, the linear relationship based on a current internal temperature of the memory control circuit unit and a current work loading of a first memory package of the memory packages to calculate a predicted surface temperature of the first memory package; adjusting, by the memory storage device, an operating frequency for accessing the first memory package based on the predicted surface temperature.

Abstract: Embodiments of methods and apparatus for reducing warpage of a substrate are provided herein. In some embodiments, a method for reducing warpage of a substrate includes: applying an epoxy mold over a plurality of dies on the substrate in a dispenser tool; placing the substrate on a pedestal in a curing chamber, wherein the substrate has an expected post-cure deflection in a first direction; inducing a curvature on the substrate in a direction opposite the first direction; and curing the substrate by heating the substrate in the curing chamber.

Abstract: Described herein are tetrahydro-pyrido[3,4-b]indol-1-yl compounds with estrogen receptor modulation activity or function having the Formula I structure: and stereoisomers, tautomers, or pharmaceutically acceptable salts thereof, and with the substituents and structural features described herein. Also described are pharmaceutical compositions and medicaments that include the Formula I compounds, as well as methods of using such estrogen receptor modulators, alone and in combination with other therapeutic agents, for treating diseases or conditions that are mediated or dependent upon estrogen receptors.

Abstract: Isoquinoline compounds and their use as inhibitors of HPK1 (hematopoietic kinase 1) are described. The compounds are useful in treating HPK1-dependent disorders and enhancing an immune response. Also described are methods of inhibiting HPK1, methods of treating HPK1-dependent disorders, methods for enhancing an immune response, and methods for preparing the isoquinoline compounds.

Abstract: A transaction data processing method includes: receiving a first transaction document from a device of a transaction initiator, the first transaction document being associated with identity labels of a plurality of transaction participants; separately performing identity authentication on the plurality of transaction participants according to the identity labels of the plurality of transaction participants, to obtain an identity authentication result.

Abstract: Methods and apparatus for processing a substrate are provided. For example, metrology apparatus configured for use with a substrate processing platform comprise an interferometer configured to obtain a first set of measurements at a first set of points along a surface of a substrate, a sensor configured to obtain a second set of measurements at a second set of points different from the first set of points along the surface of the substrate, an actuator configured to position the interferometer and the sensor at various positions along a measurement plane parallel to the surface of the substrate for obtaining the first set of measurements and the second set of measurements, and a substrate support comprising a substrate support surface for supporting the substrate beneath the measurement plane while obtaining the first set of measurements and the second set of measurements.

Abstract: A hair treatment compositions including about 20 wt. % or more of a polyol; about 5 wt. % to about 50 wt. % of a monoalcohol having 1 to 10 carbons; about 0.1 to about 5 wt. % of silicone; about 0.1 to about 10 wt. % of a cationic polymer; about 0.1 to about 10 wt. % of a cationic surfactant; about 0.1 to about 15 wt. % of a fatty alcohol; and about 10 wt. % or less of water, wherein all percentages by weight are based on the total weight of the hair treatment composition.