Abstract: There is provided an optical recording medium, in which a light transmitting layer is formed on a disc substrate, having less deflection and being excellent in recording/reproducing properties. In an optical disc, an information signal area on which an information signal can be recorded and/or reproduced is formed on a major surface of a disc substrate thereof; a light transmitting layer which can transmit a laser beam used in a process for recording and/or reproducing the information signal is formed on a side on which the information signal area is present; and a clamp reference plane is arranged on a major surface of the light transmitting layer in a clamp region.

Abstract: An optical disc comprising a recording layer upon which a groove and land are formed for recording a data signal upon both the groove and the land, and further wherein both of the groove and the land have substantially identical recording characteristics.

Abstract: 2-Sulfamoylbenzoic acid derivatives of general formula (I): 1

Abstract: 2-Sulfamoylbenzoic acid derivatives of general formula (I): which have both an antagonistic effect on the leukotriene D4 receptor and an antagonistic effect on the thromboxane A2 receptor and salts thereof, pharmaceuticals, anti-allergic agents and leukotriene-thromboxane A2 antagonistic agents containing them as an active ingredient.

Abstract: In the manufacturing process of recording media by transcribing information signals formed on a stamper onto the substrate, high-quality transcriptions must be achieved without causing any thermal deformations or warps. To this end, when the convexconcaves formed on a main surface of the stamper representing information signals are transcribed onto the substrate, a main surface of said substrate and a main surface of said stamper where the convexconcaves are formed are brought into contact facing each other, and said substrate and said stamper are pressurized with a prescribed pressure as they remain in contact, and in addition the temperature of only the contact surface layer of said substrate with said stamper is raised.

Abstract: The present invention provides an optical disc of the land/groove method having equivalent optical characteristics for the land and the groove, serving as an optimal optical disc for the land/groove recording.

Abstract: 2-Sulfamoylbenzoic acid derivatives of general formula (I): which have both an antagonistic effect on the leukotriene D4 receptor and an antagonistic effect on the thromboxane A2 receptor and salts thereof, pharmaceuticals, anti-allergic agents and leukotrienethromboxane A2 antagonistic agents containing them as an active ingredient.

Abstract: A thiophene derivative containing a phenylamidino group represented by the general formula (I): ##STR1## wherein R.sup.1 and R.sup.2 are the same or different from each other and are hydrogen atom, a halogen atom, an alkyl group having 1 to 4 carbon atoms or an alkoxyl group having 1 to 4 carbon atoms; or a pharmacologically acceptable salt thereof. The compound is useful for the treatment of inflammatory diseases.

Abstract: Quinolinecarboxylic acid derivatives which are represented by the general formula (I) ##STR1## wherein R.sub.1 is a C.sub.1 to C.sub.6 alkyl group which may be substituted, a C.sub.2 to C.sub.6 alkenyl group which may be substituted, a C.sub.3 to C.sub.7 cycloalkyl group which my be substituted or an aryl group which may be substituted,R.sub.2 is hydrogen atom; a halogen atom; hydroxyl group which may be protected, amino group or a C.sub.1 to C.sub.6 alkylamino group each of which may be protected; a C.sub.1 to C.sub.6 dialkylamino group or a C.sub.1 to C.sub.6 alkyl group,R.sub.3 is hydrogen atom or a C.sub.1 to C.sub.6 alkyl group,A is nitrogen atom or ##STR2## wherein A' is hydrogen atom. a halogen atom, a C.sub.1 to C.sub.6 alkyl group, a C.sub.1 to C.sub.6 alkoxyl group which may be substituted, cyano group, or nitro group, and A' may form a ring with R.sub.1 ; the ring may include oxygen atom, nitrogen atom, or sulfur atom as a constituent atom; the ring may be substituted with a C.sub.1 to C.sub.

Abstract: An oxime derivative of the formula: ##STR1## wherein R is a hydrogen atom or a C.sub.1-5 alkyl group, R.sub.1 is a hydrogen atom, a C.sub.1-5 alkyl group or a carboxyl-protecting group, R.sub.2 is a hydrogen atom, a halogen atom, a hydroxyl group or an amino group, R.sub.3 is a C.sub.3-7 cycloalkyl group, R.sub.4 is a hydrogen atom, a halogen atom or a C.sub.1-4 alkoxy group, each of R.sub.5 and R.sub.6 which may be the same or different, is a hydrogen atom or a C.sub.1-5 alkyl group, or R.sub.5 and R.sub.6 together represent a C.sub.2-4 alkylene group which forms together with the adjacent carbon atom a C.sub.3-5 ring, provided that when R.sub.2 is a hydrogen atom, R.sub.4 is a C.sub.1-4 alkoxy group, m is an integer of 0 or 1, and n is an integer of from 1 to 3; or its pharmaceutically acceptable salt.

Abstract: A 1,4-dihydropyridine derivative having the formula (I): ##STR1## wherein X is oxygen atom or nitrogen atom; when X is oxygen atom, R.sup.1 is hydrogen atom, a lower alkyl group, a lower cycloalkyl group, a lower alkenyl group or magnesium atom, when X is nitrogen atom, X-R.sup.1 group is NH.sub.2, NHR.sup.1', NR.sup.1' R.sup.1" or ##STR2## in which R.sup.1' is a lower alkyl group or a lower alkoxyalkyl group, R.sup.1" is a lower alkyl group and n is an integer of 2 to 6; R.sup.2 is a lower alkyl group, a lower cycloalkyl group or a lower alkoxyalkyl group and R.sup.3 is a lower alkyl group, formyl group, dimethoxymethyl group, cyano group or amino group, when X is oxygen atom and R.sup.1 is hydrogen atom or magnesium atom, R.sup.3 is methyl group, when X is nitrogen atom, R.sup.3 is methyl group, or a pharmaceutically acceptable salt thereof, some processes for preparing the same and a pharmaceutical composition containing the same.

Abstract: An electromagnetic actuator for a valve stem comprising a stator core having concentratedly wound coils around salient poles and the stator is positioned outside of a tubular member made of a nonmagnetic material. The electromagnetic actuator for a valve stem also has a rotor provided inside the tubular member for driving a threaded operating shaft such that it operats an objective member reciprocally an electromagnetic actuator for a valve stem is further constructed such that permanent magnets, alternately magnetized into a number of pole-pairs, are arranged along the surface of each salient pole of the stator core at a constant pitch, while a number of induction teeth are formed along the circumference of the rotor at a pitch equal to the pitch of the pole-pairs of the permanent magnets. The difference between the total number of the induction teeth and the total number of the polepairs of the permanent magnets is made equal to an even number.

Abstract: The present invention relates to the synthesis of dimer alkaloid compounds, particularly those of the Catharantus (Vinca) family, from an indole unit, such as cantharanthine, and a dihydroindole unit, such as vindoline. A multi-step process is disclosed including the steps of (1) of 1,4-reduction of a first dimeric iminium intermediate to an enamine compound by reaction with a 1,4-dihydropyridine compound; (2) oxidative transformation of the resulting enamine to a second iminium intermediate under controlled aeration; (3) reduction of the second iminium intermediate to form the target dimer alkaloid compounds. The entire process can be conducted in a one-pot operation to obtain the target compounds without isolation of the intermediates.

Abstract: A motor-operated valve is constructed such that a stator is provided outside of a nonmagnetic tubular member allowing flow of a fluid, with stator coils wound around a plurality of magnetic poles, and a plurality of permanent magnets are secured to an operating surface of each magnetic pole. The permanent magnets are magnetized into a number of pole-pairs arranged at a constant pitch. A rotor is rotatably supported inside of the tubular member. A number of induction teeth are formed along the circumference of the rotor at a pitch equal to the pitch of the pole-pairs of the permanent magnets, and the total number of the induction teeth is so selected that it is different from the total number of the pole-pairs of the permenant magnets by an amount equal to an even number. A mechanism including a rotation-preventing means is also provided in the rotor for converting the rotating movement of the rotor into a linear movement of a valve member.

Abstract: A method and apparatus are disclosed for improving step coverage of a wiring layer of a semiconductor device especially at the contact holes thereof. The inside of the contact holes are covered by a polysilicon layer deposited by chemical vapor deposition (CVD), and selectively doped with impurities having the same conductivity type as the contact region which the polysilicon layer contacts at the bottom of the contact hole. The remaining part of the contact hole is buried with SiO.sub.2, and the wiring layer is formed on it. Since the step coverage of the material deposited by CVD is very good, the disconnection at the side walls of the contact hole is avoided. Further, short circuits caused by growth of spikes of eutectic of silicon and aluminum is also avoided. If the surface of the polysilicon layer is covered with a thin film of SiO.sub.2 or Si.sub.3 N.sub.4, the material to bury the contact hole may be replaced by other materials such as polysilicon or amorphous silicon.

Abstract: A chromene derivative having the general formula (I): ##STR1## wherein n is 1 to 5 and --O--CH.sub.2).sub.n CO.sub.2 H group is attached to 5-position, 6-position, 7-position or 8-position, or salts thereof, a process for preparing the same and antiallergic agents containing the same.The compounds of the present invention inhibit the immunological release of chemical mediators such as SRS-A and histamine from mast cell and have an excellent effect in preventing and treating the various allergic diseases such as allergic asthma, allergic dermatitis, allergic nasitis, hives, allergic enteritis and allergic conjunctivitis, especially allergic asthma.

Abstract: A [2-hydroxy-3-(4-phenylpiperazinyl)propoxy]benzofuran derivative having the formula (I): ##STR1## wherein X is acetyl, carbamoyl, cyano, a lower alkoxycarbonyl, carboxyl or 1-hydroxyethyl group, R is hydrogen atom, a lower alkoxy group, a lower alkyl group or a halogen atom; R is attached to an arbitrary position of ortho-position, meta-position and para-position to N-phenyl group, and a group having the formula: ##STR2## is attached to an arbitrary position of 4, 5, 6 and 7 positions to benzofuran ring or the salt thereof, a process for preparing the same and an antihypertensive agent containing the same as an effective component. The benzofuran derivative has a strong .alpha.-adrenergic blockade effect and calcium antagonistic effect with a more decreased side-effect.

Abstract: [S]-(+)-2-acetyl-7-(2,3-epoxypropoxy)benzofuran (SEBF) is prepared by subjecting 2-acetyl-7-hydroxybenzofuran and [R]-glycidol to dehydration condensation in an inert organic solvent in the presence of triphenylphosphine and a dialkyl azodicarboxylate. The [S]-(+)-2-acetyl-7-(2,3-epoxypropoxy)benzofuran can be easily converted into [S]-2-acetyl-7-(2-hydroxy-3-isopropylaminopropoxy)benzofuran ([S]-befunolol) or salts thereof which are useful as a .beta.-adrenergic blocking agent, by reacting it with isopropylamine.

Abstract: Tetrazolylcoumarin derivatives of the general formula: ##STR1## wherein R is hydrogen atom, an alkyl group, an alkenyl group, an alkoxyalkyl group or phenyl group, n is an integer of 2 to 4, and the R--O--(CH.sub.2).sub.n --O-- group is substituted at any of the 5, 6, 7 and 8 positions of the coumarin ring, and the salts thereof. The compounds are useful as antiallergic agents for preventing and treating allergic diseases.

Abstract: The present invention relates to the synthesis of dimer alkaloid compounds, particularly those of the Catharantus (Vinca) family, from an indole unit, such as cantharanthine, and a dihydroindole unit, such as vindoline. A multi-step process is disclosed including the steps of (1) of 1,4-reduction of a first dimeric iminium intermediate to an enamine compound by reaction with a 1,4-dihydropyridine compound; (2) oxidative transformation of the resulting enamine to a second iminium intermediate under controlled aeration; (3) reduction of the second iminium intermediate to form the target dimer alkaloid compounds. The entire process can be conducted in a one-pot operation to obtain the target compounds without isolation of the intermediates.