Abstract: The present invention relates to compounds that are modulators of Integrin Linked Kinase (ILK), and methods of treating diseases with such compounds. In certain embodiments, the compounds are within Formulas I-VII (e.g., Csbl-1). In some embodiments, the compounds are used to treat an ILK-mediated disease, such as cancer (e.g., triple negative breast cancer) or an inflammatory disease.

Abstract: An electrochemiluminescence immunoassay system and a flow-through cell unit (1) thereof. The flow-through cell unit (1) comprises a working electrode (12), a counter electrode (11) and a reference electrode (13), wherein the working electrode (12) and the counter electrode (11) are vertically provided, and there is a liquid flow path between the two electrodes. When an electrochemical reaction occurs, and when reactants are evenly distributed on the working electrode (12) for a test. After the flow-through cell is cleaned, the liquid flow path is unblocked, so that the cleaning effect is better. A porous structure is provided on a connection surface where the reference electrode (13) is in communication with the liquid flow path, and the porous structure makes the reference electrode (13) have a good electrical conductivity, and prevents the reference electrode (13) from early ageing, and improves the durability of the flow-through cell unit (1).

Abstract: Embodiments of this application disclose a method for parsing a service platform address by a server. The server receives a DNS parsing request sent by a terminal, the DNS parsing request including a to-be-parsed domain name. The server then obtains target IP information of the terminal based on the DNS parsing request. When the target IP information has a corresponding target user-defined line, the server obtains a preset first parsing record based on the target user-defined line. The server then sends to the terminal a first IP address corresponding to the to-be-parsed domain name based on the preset first parsing record. As such, a corresponding IP address range can be defined using a user-defined line, so that a terminal within the IP address range can obtain a specific IP address corresponding to an access domain name, and provide a service to a user within a more accurate range.

Abstract: The application provides a cross-row time delay integral method, apparatus and camera. The method includes obtaining a first stage integral energy in an i-th target region from an i-th row of a first integral piece domain; transferring the first stage integral energy across rows to an i-th row of a second integral piece domain; obtaining the first stage integral energy and an second stage integral energy accumulated in the i-th target region from the i-th row of the second integral piece domain, after an integration period; outputting an image of the i-th target region containing the first stage integral energy and the second stage integral energy. The application performs cross-row integration through the energy obtained by imaging, the shooting of the target can be carried out in a higher-speed environment, the method can be implemented on the existing photoelectric device, and the method has excellent imaging quality and wide applicability.

Abstract: The present invention describes a method of treating a steroid-resistant disease or condition such as severe asthma in a subject by administering a therapeutically effective amount of an anthocyanin and a corticosteroid to a subject in need thereof.

Abstract: The present application relates to a detection method, belonging to the technical field of anti-fake detection. The detection method comprises steps of: acquiring reference imaging spectral data and imaging spectral data of a surface of an object to be detected; obtaining spectral reflectance of the surface of the object to be detected according to the reference imaging spectral data and the imaging spectral data of the surface of the object to be detected; matching the spectral reflectance of the object to be detected with spectral reflectance, stored in a calibration library, of an original object corresponding to the object to be detected; determining that the object to be detected is consistent with the original object if the matching of spectral reflectance is successful; and determining that the object to be detected is not consistent with the original object if the matching of spectral reflectance is failed.

Abstract: Embodiments of the present disclosure disclose a domain name resolution method, apparatus, and system, and a storage medium. The method includes: receiving a domain name resolution request sent by a network device, the domain name resolution request carrying a first target domain name that needs to be resolved; using the first target domain name as an initial value of a second target domain name; resolving the second target domain name, to obtain a corresponding resolution result; determining whether the resolution result is corresponds to a network address of a preset type; and repeating the aforementioned operations using the resolution result as the second target domain name until a resolution result corresponding to the network address of the preset type is obtained; and after obtaining the resolution result corresponding to the network address of the preset type, returning the resolution result to the network device.

Abstract: A service processing method, a device, a terminal and a server are provided. In some embodiments, the method includes: obtaining an operator identifier, when a coupon verification operation is detected on a service page of a public service account; invoking a code reading interface of an internet application to which the public service account belongs, to obtain a code of a coupon to be verified; generating a coupon verification service request based on the operator identifier and the code of the coupon; sending the coupon verification service request to a server, to cause the server to process a coupon verification service based on the operator identifier and the code of the coupon and return a process result to the terminal; and outputting the process result on the service page of the public service account.

Abstract: Embodiments of this application disclose a path data deletion method, a message forwarding method, and related apparatus. A controller disclosed in this application may obtain an identifier of an invalid path from a network node located on the invalid path, and determine, based on the identifier of the invalid path and a first network node providing the identifier of the invalid path, at least a second network node located on the invalid path. The controller is configured to send a path deletion message to the second network node to assist in cleaning invalid path data remaining in a network node, so that it is possible to disable periodic path data synchronization of a network node in a RSVP-TE mechanism. In addition, because path data of an invalid path is cleaned, abnormal data forwarding can be avoided and system stability can be improved.

Abstract: Disclosed are a communication method, a terminal and a communication system, which are applied between a terminal and a base station in a line of sight communication environment. A first polarizing antenna having the same polarity as that of a second polarizing antenna of a base station is set on a terminal, wherein the first polarizing antenna includes a first antenna component and a second antenna component having different polarities; and a first signal and a second signal which are sent by the base station via the second polarizing antenna are received via the first polarizing antenna.

Abstract: The present application relates to a detection method, belonging to the technical field of anti-fake detection. The detection method comprises steps of: acquiring reference imaging spectral data and imaging spectral data of a surface of an object to be detected; obtaining spectral reflectance of the surface of the object to be detected according to the reference imaging spectral data and the imaging spectral data of the surface of the object to be detected; matching the spectral reflectance of the object to be detected with spectral reflectance, stored in a calibration library, of an original object corresponding to the object to be detected; determining that the object to be detected is consistent with the original object if the matching of spectral reflectance is successful; and determining that the object to be detected is not consistent with the original object if the matching of spectral reflectance is failed.

Abstract: The present invention describes compounds according to formula I: and compounds according to formula II: and additional related flavonoid compounds, as well as the use of the compounds in methods for the prevention or treatment of IL-17A-mediated disease in a subject.

Abstract: A checking tool for measuring a distance between adjacent sinking grooves in an inner hole of a mechanical part, including: a gage block, end cover, sliding piece, pin, base, pin seat, support, measuring rod, spring, barrel, and dial indicator. An inner end face of the base is provided with the sliding piece, at least three concentric circular arc grooves are on the end face, paired eccentric arc grooves are on the sliding piece, the pin connected to the pin seat runs through the base and sliding piece, which is axially limited by the end cover, and the seat rotates relative to the base to realize radial expansion displacement of the sliding piece. A measuring head is formed by the dial indicator, measuring rod, spring and barrel. By positioning the edges of adjacent sinking grooves in an inner hole, measurement for a distance between the grooves is converted into depth measurement.

Abstract: Embodiments of the present disclosure disclose a domain name resolution method, apparatus, and system, and a storage medium. The method includes: receiving a domain name resolution request sent by a network device, the domain name resolution request carrying a first target domain name that needs to be resolved; using the first target domain name as an initial value of a second target domain name; resolving the second target domain name, to obtain a corresponding resolution result; determining whether the resolution result is corresponds to a network address of a preset type; and repeating the aforementioned operations using the resolution result as the second target domain name until a resolution result corresponding to the network address of the preset type is obtained; and after obtaining the resolution result corresponding to the network address of the preset type, returning the resolution result to the network device.

Abstract: Embodiments of this application disclose a method for parsing a service platform address by a server. The server receives a DNS parsing request sent by a terminal, the DNS parsing request including a to-be-parsed domain name. The server then obtains target IP information of the terminal based on the DNS parsing request. When the target IP information has a corresponding target user-defined line, the server obtains a preset first parsing record based on the target user-defined line. The server then sends to the terminal a first IP address corresponding to the to-be-parsed domain name based on the preset first parsing record. As such, a corresponding IP address range can be defined using a user-defined line, so that a terminal within the IP address range can obtain a specific IP address corresponding to an access domain name, and provide a service to a user within a more accurate range.

Abstract: An electrochemiluminescence immunoassay system and a flow-through cell unit (1) thereof. The flow-through cell unit (1) comprises a working electrode (12), a counter electrode (11) and a reference electrode (13), wherein the working electrode (12) and the counter electrode (11) are vertically provided, and there is a liquid flow path between the two electrodes. When an electrochemical reaction occurs, and when reactants are evenly distributed on the working electrode (12) for a test. After the flow-through cell is cleaned, the liquid flow path is unblocked, so that the cleaning effect is better. A porous structure is provided on a connection surface where the reference electrode (13) is in communication with the liquid flow path, and the porous structure makes the reference electrode (13) have a good electrical conductivity, and prevents the reference electrode (13) from early ageing, and improves the durability of the flow-through cell unit (1).

Abstract: Disclosed are a communication method, a terminal and a communication system, which are applied between a terminal and a base station in a line of sight communication environment. A first polarizing antenna having the same polarity as that of a second polarizing antenna of a base station is set on a terminal, wherein the first polarizing antenna includes a first antenna component and a second antenna component having different polarities; and a first signal and a second signal which are sent by the base station via the second polarizing antenna are received via the first polarizing antenna.

Abstract: An electrochemiluminescence immunoassay method is disclosed and uses a full reaction of a Ru(bpy) marked protein-primary antibody, a biotinylated protein-secondary antibody to be tested, and a sample to be tested; addition of a Streptavidin-coated magnetic particle to form a complex comprising an antigen, an antibody, and a magnetic particle; adsorption to an electrode surface by the magnetic particle; addition of a dibutyl ethanolamine solution; and testing by an electrochemical method. Also disclosed is a corresponding electrochemiluminescence immunoassay detection kit.

Abstract: A checking tool for measuring a distance between adjacent sinking grooves in an inner hole of a mechanical part, including: a gage block, end cover, sliding piece, pin, base, pin seat, support, measuring rod, spring, barrel, and dial indicator. An inner end face of the base is provided with the sliding piece, at least three concentric circular arc grooves are on the end face, paired eccentric arc grooves are on the sliding piece, the pin connected to the pin seat runs through the base and sliding piece, which is axially limited by the end cover, and the seat rotates relative to the base to realize radial expansion displacement of the sliding piece. A measuring head is formed by the dial indicator, measuring rod, spring and barrel. By positioning the edges of adjacent sinking grooves in an inner hole, measurement for a distance between the grooves is converted into depth measurement.

Abstract: A service processing method, a device, a terminal and a server are provided. In some embodiments, the method includes: obtaining an operator identifier, when a coupon verification operation is detected on a service page of a public service account; invoking a code reading interface of an internet application to which the public service account belongs, to obtain a code of a coupon to be verified; generating a coupon verification service request based on the operator identifier and the code of the coupon; sending the coupon verification service request to a server, to cause the server to process a coupon verification service based on the operator identifier and the code of the coupon and return a process result to the terminal; and outputting the process result on the service page of the public service account.