Patents by Inventor Jun Takakura

Jun Takakura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210071214
    Abstract: A method efficiently produces a compound containing an N-acyl-amino group by an enzymatic method. Specifically, a method of producing a compound containing an N-acyl-amino group includes producing the compound containing an N-acyl-amino group by reacting a compound containing an amino group with a compound containing a carboxyl group in the presence of an enzyme having an ability to bond a carboxyl group and an amino group in an ATP dependent manner to form an amide bond.
    Type: Application
    Filed: September 18, 2020
    Publication date: March 11, 2021
    Applicant: AJINOMOTO CO., INC.
    Inventors: Hidemi Nagata, Keiko Danjou, Jun Takakura, Hiroyuki Nozaki
  • Patent number: 10266857
    Abstract: The present invention provides a method for producing N?-dodecanoyl-L-lysine using an enzyme having properties suitable for the industrial production of N?-dodecanoyl-L-lysine. More specifically, the present invention provides a method for producing N?-acyl-L-lysine including reacting a carboxylic acid or a salt thereof and L-lysine or a salt thereof in the presence of a protein having an amino acid sequence of SEQ ID NO: 1; a protein having an amino acid sequence in which one or several amino acid residues are inserted, added, deleted, or substituted in the amino acid sequence of SEQ ID NO: 1 and having N?-acyl-L-lysine-specific aminoacylase activity; and a protein which has 90% or higher homology with the amino acid sequence of SEQ ID NO: 1 and having N?-acyl-L-lysine-specific aminoacylase activity.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: April 23, 2019
    Assignee: AJINOMOTO CO., INC.
    Inventors: Jun Takakura, Hiroyuki Nozaki
  • Publication number: 20180230502
    Abstract: The present invention provides a method for producing N?-dodecanoyl-L-lysine using an enzyme having properties suitable for the industrial production of N?-dodecanoyl-L-lysine. More specifically, the present invention provides a method for producing N?-acyl-L-lysine including reacting a carboxylic acid or a salt thereof and L-lysine or a salt thereof in the presence of a protein having an amino acid sequence of SEQ ID NO: 1; a protein having an amino acid sequence in which one or several amino acid residues are inserted, added, deleted, or substituted in the amino acid sequence of SEQ ID NO: 1 and having N?-acyl-L-lysine-specific aminoacylase activity; and a protein which has 90% or higher homology with the amino acid sequence of SEQ ID NO: 1 and having N?-acyl-L-lysine-specific aminoacylase activity.
    Type: Application
    Filed: April 17, 2018
    Publication date: August 16, 2018
    Applicant: AJINOMOTO CO., INC.
    Inventors: Jun Takakura, Hiroyuki Nozaki
  • Patent number: 9677106
    Abstract: A method for producing ?-Glu-Val-Gly comprising the step of reacting Val-Gly with a ?-glutamyl group donor in the presence of a ?-glutamyltransferase, a microorganism containing the enzyme, or a processed product thereof to generate ?-Glu-Val-Gly, wherein the ?-glutamyltransferase consists of a large subunit and a small subunit, and the small subunit has a specific mutation.
    Type: Grant
    Filed: August 12, 2016
    Date of Patent: June 13, 2017
    Assignee: Ajinomoto Co., Inc.
    Inventors: Hiroyuki Nozaki, Isao Abe, Jun Takakura, Rie Takeshita, Hideyuki Suzuki, Shunichi Suzuki
  • Patent number: 9580696
    Abstract: A method for producing ?-Glu-Val-Gly comprising the step of reacting Val-Gly with a ?-glutamyl group donor in the presence of a ?-glutamyltransferase, a microorganism containing the enzyme, or a processed product thereof to generate ?-Glu-Val-Gly, wherein the ?-glutamyltransferase consists of a large subunit and a small subunit, and the small subunit has a specific mutation.
    Type: Grant
    Filed: April 2, 2014
    Date of Patent: February 28, 2017
    Assignee: Ajinomoto Co., Inc.
    Inventors: Hiroyuki Nozaki, Isao Abe, Jun Takakura, Rie Takeshita, Hideyuki Suzuki, Shunichi Suzuki
  • Publication number: 20160355861
    Abstract: A method for producing ?-Glu-Val-Gly comprising the step of reacting Val-Gly with a ?-glutamyl group donor in the presence of a ?-glutamyltransferase, a microorganism containing the enzyme, or a processed product thereof to generate ?-Glu-Val-Gly, wherein the ?-glutamyltransferase consists of a large subunit and a small subunit, and the small subunit has a specific mutation.
    Type: Application
    Filed: August 12, 2016
    Publication date: December 8, 2016
    Applicant: Ajinomoto Co., Inc.
    Inventors: Hiroyuki NOZAKI, Isao Abe, Jun Takakura, Rie Takeshita, Hideyuki Suzuki, Shunichi Suzuki
  • Publication number: 20140212920
    Abstract: A method for producing ?-Glu-Val-Gly comprising the step of reacting Val-Gly with a ?-glutamyl group donor in the presence of a ?-glutamyltransferase, a microorganism containing the enzyme, or a processed product thereof to generate ?-Glu-Val-Gly, wherein the ?-glutamyltransferase consists of a large subunit and a small subunit, and the small subunit has a specific mutation.
    Type: Application
    Filed: April 2, 2014
    Publication date: July 31, 2014
    Applicant: Ajinomoto Co., Inc.
    Inventors: Hiroyuki NOZAKI, Isao Abe, Jun Takakura, Rie Takeshita, Hideyuki Suzuki, Shunichi Suzuki