Abstract: A mattress 100 includes a movable part 1 and a mattress body 2 including a first mattress part 21 disposed above the movable part 1, and a second mattress part 22 provided separately from the first mattress part 21 and disposed to surround the first mattress part in a plan view. The first mattress part 21 is configured to rotate upward about the predetermined rotation axis by the movable part 1.

Abstract: The present invention provides compounds of Formula (I), and pharmaceutically compositions thereof. Compounds of Formula (I) are binders of bromodomains and/or bromodomain-containing proteins (e.g., bromo and extra terminal (BET) proteins). Also provided are methods, uses, and kits using the compounds and pharmaceutical compositions for inhibiting the activity (e.g., increased activity) of bromodomains and/or bromodomain-containing proteins and for treating and/or preventing in a subject diseases associated with bromodomains or bromodomain-containing proteins (e.g., proliferative diseases, cardiovascular diseases, viral infections, fibrotic diseases, metabolic diseases, endocrine diseases, and radiation poisoning). The compounds, pharmaceutical compositions, and kits are also useful for male contraception.

Abstract: A manufacturing method, a manufacturing apparatus, a computer readable recording medium, and a program for manufacturing a machine component having a rotation symmetry plane are provided.

Abstract: A hardfacing alloy satisfies the following condition when the hardfacing alloy as a whole is 100 mass % (also simply referred to as “%,” hereinafter), Ni: 10-25%, Si: 1-3%, Fe: 3-18%, the total of one or more elements of Mo, W, and Nb: 6.5-20%, and the balance: Cu and impurities. In particular, it preferably satisfies Fe+2Mo?22.6(%), Mo equivalent/Fe?1.17, and Mo equivalent=Mo+0.522W+1.033Nb. In a hardfacing part composed of the hardfacing alloy, coarse hard particles are formed to ensure the wear resistance, and a soft phase present in the hard particles ensures the machinability. This may be understood as a raw material powder for hardfacing treatment and may also be understood as a hardfacing member in which a hardfacing part is formed on a base material using the raw material powder.

Abstract: A control unit that controls a transport apparatus executes selection control to select one accommodation portion as a selected accommodation portion, movement control to control the transport apparatus so as to move a transport support portion to a corresponding position, determination control to determine whether or not a detection target portion is detected by a detecting portion, transfer control to control the transport apparatus so as to transfer an article from the transport support portion to an accommodation support member, and update setting control to set the selected accommodation portion and related accommodation portions as prohibited accommodation portions if it is determined, in the determination control, that the detection target portion is not detected, and after the update setting control, the control unit again executes the selection control to newly select a selected accommodation portion, and executes the movement control so as to move the transport support portion to a corresponding pos

Abstract: The present invention relates to a manufacturing method for a bent plate with a printed layer including: holding the bent plate by bringing a second main surface of the bent plate into contact with a surface of a fixing jig in which the surface of the fixing jig has a shape corresponding to the second main surface; disposing a screen having a printing pattern portion above the bent plate; bringing a squeegee into contact with a printing start part of the bent plate via the screen; and causing the squeegee to relatively traverse the bent plate along the first main surface via the screen, in which an angle on a moving direction side of the squeegee is changed when the squeegee is caused to relatively traverse the bent plate.

Abstract: A method for manufacturing a machine component includes determining a track of a cutting edge and feeding the cutting edge along the track. The determining a track includes calculating a coordinate (X(t), Y(t), Z(t)) of a first end portion of the cutting edge in accordance with X(t)=(Rsh(t)cos ?(t)?Xchip(t)), Y(t)=(Rsh(t)sin ?(t)?Ychip(t)), and Z(t)=(Zsh(t)?Zchip(t)), where a variable t assumes (N+1) values not smaller than 0 and not greater than 1. ?(t) represents an angle formed by a straight line connecting a point of cutting projected on an XY plane and an origin of the XY plane to each other with respect to an X axis, and ?(t) satisfies a condition tan ? ? ? ? ( t ) = tan ? ? ? · tan ? ? ? s - tan ? ? ? · tan 2 ? ? + tan 2 ? ? - tan 2 ? ? s tan ? ? ? · tan ? ? ? s + tan ? ? ? · tan 2 ? ? + tan 2 ? ? - tan 2 ? ? s .

Abstract: A tool selection unit has an analysis unit and a selection unit. The analysis unit determines a pick feed direction and the feed direction of a tool on the basis of information relating to the shape of a machining region including a double curved surface or a machining surface in the machining region, and creates parameter information in which at least a value relating to the smallest curvature radius in the machining surface and a value relating to the largest curvature radius in the pick feed direction are recorded. The selection unit selects a tool to use for machining the machining region on the basis of the parameter information, from among a plurality of tools having a bottom cutting edge and a side cutting edge formed in a curved-surface shape having a curvature radius different from a curvature radius of a curved surface of the bottom cutting edge.

Abstract: The present invention provides bivalent inhibitors of BET bromodomains, such as compounds of Formulae (I), (II), (III), (IV), (V), and (VI). Some bromdomain-containing proteins (e.g., BRD4) have a tandem bromodomain primary structure comprising more than one bromodomain binding site (e.g., BRD4 comprises BD1 and BD2). Bivalent inhibitors of BET bromodomains provided herein can target bromodomains through advantageous multivalent interactions, and can therefore can be to treat diseases or conditions associated with bromodomain-containing proteins. The present also provides pharmaceutical compositions and kits comprising the inventive compounds, as well as methods of using the inventive compounds.

Abstract: A method of correcting a track of a cutting edge is provided. With movement of the cutting edge, a point on the cutting edge in contact with the rotation symmetry plane is moved along the cutting edge from a first end portion of the cutting edge to a second end portion of the cutting edge opposite to the first end portion. The correction method includes measuring, by a measurement unit, a shape of the cut and machined rotation symmetry plane, calculating, by an operation unit, an error of the measured shape of the rotation symmetry plane from a target shape of the rotation symmetry plane in a direction of the axial line of rotation, and correcting, by the operation unit, a component in the direction of the axial line of rotation of a track of a point of cutting based on the error.

Abstract: A display device includes a light transmitting substrate in which pixels are arranged, the pixels having a light transmitting region that transmits external light and a light emitting region in which a light emitting element is disposed; a first light blocking layer that is disposed in the light emitting region and blocks the external light; a thin film transistor that is disposed on the first light blocking layer and controls a light emission of the light emitting element; a first insulating layer that covers an active layer of the thin film transistor; a second light blocking layer that is disposed on the first insulating layer so as to cover the thin film transistor and blocks the external light; and a first light blocking wall that is connected to the first light blocking layer and the second light blocking layer and blocks the external light.

Abstract: The rectifying device converts high-frequency power input from an input terminal into direct current power and outputs the direct current power from an output terminal. The rectifying device includes a rectifier that converts the high-frequency power into the direct current power, and an impedance changer having one end connected to a connection point of the rectifier and the output terminal and the other end to which reference voltage is applied such that impedance varies while having a negative correlation with respect to an absolute value of voltage of the direct current power. When the absolute value of the voltage of the direct current power is greater than a predetermined value that is lower than reverse withstand voltage of the rectifying element included in the rectifier, the impedance of the impedance changer as viewed from the rectifier is a value regarded as corresponding to a short circuit.

Abstract: There are provided a virtual file generating unit 1 for designating an optional page of an optional electronic document to generate a virtual file, an object generating unit 4 for generating an object for visualizing the virtual file, and a virtual file access unit 6 for giving access to a designated page of an electronic document designated by the virtual file selected via the object. By only execution of a simple operation for designating a specific page in the electronic document to give an instruction for generating the virtual file, the virtual file and the object are generated. By only selection of a desirable object, access to a desirable page of a desirable electronic document is automatically given without performing a work for opening a file of an original electronic document to search for a specific page.

Abstract: A thin-film transistor substrate includes an insulating substrate, a first insulating layer, a first thin-film transistor including a first oxide semiconductor film, a second insulating layer located upper than the first insulating layer, and a second thin-film transistor including a second oxide semiconductor film different in composition from the first oxide semiconductor film. At least a part of the first oxide semiconductor film is provided above and in contact with the first insulating layer. The first insulating layer is the uppermost insulating layer among insulating layers located lower than and in contact with the first oxide semiconductor film. At least a part of the second oxide semiconductor film is provided above and in contact with the second insulating layer. The second insulating layer is the uppermost insulating layer among insulating layers located lower than and in contact with the second oxide semiconductor film.

Abstract: In at least some implementations, a method of controlling spark events in an engine includes determining for at least two engine revolutions in a four-stroke engine at least one characteristic of the primary coil voltage for a spark event, determining, based upon the characteristic of the primary coil voltage, which of the spark events is associated with a compression phase and which of the spark events is associated with an exhaust phase of engine operation, and providing spark events in subsequent engine revolutions that are associated with the compression phase of engine operation but not in revolutions associated with the exhaust phase of engine operation. In at least some implementations, the characteristic is the duration of the spark event as determined by changes in the primary coil voltage, and the characteristic may be that the duration that the primary coil voltage is above a threshold voltage.

Abstract: The present invention provides compounds of Formula (I), and pharmaceutically compositions thereof. Compounds of Formula (I) are binders of bromodomains and/or bromodomain-containing proteins (e.g., bromo and extra terminal (BET) proteins). Also provided are methods, uses, and kits using the compounds and pharmaceutical compositions for inhibiting the activity (e.g., increased activity) of bromodomains and/or bromodomain containing proteins and for treating and/or preventing in a subject diseases associated with bromodomains or bromodomain-containing proteins (e.g., proliferative diseases, cardiovascular diseases, viral infections, fibrotic diseases, metabolic diseases, endocrine diseases, and radiation poisoning). The compounds, pharmaceutical compositions, and kits are also useful for male contraception.

Abstract: A carbon fiber bundle that satisfies retaining a twist count of 2 turns/m or more when suspended with one end fixed and the other end free; having a single fiber diameter of 6.1 ?m or more and a heat loss rate at 450° C. of 0.15% or less, and formula (1) wherein Lc is crystallite size and ?002 is an orientation parameter of crystallites determined from bulk measurement of the entire fiber bundle: ?002>4.0×Lc+73.2 (1); and a carbon fiber bundle that satisfies: retaining a surface layer twist angle of 0.2° or more when suspended with one end fixed and the other end free; having a single fiber diameter of 6.1 ?m or more and a heat loss rate at 450° C. of 0.15% or less, and formula (1).

Abstract: A thin-film device includes a polysilicon element and an oxide semiconductor element. The polysilicon element includes a first part made of low-resistive polysilicon. The oxide semiconductor element includes a second part made of low-resistive oxide semiconductor. The first part and the second part are disposed to overlap each other and connected.

Abstract: An image forming apparatus using a contact charging method includes a control unit capable of executing cleaning in a post-rotation step at the end of a job and in an inter-image step during execution of the job. The cleaning involves moving toner adhering to a charging member from the charging member to an image bearing member. The job is a series of operations started by a predetermined start instruction and involving forming an image on one or more recording materials and outputting the one or more recording materials. When an instruction to start the next job is input during execution of cleaning in the post-rotation step, the control unit stops the cleaning in the middle of the execution, starts the next job, and adjusts timing for executing subsequent cleaning on the basis of information relating to the amount of cleaning executed before being stopped in the middle of the execution.