Abstract: Provided herein are compounds useful in the treatment of inflammatory diseases, pharmaceutical compositions comprising the same, and methods of use and preparation thereof. The compounds exhibit inhibitory effects on the expression and secretion of pro-inflammatory cytokines, such as IL-1?, IL-6 and TNF-?.

Abstract: The present invention provides a lighting system comprising a main power source, a light source driver electrically coupled to the main power source, and a light source unit driven by the light source driver. The light source driver is encased within a dedicated or independent driver housing. The light source driver and the driver housing are physically and electrically connected to the light source unit via a flexible cord. The length of the flexible cord is so configured that the light source unit can be installed at different locations inside a building without moving the light source driver around.

Abstract: A construction building equipment includes hanging pedestals, sleeve frames, hydraulic cylinders, upper reversing boxes, lower reversing boxes and track columns. The multiple hanging pedestals are fixed on an outer side of a shear wall of an external wall. The sleeve frames and the track columns are clamped on the hanging pedestals. The sleeve frames are clamped on outer sides of the track columns. The lower reversing boxes are fixed at upper ends of the sleeve frames. The hydraulic cylinders are connected with the upper reversing boxes and the lower reversing boxes. Side surfaces of the track columns are provided with pane holes for cooperative climbing of the upper reversing boxes and the lower reversing boxes. Upper ends of the track columns are fixedly connected with a top platform. Hangers and formworks are suspended on the top platform through booms.

Abstract: The present invention discloses a soft soil foundation single-hole depth air compression drainage device and working method thereof, comprising an air compression pipe and a water drainage pipe. A water drainage cavity body and an air diffusion cavity body are buried respectively in a soft soil foundation, and the air diffusion cavity body is located below the water drainage cavity body. Connecting to the air diffusion cavity body, the air compression pipe protrudes out of ground surface along a vertical direction of the soft soil foundation and communicates with an inflation pump; connecting to the water drainage cavity body, one end of the water drainage pipe protrudes to the bottom of the water drainage cavity body, and the other end protrudes out of the ground surface, thus achieving deep drainage and a drainage consolidation time of the deep soft soil foundation is shortened.

Abstract: A three-level boost converter and a control method. The three level flying-capacitor boost converter includes: an inductor, a flying capacitor, a controller, a first switching transistor and a second switching transistor as primary power transistors. When a voltage of the flying capacitor is less than or equal to a half of a bus voltage, a first driving signal is sent to the first switching transistor, and a second driving signal is sent to the second switching transistor; or when a voltage of the flying capacitor is greater than a half of a bus voltage, a first driving signal is sent to the second switching transistor, and a second driving signal is sent to the first switching transistor. The bus voltage is an output voltage Vo of the three-level boost converter.

Abstract: A resource determining method receiving, by a transmission user equipment , scheduling request (SR) configuration information from a network device, where the SR configuration information corresponds to a sidelink (SL) signaling radio bearer (SRB), where the SR configuration information indicates a first SR resource, and the transmission user equipment is a device on an sidelink SL. The transmission user equipment sends an SR to the network device using the first SR resource.

Abstract: A computer-implemented method includes obtaining a plurality of textual records divided into clusters and a residual set of the textual records, where a machine learning (ML) clustering model has divided the plurality of textual records into the clusters based on a similarity metric. The method also includes receiving, from a client device, a particular textual record representing a query and determining, by way of the ML clustering model and based on the similarity metric, that the particular textual record does not fit into any of the clusters. The method additionally includes, in response to determining that the particular textual record does not fit into any of the clusters, adding the particular textual record to the residual set of the textual records. The method can additionally include identifying, by way of the ML clustering model, that the residual set of the textual records contains a further cluster.

Abstract: The present invention discloses a soft soil foundation porous-depth air compression drainage device and working method thereof, comprising an air compression pipe and a water drainage pipe. A water drainage cavity body and an air diffusion cavity body are buried respectively in a soft soil foundation; the drainage cavity bodies are disposed around the air diffusion cavity body. Connecting to the air diffusion cavity body, the air compression pipe protrudes out of ground surface along a vertical direction of the soft soil foundation and communicates with an inflation pump; connecting to the water drainage cavity body, one end of the water drainage pipe protrudes to the bottom of the water drainage cavity body, and the other end protrudes out of the ground surface along the vertical direction of the soft soil foundation, thus achieving deep drainage and a drainage consolidation time of the deep soft soil foundation is shortened.

Abstract: Embodiments of this application provide a communication path switching method, an apparatus, and a system. The method includes: A first terminal receives a first radio resource control (RRC) connection reconfiguration message sent by a first network device, the first RRC connection reconfiguration message comprises a first identifier, a second identifier, and first indication information, the first identifier identifies the first terminal, the first indication information indicates the first terminal to perform communication path switching, the second identifier identifies a second terminal, and the second terminal is a target terminal for the communication path switching; and the first terminal sends a first message to the second terminal, the first message comprises the first identifier.

Abstract: An array substrate, a display device and a fabrication method are provided. The array substrate includes a first metal layer at one side of a base substrate, the first metal layer including a light shielding part, a source, a drain in a display area; a second metal layer at a side, facing away from an active layer, of gate insulating layer, the second metal layer includes a gate, a source-landing electrode a drain-landing electrode in the display area, the source-landing electrode is in contact with the active layer and the source through a first via hole penetrating through the gate insulating layer and a buffer layer and exposing one end of the active layer, the drain-landing electrode is in contact with the active layer and the drain through a second via hole penetrating through the gate insulating layer and the buffer layer and exposing other end of the active layer.

Abstract: A cyclic thioether compound has a structure represented by the following formula (I). A vegetable oil composition contains the cyclic thioether compound. When the cyclic thioether compound is used as a drilling fluid lubricant in a drilling fluid. The lubrication performance of the drilling fluid can be significantly improved.

Abstract: Methods and an apparatus for removing particles or photoresist on substrates. In an embodiment, a method comprises the following steps: transferring one or more substrates into a DIO3 solution accommodated in a DIO3 bath; after the one or more substrates are processed in the DIO3 bath, taking the one or more substrates out from the DIO3 bath and transferring the one or more substrates into a SPM solution accommodated in a SPM bath; after the one or more substrates are processed in the SPM bath, taking the one or more substrates out from the SPM bath and rinsing the one or more substrates; and transferring the one or more substrates to one or more single chambers to perform single substrate cleaning and drying process. The method combines DIO3 and SPM in one cleaning sequence, which can remove particles or photoresist, especially remove photoresist treated by medium dose or high dose of ion implantation.

Abstract: The invention discloses a modified chitosan-LZM-CA composite antibacterial cling film optimized by response surface methodology and the preparation method and application thereof, relates to the technical field of food packaging materials. The invention provides freshwater crayfish as the research object, and adopts the modified chitosan, lysozyme (LZM), a good film-forming material carrageenan (CA) as the composite antibacterial cling film materials, and through the response surface experimental design to determine the best ratio of modified chitosan-LZM-CA composite antibacterial cling film. Furthermore, the TVB-N value and the change value of the total number of bacterial colonies of the freshwater crayfish with the composite antibacterial cling film during refrigeration, can be regarded as indicators to examine the preservation effect, providing a theoretical basis of the chitosan composite film preservation technology development and application for freshwater crayfish and other aquatic products.

Abstract: This invention is in the field of medicinal pharmacology. In particular, the present invention relates to pharmaceutical agents which function as inhibitors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral replication and/or SARS-CoV-2 related viral 3CL protease (Mpro) activity. The invention further relates to methods of treating and/or ameliorating symptoms related to conditions caused by the SARS-CoV-2 virus (e.g., COVID-19), comprising administering to a subject (e.g., a human patient) a composition comprising one or more pharmaceutical agents which function as inhibitors of SARS-CoV-2 viral replication and/or inhibitors of SARS-CoV-2 related Mpro activity.

Abstract: According to an embodiment, a source object presented in a source video is identified. Attribute information of the source object in respective frames of a sequence of source frames in the source video is identified. The attribute information represents an animation effect associated with the source object across the sequence of source frames. The attribute information is provided for use in reproducing the animation effect in a target video.

Abstract: The present invention discloses a fault diagnosis method under a convergence trend of a center frequency, including: (1) acquiring a dynamic signal x(t) of a rotary machine equipment; (2) setting initial decomposition parameters of a variational model; (3) decomposing the dynamic signal x(t) by using the variational model with the set initial decomposition parameters, and traversing a signal analysis band and performing iterative decomposition on the dynamic signal x(t) under the guidance of a convergence trend of a center frequency, to obtain optimized modals {m1 . . . mn . . . mN} and corresponding center frequencies {?1 . . . ?n . . . ?N}; (4) searching a fault related modal mI, guiding parameter optimization by using a center frequency ?I of the fault related modal mI, and retrieving an optimal target component mI including fault information; and (5) performing envelopment analysis on the optimal target component mI, and diagnosing the rotary machine equipment according to an envelope spectrum.

Abstract: The invention provides an adaptive manifold probability distribution-based bearing fault diagnosis method, including constructing transferable domains and transfer tasks; converting a data sample in each transfer task into frequency domain data via Fourier transform, inputting the frequency domain data into a GFK algorithm model, and calculating a manifold feature representation matrix related to a bearing fault in each transfer task by using the GFK algorithm model; calculating a cosine distance between centers of a target domain and a source domain in each transfer task according to a manifold feature representation, and defining a target function of in-domain classifier learning; then solving the target function, to obtain a probability distribution matrix of the target domain; and selecting a label corresponding to the largest probability value corresponding to each data sample in the target domain from the probability distribution matrix as a predicted label of the data sample in the target domain.