Abstract: Use of a TGF-? small molecule inhibitor in the field of nerve regeneration, for in vitro regeneration and directed differentiation of a variety of nerve cells and brain-like organs. By adding the TGF-? small molecule inhibitor to a set of basal media having clear chemical compositions, pluripotent stem cells can be induced into adult cells derived from a variety of neural stem cells, and the number of induced nerve cells can be greatly increased.

Abstract: Disclosed are systems, apparatuses, processes, and computer-readable media to capture audio. A method of processing audio data includes obtaining first audio information from a user using an audio sensor of a user device; determining whether the first audio information includes audio corresponding to a detected keyword that configures the user device to receive or process one or more commands from the user; based on the first audio information including the audio corresponding to the detected keyword, determining a similarity between the first audio information corresponding to the detected keyword and a model of an authenticated user; and determining whether to authenticate the user as the authenticated user based on a comparison of the similarity between the first audio information and the model of the authenticated user to a first threshold.

Abstract: Disclosed is a fluid parameter measurement device with an annular gap, including a base, a core column, and a swing block. The base is fixed to the core column and pivot-connected to the swing block. The core column penetrates a through hole in the swing block, sealed at both ends with elastic sealing rings to form an annular gap between a wall of the core column and that of the through hole. The core column contains fluid inlet and outlet channels connecting both ends of the annular gap, directing pressurized liquid through the annular gap. An adjustment assembly on the base alters core column-to-through hole concentricity while maintaining parallelism, enabling flow measurement under varying pressures or at constant pressure with adjustable eccentricity. The design simplifies experimental operations through precise concentricity regulation and eccentricity-based gap state control.

Abstract: Disclosed is a fluid parameter measurement device with an annular gap, including a base, a core column, and a swing block. The base is fixed to the core column and pivot-connected to the swing block. The core column penetrates a through hole in the swing block, sealed at both ends with elastic sealing rings to form an annular gap between a wall of the core column and that of the through hole. The core column contains fluid inlet and outlet channels connecting both ends of the annular gap, directing pressurized liquid through the annular gap. An adjustment assembly on the base alters core column-to-through hole concentricity while maintaining parallelism, enabling flow measurement under varying pressures or at constant pressure with adjustable eccentricity. The design simplifies experimental operations through precise concentricity regulation and eccentricity-based gap state control.

Abstract: Provided is a new use of a TGF-? small molecule inhibitor in the field of neuroregeneration, which can be used for the in vitro regeneration and directed differentiation of various nerve cells and brain-like organs. By adding same to a set of basal media having clear chemical compositions. pluripotent stem cells can be induced into adult cells derived from a variety of neural stem cells, and the number of induced nerve cells and the size of organoids can be greatly increased. The induction system provided in the present invention expands new functions of a single small molecule in the field of ectodermal cell induction and differentiation and at the same time avoids the use of B27 and other serum substitutes, thereby completely avoiding the potential risks caused by the presence of animal-derived components in cell culture processes, and greatly expanding the clinical prospects of a variety of nerve cell transplantations.

Abstract: A support device includes a support structure and a carrier assembly. The support structure includes a connection groove. The carrier assembly is configured to support a host system and/or a display device and includes a first connector. At least a part of the first connector is located in the connection groove and sliding in the connection groove. An angle between the host system and/or the display device and the support structure is adjusted in a first direction and/or a second direction by sliding the first connector in the connection groove.

Abstract: A driving control apparatus, a driving control method and a display apparatus. When a display panel is in a power-on state and it is determined that a user leaves the display panel, a backlight stop signal (VBN) is first output, and a voltage stop signal (VPN) is then output. A backlight control circuit (320) stops operating in response to the backlight stop signal. In response to the voltage stop signal, a power switching circuit (330) stops outputting a driving voltage for driving the display panel to display a picture. When determining that the user returns to the front of the display panel, a voltage start signal (VPQ) can first be output, and a backlight start signal (VBQ) is then output. The backlight control circuit starts to operate in response to the backlight start signal. The power switching circuit outputs the driving voltage in response to the voltage start signal.

Abstract: A high-selectivity activator capable of being used for OCT4 and downstream gene expression, a pharmaceutical composition thereof, and a preparation method therefor. The activator has the following formula: wherein, A1, m1, m2, A2 and A3 are described in this paper.

Abstract: Embodiments provide a semiconductor structure and a method for fabricating the same. The method includes: providing a substrate; forming, in the substrate, active pillars spaced and isolation layers configured to isolate the active pillars; forming, in an active pillars and an isolation layers, word line trenches extending along a first direction; and forming a first word line in the first word line trench and a second word line in the second word line trench, where opposite surfaces of the first word line form a first gate channel together with the active pillar, opposite surfaces of the second word line form a second gate channel together with the active pillar, and sum of a width of the first gate channel along the first direction and a width of the second gate channel along the first direction is greater than a perimeter of the active pillar.

Abstract: Provided by the present disclosure are an amino quinazolinone and amino isoquinolone derivatives. It is verified by numerous experiments that the compounds provided by the present disclosure have good inhibiting effects on PI3K? and PI3K?, most of the compounds have prominent inhibiting effect on PI3K?, and show strong growth inhibiting effect on PIK3CA mutant tumor cells such as human breast cancer cell strain (MCF7). Therefore, the amino quinazolinone and amino isoquinolone derivatives according to the present disclosure can be applied in the preparation of anti-tumor and anti-inflammatory medicines, and can be used as PI3K? inhibitors in the preparation of medicines for treatment of human or animal cell proliferation related tumors, the medicines comprising the derivatives any one or more of pharmaceutically acceptable salts and solvates thereof as well as pharmaceutically acceptable carriers.

Abstract: The present disclosure relates to methods and apparatus for image processing. An example method includes receiving, from an application, a request to access an image, wherein the application is enabled access to one or more categories of image content, processing the image to modify one or more portions of the image that include content not within the one or more categories, and providing, to the application, the processed image.

Abstract: The present invention discloses the use of marker genes in detecting residual pluripotent stem cells, detection methods, and reagent kits, wherein the marker genes include at least one of TDGF1 and TRIML2, which are genes specifically highly expressed in human pluripotent stem cells. The selection of these marker genes is based on high-throughput RNA sequencing technology, which identifies genes that are significantly upregulated specifically in pluripotent stem cells compared to pluripotent stem cell-derived cell samples. A set of candidate genes suitable for identifying residual pluripotent stem cells is then selected and validated. The marker genes provided by the invention can be used to detect and identify residual pluripotent stem cells in pluripotent stem cell-derived cell products for clinical treatment, thus serving as a quality control measure for clinical cell products.

Abstract: The present disclosure discloses an oscillating-pressure-and-spark-plasma combined sintering equipment and sintering method. By providing a system comprising a mainframe structural system, a servo motor hydraulic system, an oscillating pressurized hydraulic system, a vacuum and inert gas supply system, a pulse plasma power control system, and a mainframe control system, the mainframe structure adopts a pre-tightened frame beam to ensure the strength of the system under oscillation pressure and the stability of the overall structure. The equipment is additionally provided with an oscillation hydraulic system with adjustable frequency and pressure. During the sintering process of workpieces, the oscillation pressure can achieve the slip rearrangement of particles. It adopts an overlay mode of dual hydraulic systems. Therefore, the accuracy of pressure control in the system is ensured.

Abstract: Techniques described herein are directed to improving a user keyword detection model using user audio samples that have been falsely rejected. In some embodiments, user equipment (UE) may detect multiple attempts by a user at uttering a keyword. A true keyword that matches keyword models implemented by the UE may activate a desired function, such as initiating an assistant application, initiating a specific application, waking up from a lower power state, transitioning to a lower power state, toggling a power-saving mode, unlocking or locking the device, etc. Any true keywords uttered prior to detection of the true keyword but which have been falsely rejected may be sent to a server to train the keyword model and generate an updated keyword model. The updated keyword model may be received by the UE to replace the keyword model being used, allowing the UE to continually improve keyword detection accuracy.

Abstract: A power supply circuit, a driving method thereof, a printed circuit board, a display module and a display apparatus are disclosed, which relates to a technical field of displaying. The power supply circuit includes a first power management chip and a second power management chip configured to be respectively connected with a display panel and provide different driving signals to the display panel, and the driving signals are configured for driving the display panel to display.

Abstract: The disclosed semiconductor structure includes a conductive layer, a channel in the conductive layer. The inner wall of the channel is covered with a first dielectric layer. The thickness of the first dielectric layer is greater at the orifice of the channel than the thickness on the side away from the orifice; the first dielectric layer on the side close the orifice is covered with a second dielectric layer, and the second dielectric layer blocks the orifice; an air gap is formed in the first dielectric layer and the second dielectric layer, and the size of the air gap on the side away from the orifice is larger than the size of the air gap on the side close to the orifice. The present application can effectively reduce the parasitic capacitance of the conductive connection structure, alleviate its RC delay problem, and optimize the storage performance of the memory.

Abstract: Provided are a semiconductor structure and a method for manufacturing same. The semiconductor structure includes a target structure, a low dielectric constant material layer disposed on the target structure, and a protective layer disposed on the low dielectric constant material layer. The low dielectric constant material layer and the protective layer are prepared from the same precursor, and the protective layer has a lower carbon content.