Abstract: Electroporation cartridges for single use electroporation as well as electroporation cartridges for automated batch processing, electroporation instruments and systems and methods of electroporation using these devices and systems. Electroporation cartridges include an electroporation chamber defined by an elongate body, a first electrode at a proximal end and a second electrode at a distal end of a chamber. Electroporation systems include one or more components including a pulse generator, compartments for placing either flow-through or single use electroporation cartridges, components for storage of cells, cooling and pre-cooling mechanisms, removably insertable modular casings having compartments for holding and arranging electroporation system and reagent components, one or more pumps for moving sample through the system, and processors and controllers.

Abstract: The present disclosure provides electroporation cartridges for single use electroporation as well as electroporation cartridges for automated batch processing, electroporation instruments and systems and methods of electroporation using these devices and systems. In some embodiments, electroporation cartridges comprise an electroporation chamber defined by an elongate body, a first electrode at a proximal end and a second electrode at a distal end of a chamber. Electroporation systems of the disclosure include one or more components including a pulse generator, compartments for placing either flow-through or single use electroporation cartridges, components for storage of cells, cooling and pre-cooling mechanisms, removably insertable modular casings having compartments for holding and arranging electroporation system and reagent components, one or more pumps for moving sample through the system, and processors and controllers.

Abstract: A sheet gripping mechanism includes a first sheet guide including a guide surface facing a sheet conveyance path along which a sheet is to be conveyed and a second sheet guide which faces the first sheet guide across the sheet conveyance path. The second sheet guide includes a protuberance extending toward the first sheet guide, to locations beyond the guide surface formed by the first sheet guide. When a sheet is located between the first sheet guide and the protuberance of the second sheet guide, the protuberance extends at least a portion of the sheet toward the first sheet guide to bring a part of a surface of the sheet into contact with the first sheet guide.

Abstract: The present disclosure provides electroporation cartridges for single use electroporation as well as electroporation cartridges for automated batch processing, electroporation instruments and systems and methods of electroporation using these devices and systems. In some embodiments, electroporation cartridges comprise an electroporation chamber defined by an elongate body, a first electrode at a proximal end and a second electrode at a distal end of a chamber. Electroporation systems of the disclosure include one or more components including a pulse generator, compartments for placing either flow-through or single use electroporation cartridges, components for storage of cells, cooling and pre-cooling mechanisms, removably insertable modular casings having compartments for holding and arranging electroporation system and reagent components, one or more pumps for moving sample through the system, and processors and controllers.

Abstract: A sheet gripping mechanism includes a first sheet guide including a guide surface facing a sheet conveyance path along which a sheet is to be conveyed and a second sheet guide which faces the first sheet guide across the sheet conveyance path. The second sheet guide includes a protuberance extending toward the first sheet guide, to locations beyond the guide surface formed by the first sheet guide. When a sheet is located between the first sheet guide and the protuberance of the second sheet guide, the protuberance extends at least a portion of the sheet toward the first sheet guide to bring a part of a surface of the sheet into contact with the first sheet guide.

Abstract: A sheet gripping mechanism includes a first sheet guide including a guide surface facing a sheet conveyance path along which a sheet is to be conveyed and a second sheet guide which faces the first sheet guide across the sheet conveyance path. The second sheet guide includes a protuberance extending toward the first sheet guide, to locations beyond the guide surface formed by the first sheet guide. When a sheet is located between the first sheet guide and the protuberance of the second sheet guide, the protuberance extends at least a portion of the sheet toward the first sheet guide to bring a part of a surface of the sheet into contact with the first sheet guide.