Abstract: Embodiments of the present disclosure relate to real-time digitally signing of a virtual object. The real-time digital signing of a virtual object is provided in a multi-user real-time context between signor and signee that enables the signor to perform the real-time digital signing and the signee to visually experience the real-time signing. The real-time digital signing may be provided to the signor and signee in parallel, and/or one or more additional viewers taking part in the digital signing. Upon completion of the digital signing, some embodiments in near-real-time generate a digital asset that is linked to the virtual object modified with the digital signature, which may be assigned to and/or otherwise linked with the signee for subsequent retrieval and/or use.

Abstract: A synthesis method of a targeted drug nCoVshRNA.2ACE2 of a COVID-19 virus, which includes the following steps: designing a consensus RNAi sequence siRNA of the COVID-19 virus and a variant strain thereof; synthesizing two complementary siRNAs into a small hairpin-shaped shRNA with a loop, and synthesizing ACE2 or a cell penetrating peptide ACE2 with a receptor-binding domain (RBD) as a ligand; and ligating the ACE2 to a sense strand and an antisense strand of the shRNA separately to synthesize the nCoVshRNA.2ACE2 including a shRNA region and an ACE2 region. The bivalent ACE2 functions to neutralize the RBD and deliver the shRNA in a targeted manner; an “shRNA-ACE2-RBD-virus” complex bridged by the ACE2 allows the shRNA to enter target cells with virus infection, thereby avoiding a side effect of non-specific delivery of the shRNA to uninfected cells, as well as resisting the variant strain and neutralizing the virus with the ACE2.

Abstract: An organic light emitting diode (OLED) display panel and an electronic device are provided. The OLED display includes an under-screen camera display region and a normal display region surrounding the under-screen camera display region. A pixel density of the under-screen camera display region is less than a pixel density of the normal display region. By lowering the pixel density of the under-screen camera display region, and thereby raising a light transmittance of the under-screen camera display region, an under-screen camera and a true full screen display are realized.

Abstract: An organic light emitting diode (OLED) display panel and an electronic device are provided. The OLED display includes an under-screen camera display region and a normal display region surrounding the under-screen camera display region. A pixel density of the under-screen camera display region is less than a pixel density of the normal display region. By lowering the pixel density of the under-screen camera display region, and thereby raising a light transmittance of the under-screen camera display region, an under-screen camera and a true full screen display are realized.

Abstract: The present invention provides a flexible display panel and a manufacturing method thereof. The flexible display panel includes a substrate made of a flexible material, a thin film transistor substrate disposed on the substrate, a light emitting layer disposed on the thin film transistor substrate, and an encapsulation layer disposed on the light-emitting layer. A bending region is disposed in a display area of the flexible display panel, and a buffer structure having a wave shape is disposed at the bending region on a side of the substrate away from the thin film transistor substrate.

Abstract: The present invention provides a flexible display panel and a manufacturing method thereof. The flexible display panel includes a substrate made of a flexible material, a thin film transistor substrate disposed on the substrate, a light emitting layer disposed on the thin film transistor substrate, and an encapsulation layer disposed on the light-emitting layer. A bending region is disposed in a display area of the flexible display panel, and a buffer structure having a wave shape is disposed at the bending region on a side of the substrate away from the thin film transistor substrate.

Abstract: The disclosure is directed to a failover mechanism for failing over an application service, e.g., a messaging service, from servers in a first region to servers in a second region. Data is stored as shards in which each shard contains data associated with a subset of the users. Data access requests are served by a primary region of the shard. A global shard manager manages failing over the application service from a current primary region of a shard to a secondary region of the shard. The current primary determines whether a criterion for failing over, e.g., a replication lag between the primary and the secondary regions is within a threshold, and if it is within the threshold, the failover process waits until the lag is zero. After the replication lag is zero, the application service is failed over to the second region, which then becomes the primary for the shard.

Abstract: Disclosed herein are a shared memory controller and a method of controlling a shared memory. An embodiment method of controlling a shared memory includes concurrently scanning-in a plurality of read/write commands for respective transactions. Each of the plurality of read/write commands includes respective addresses and respective priorities. Additionally, each of the respective transactions is divisible into at least one beat and at least one of the respective transactions is divisible into multiple beats. The method also includes dividing the plurality of read/write commands into respective beat-level read/write commands and concurrently arbitrating the respective beat-level read/write commands according to the respective addresses and the respective priorities. Concurrently arbitrating yields respective sequences of beat-level read/write commands corresponding to the respective addresses.

Abstract: Disclosed herein are a shared memory controller and a method of controlling a shared memory. An embodiment method of controlling a shared memory includes concurrently scanning-in a plurality of read/write commands for respective transactions. Each of the plurality of read/write commands includes respective addresses and respective priorities. Additionally, each of the respective transactions is divisible into at least one beat and at least one of the respective transactions is divisible into multiple beats. The method also includes dividing the plurality of read/write commands into respective beat-level read/write commands and concurrently arbitrating the respective beat-level read/write commands according to the respective addresses and the respective priorities. Concurrently arbitrating yields respective sequences of beat-level read/write commands corresponding to the respective addresses.

Abstract: A remote control method for a smart TV is provided. The method includes: the smart TV receiving function request information from a portable device in a network based on Universal Plug and Play (UPnP); the smart TV transmitting function information to the portable device in response to the function request information; the smart TV receiving hardware information including control information replied from the portable device according to the function request information; and the smart TV performing an operation control according to the hardware information. Thus, user experiences and interests are enhanced by controlling the smart TV through somatosensory system control or touch control.

Abstract: A remote control method for a smart TV is provided. The method includes: the smart TV receiving function request information from a portable device in a network based on Universal Plug and Play (UPnP); the smart TV transmitting function information to the portable device in response to the function request information; the smart TV receiving hardware information including control information replied from the portable device according to the function request information; and the smart TV performing an operation control according to the hardware information. Thus, user experiences and interests are enhanced by controlling the smart TV through somatosensory system control or touch control.

Abstract: Anti-infection levorotatory optically active compound (S-configuration) of prulifloxacin represented by the following formula (1) and preparation method thereof are disclosed. Said method utilizes levorotatory ulifloxacin as the raw material and the reaction is conducted in organic solvent in the presence of alkaline materials, wherein the reaction temperature is ?20° C.˜60° C. and the reaction time is 15 minutes to 24 hours.

Abstract: Anti-infection levorotatory optically active compound (S-configuration) of prulifloxacin represented by the following formula (1) and preparation method thereof are disclosed. Said method utilizes levorotatory ulifloxacin as the raw material and the reaction is conducted in organic solvent in the presence of alkaline materials, wherein the reaction temperature is ?20° C.˜60° C. and the reaction time is 15 minutes to 24 hours.

Abstract: A compound of formula (I) or its pharmaceutically acceptable salt is prepared by ring opening of osthol under basic condition. The compound of formula (I) or its pharmaceutically acceptable salt has activity of selectively inhibiting tumor cells and lower toxicity, and can be used for preparing anti-tumor drugs.

Abstract: For a portable video player to encode MP3 audio, a first digital signal processor (DSP) encodes digital signals from an analog/digital (A/D) converter into MP3 data, and a controller reads the MP3 data into a nonvolatile memory. To decode MP3 or MP2 audio, the controller reads MP3/2 data from the nonvolatile memory into the first DSP, and the first DSP decodes the MP3/2 data into digital signals that are provided to a digital/analog (D/A) converter. For the portable video player to encode a different type of audio, the first DSP is bypassed and a second DSP encodes digital signals from the A/D converter into audio data and writes the audio data into the nonvolatile memory. To decode this different type of audio, the first DSP is bypassed and the second DSP decodes audio data from the nonvolatile memory into digital signals that are provided to the D/A converter.

Abstract: A method and system for providing a common interface to rule engines. A common rule engine interface system defines a single interface through which any rule engine can be accessed. The common rule engine interface system specifies a premise fact object and a derived fact object that is used to contain the premise facts and derived facts needed for particular rule engine. The common rule engine interface system also provides a rule set identifier object that identifies a particular set of rules. The system also provides an evaluator component that inputs the premise facts as attributes of the premise fact object and inputs a rule set identifier object and outputs the derived facts generated by the identified rule set.

Abstract: Guanine-rich oligonucleotide primers and short telomeric DNA oligonucleotides that serve as non-conventional templates for the synthesis of long, nascent DNA strands are used to screen for pharmaceutical agents. Using the methods of the invention, agents exhibiting antagonistic or agonistic effects on guanine quartet formation can be selected for further study. The invention also provides a predictive assay for cancer in which the level of DNA polymerase activity at a quartet stabilized template is measured. The invention also contributes a method for screening pharmaceutical agents that reduce or inhibit DNA polymerase activity at guanine quartet stabilized templates. The invention provides a method of creating extended DNA molecules from oligonucleotide templates. The invention also provides a method of inhibiting the ageing process in which an oligonucleotide capable of forming non-Watson-Crick structures is used to promote the elongation of telomeres by DNA polymerase.