Patent number: 7858621
Abstract: This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on.
Type:
Grant
Filed:
July 27, 2007
Date of Patent:
December 28, 2010
Assignee:
Amorepacific Corporation
Inventors:
Sun-Young Kim, Jin Kwan Kim, Ki-Wha Lee, Byoung Young Woo, Song Seok Shin, Joo-Hyun Moh, Sung-Il Kim, Yeon Su Jeong, Kyung Min Lim, Jin Kyu Choi, Jun Yong Ha, Hyun-Ju Koh, Young-Ho Park, Young-Ger Suh, Hee-Doo Kim, Hyeung-Geun Park, Uh Taek Oh
Publication number: 20080312234
Abstract: This present invention relates to novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonist; and a pharmaceutical composition containing the same. The present invention provides a pharmaceutical composition for preventing or treating a disease such as pain, migraine, arthralgia, neuralgia, neuropathies, nerve injury, skin disorder, urinary bladder hypersensitiveness, irritable bowel syndrome, fecal urgency, a respiratory disorder, irritation of skin, eye or mucous membrane, stomach-duodenal ulcer, inflammatory diseases, ear disease, heart disease and so on.
Type:
Application
Filed:
July 27, 2007
Publication date:
December 18, 2008
Applicant:
AMOREPACIFIC CORPORATION
Inventors:
Sun-Young KIM, Jin Kwan KIM, Ki-Wha LEE, Byoung Young WOO, Song Seok SHIN, Joo-Hyun MOH, Sung-Il Kim, Yeon Su JEONG, Kyung Min LIM, Jin Kyu CHOI, Jun Yong HA, Hyun-Ju KOH, Young-Ho PARK, Young-Ger SUH, Hee-Doo KIM, Hyeung-Geun PARK, Uh Taek OH