Abstract: A Raman detection system has a Raman spectrometer and a fixing light shielding stand. One end of the fixing light shielding stand is fixedly connected to the Raman spectrometer, and the other end is disposed with an entrance groove for a needle-like SERS probe to enter. A slot for fixing the needle-like SERS probe is formed at an end of the entrance groove, and the slot and the needle-like SERS probe match in shape and size. The Raman detection system has a fixing light shielding device with a dark color groove and a focal length. The groove can be used for limiting the rolling of the curved surface structure of the needle-like SERS probe. A laser can be focused on the curved surface more accurately by adjusting the distance from the instrument detector to the SERS probe.

Abstract: A method for microengineering a gradient structure on a metal surface. A metal surface including at least first, second, and third metal surface regions is exposed to a metal-removing agent. A portion of surface metal atoms is removed by the metal-removing agent in each of the first, second, and third metal surface regions. Sequential metal removal processes expose only the second and third regions to the metal-removing agent, followed by exposing only the third region to the metal-removing agent. A gradient metal surface is formed having different properties in each of the first, second, and third metal surface regions. In a further aspect, quantitative surface-enhanced Raman spectroscopy may be performed using the treated metal surface. An amount of an analyte is determined based on its position in one of the first, second, or third metal surface regions.

Abstract: Disclosed herein is a method of detecting zinc pyrithione (ZPT) in a sample such as water, waste water, shampoos, etc. The method includes steps of, (a) contacting the sample with a substrate having a layer of metal nanostructure deposited thereon thereby coating the layer of metal nanostructure of the substrate with the sample; and (b) subjecting the sample coated substrate to Raman spectroscopy analysis; wherein, the presence of peaks at 575, 829, 1136 and 1545 cm?1 in Raman spectrum indicates the presence of ZPT in the sample. According to embodiments of the present disclosure, the method may detect ZPT in a concentration ranging from 0.1 ng/mL to 8 ?g/mL.

Abstract: A biological sample detection method based on surface-enhanced Raman spectroscopy is disclosed, which relates to the technical field of biological detection. The method includes following operations: washing a substrate used for Raman spectroscopy to obtain a clean substrate; performing surface nanostructuring on the clean substrate to make the clean substrate have a surface Raman enhancement effect, and ultrasonically cleaning the nanostructured substrate with clear water to obtain a surface nanostructured substrate; and inserting the surface nanostructured substrate in a test biological sample, and taking it out after adsorbing the substance to be detected, and then detecting Raman spectrum signals on the surface.

Abstract: A method for treating a surface of a metallic structure, the metallic structure being made of a first metallic material, the method including the steps of: (a) releasing metallic ions from the surface of the metallic structure; and (b) depositing a nano-structured metallic layer onto the surface of the metallic structure from the released metallic ions, wherein the nano-structured metallic layer includes uniform nanoparticles.

Abstract: A metallic structure and a method for surface treatment of a metallic structure. The method includes the steps of: defining a first surface morphology on a surface of the metallic structure using a first surface treatment process; and manipulating the surface using a second surface treatment process to transform the first surface morphology to a second surface morphology; wherein the metallic structure is substantially made of a first metallic material; and wherein the second surface treatment process includes performing at least one cycle of depositing the first metallic material on the surface of the metallic structure and etching away at least some of the first metallic material from the metallic structure.

Abstract: A method for treating a surface of a metallic structure, the metallic structure being made of a first metallic material, the method including the steps of: (a) releasing metallic ions from the surface of the metallic structure; and (b) depositing a nano-structured metallic layer onto the surface of the metallic structure from the released metallic ions, wherein the nano-structured metallic layer includes uniform nanoparticles.

Abstract: A metallic structure and a method for surface treatment of a metallic structure. The method includes the steps of: defining a first surface morphology on a surface of the metallic structure using a first surface treatment process; and manipulating the surface using a second surface treatment process to transform the first surface morphology to a second surface morphology; wherein the metallic structure is substantially made of a first metallic material; and wherein the second surface treatment process includes performing at least one cycle of depositing the first metallic material on the surface of the metallic structure and etching away at least some of the first metallic material from the metallic structure.