Patents by Inventor June P. Davis

June P. Davis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of purifying human factor VIII
    Patent number: 5998589
    Abstract: The invention is a method of purifying Factor VIII comprising the steps of contacting a solution containing Factor VIII with a Factor VIII-binding substrate under conditions sufficient to bind Factor VIII to the substrate, wherein the Factor VIII-binding substrate comprises one or more peptides bound to the substrate, wherein the peptides are selected from the group consisting of SEQ ID NO:1, SEQ ID NO:2, and SEQ ID NO:3, and then eluting the bound Factor VIII.
    Type: Grant
    Filed: July 9, 1999
    Date of Patent: December 7, 1999
    Assignee: Bayer Corporation
    Inventors: Joseph A. Buettner, June P. Davis
  • Peptide ligands for affinity purification of human Factor VIII
    Patent number: 5994310
    Abstract: Peptides which bind Factor VIII are disclosed. The peptides have available Factor VIII binding domains having a Trp-His-Tyr-Tyr-His-Gly, His-Ile-Gln-His-Tyr-His, or His-Gln-Tyr-Gly-Tyr-His sequence. Peptides having at least one of these Factor VIII binding domains are immobilized upon a chromatographic substrate in a preferred embodiment of the invention. This preferred embodiment is useful in a chromatography process to purify human Factor VIII.
    Type: Grant
    Filed: September 3, 1998
    Date of Patent: November 30, 1999
    Assignee: Bayer Corporation
    Inventors: Joseph A. Buettner, June P. Davis