Patents by Inventor June Scott

June Scott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HIV immune stimulating compositions comprising recombinantly expressed pili on bacteria and methods related thereto
    Patent number: 10729762
    Abstract: This disclosure relates to recombinant bacteria, e.g. L. lactis, expressing heterologous pili containing human immunodeficiency virus (HIV) antigens. In certain embodiments, the recombinant bacteria are administered in combination with other HIV antigens, nucleic acids encoding HIV antigens, recombinant virus encoding HIV antigens, anti-viral agents and/or adjuvants in an effective amount to elicit a mucosal immune response against HIV.
    Type: Grant
    Filed: December 20, 2017
    Date of Patent: August 4, 2020
    Assignee: Emory University
    Inventors: Rama Rao Amara, June Scott, Bernard Quigley, Venkateswarlu Chamcha
  • HIV Immune Stimulating Compositions Comprising Recombinantly Expressed Pili on Bacteria and Methods Related Thereto
    Publication number: 20180125967
    Abstract: This disclosure relates to recombinant bacteria, e.g. L. lactis, expressing heterologous pili containing human immunodeficiency virus (HIV) antigens. In certain embodiments, the recombinant bacteria are administered in combination with other HIV antigens, nucleic acids encoding HIV antigens, recombinant virus encoding HIV antigens, anti-viral agents and/or adjuvants in an effective amount to elicit a mucosal immune response against HIV.
    Type: Application
    Filed: December 20, 2017
    Publication date: May 10, 2018
    Inventors: Rama Rao Amara, June Scott, Bernard Quigley, Venkateswarlu Chamcha
  • METHODS AND COMPOSITIONS FOR THE DISPLAY OF POLYPEPTIDES ON THE PILI OF GRAM- POSITIVE BACTERIA
    Publication number: 20160304567
    Abstract: Provided herein are methods and compositions for the display of polypeptides of interest on the tip of pili of Gram-positive bacteria. According to the present invention, the polypeptide of interest is amino terminal to a Gram-positive bacterial pilus tip protein or an active variant or fragment thereof, wherein the active variant or fragment comprises a cleaved cell wall sorting signal (CWSS) motif. The Gram-positive bacterium displaying a polypeptide of interest on the tip of pili that are disclosed herein are useful, for example, in methods for immunizing a subject with an antigen and methods for removing contaminants from a composition.
    Type: Application
    Filed: October 14, 2014
    Publication date: October 20, 2016
    Inventors: JUNE SCOTT, DOROTHEA ZÄHNER, BERNARD QUIGLEY
  • Methods and Compositions for the Display of Polypeptides on the Pili of Gram-Positive Bacteria
    Publication number: 20110189236
    Abstract: Provided herein are methods and compositions for the display of polypeptides of interest on the tip of pili of Gram-positive bacteria. According to the present invention, the polypeptide of interest is amino terminal to a Gram-positive bacterial pilus tip protein or an active variant or fragment thereof, wherein the active variant or fragment comprises a cleaved cell wall sorting signal (CWSS) motif. The Gram-positive bacterium displaying a polypeptide of interest on the tip of pili that are disclosed herein are useful, for example, in methods for immunizing a subject with an antigen and methods for removing contaminants from a composition.
    Type: Application
    Filed: May 8, 2009
    Publication date: August 4, 2011
    Applicant: EMORY UNIVERSITY
    Inventors: June Scott, Dorothea Zahner, Bernard Quigley