Abstract: The present application provides a method of treating tumor: administrating a HER2 inhibitor, and said subject comprises an alteration in a protein HER2, CDK12. The present application provides a medicinal product comprising: the HER2 inhibitor and the multiple CDK inhibitor, showing significant inhibition of tumor cell growth.

Abstract: The present disclosure provides a method and system for detecting exhaust emissions of a vehicle equipped with an ignition engine based on big data of remote sensing. The system includes: a vehicle emission measuring instrument, a host computer, an information display instrument, a vehicle driving state tester, a weather monitor, a license plate camera and a vehicle emission monitoring platform. The vehicle emission measuring instrument, the information display instrument, the vehicle driving state tester, the weather monitor and the license plate camera communicate with the host computer. The host computer is connected to the vehicle emission monitoring platform via the Internet. The present disclosure acquires pollutant concentrations in the vehicle emissions through the detection system, divides a vehicle specific power (VSP) into multiple bins, performs statistical analysis and evaluation on the vehicle emissions according to different vehicle types, and determines high-emission vehicles.

Abstract: The present disclosure provides a system and method for monitoring diesel vehicle emissions based on big data of remote sensing. The monitoring system includes a vehicle remote sensing data monitoring platform, a host computer, an emission remote sensing instrument, a vehicle driving state monitor, an information display screen and a license plate camera. The emission remote sensing instrument is used to acquire information of a pollutant in an exhaust plume. The vehicle driving state monitor is used to acquire a vehicle speed and acceleration. The license plate camera is used to capture license plate information. The host computer is used to process and calculate vehicle cycle and emission information. The vehicle remote sensing data monitoring platform is used to determine a high-emission vehicle, and pre-store information of all diesel vehicles, different driving cycle bins of each type of diesel vehicles and high-emission thresholds set for different bins.

Abstract: The present disclosure provides a method and system for detecting exhaust emissions of a vehicle equipped with an ignition engine based on big data of remote sensing. The system includes: a vehicle emission measuring instrument, a host computer, an information display instrument, a vehicle driving state tester, a weather monitor, a license plate camera and a vehicle emission monitoring platform. The vehicle emission measuring instrument, the information display instrument, the vehicle driving state tester, the weather monitor and the license plate camera communicate with the host computer. The host computer is connected to the vehicle emission monitoring platform via the Internet. The present disclosure acquires pollutant concentrations in the vehicle emissions through the detection system, divides a vehicle specific power (VSP) into multiple bins, performs statistical analysis and evaluation on the vehicle emissions according to different vehicle types, and determines high-emission vehicles.