Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.

Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.

Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.

Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.

Abstract: A bogie of a rail vehicle includes a frame, which includes two box-shaped longitudinal beam main bodies and a transverse beam main body; a wheelset, which includes an axle box, an axle and wheels mounted at two ends of the axle; a drive system, which at least includes a gearbox and a drive motor. Practice has proved that the two axle boxes arranged on the inner sides of the two longitudinal beam main bodies can reduce a volume by about 10%, and reduce a weight by about 10% to 15%, which can further reduce air resistance, and realize energy saving and emission reduction. The longitudinal beam main body is located on an inner side of a wheel, a span of the two the longitudinal beam main bodies is reduced, and the torsional rigidity of the frame is reduced, which is beneficial to improving a curve passing capacity.

Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.

Abstract: A monomer capable forming a polymer through ring-opening metathesis polymerization and capable of depolymerization thereafter through ring-closing metathesis, wherein the monomer comprises a cycloalkene having a fused ring attached thereto to form a cycloalkene-fused ring monomer, wherein the fused ring decreases the ring strain energy of the cycloalkene to a lower ring strain energy state of 5.3 kcal/mol or lower as compared to the same cycloalkene without the fused ring having a ring strain energy above 5.3 kcal/mol and wherein the cycloalkene-fused ring monomer is capable of isomerization into a higher ring strain energy state before polymerization and method of synthesizing the monomer. The monomer is further capable of forming chemically recyclable to monomers block copolymers.

Abstract: A bogie of a rail vehicle includes a frame, which includes two box-shaped longitudinal beam main bodies and a transverse beam main body; a wheelset, which includes an axle box, an axle and wheels mounted at two ends of the axle; a drive system, which at least includes a gearbox and a drive motor. Practice has proved that the two axle boxes arranged on the inner sides of the two longitudinal beam main bodies can reduce a volume by about 10%, and reduce a weight by about 10% to 15%, which can further reduce air resistance, and realize energy saving and emission reduction. The longitudinal beam main body is located on an inner side of a wheel, a span of the two the longitudinal beam main bodies is reduced, and the torsional rigidity of the frame is reduced, which is beneficial to improving a curve passing capacity.

Abstract: A method for manufacturing an aluminum alloy vehicle body includes the following steps: vehicle body part molding, including: profile stretch-bending and machining; vehicle body frame assembly welding, including: performing assembly welding on a lower vehicle body, left and right side panels, and front and rear roof crossbeams; outer panel manufacturing, including: manufacturing an outer panel by injection molding; and whole vehicle assembling, including: assembling interior trim parts and the outer panel to a vehicle body frame, and assembling chassis parts to the vehicle body frame. The vehicle body parts and the vehicle body frame are made of an aluminum alloy material, and the outer panel is made of a non-metallic composite material.

Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.

Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.

Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.

Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.

Abstract: A reactive navy to black dye composition comprises component A and component B, wherein component A is selected from one or more compounds of formula (I), component B is selected from one or more compounds of formula (II); D1 and D2 are each independently a group represented by the following formula (a) or (b) or (c); R1-R12 are each independently selected from the group consisting of H, linear or branched C1˜C4 alkyl, C1˜C4 alkoxy and sulfo; m, n=0-3, and every R3 is each independently selected from the group consisting of amino, sulfo, ureido, C1˜C4 alkanoylamino, C1˜C4 alkoxy and C1˜C4 alkyl, every R6 is each independently selected from the group consisting of amino, hydroxyl and sulfo; X1-X3 are each independently selected from the group consisting of H, C1˜C4 alkyl, C1˜C4 alkoxy, —SO2Y1, —NHCO(CH2)pSO2Y2 and —CONH(CH2)qSO2Y3, and at least one of D1 and D2 contains a fiber-reactive group, p, q=1-3, and Y1˜Y5 are each independently selected from the group consisting of —CH?CH2, —C2H4OSO3H and —CH2CH2Cl.

Abstract: A method for manufacturing an aluminum alloy vehicle body includes the following steps: vehicle body part molding, including: profile stretch-bending and machining; vehicle body frame assembly welding, including: performing assembly welding on a lower vehicle body, left and right side panels, and front and rear roof crossbeams; outer panel manufacturing, including: manufacturing an outer panel by injection molding; and whole vehicle assembling, including: assembling interior trim parts and the outer panel to a vehicle body frame, and assembling chassis parts to the vehicle body frame. The vehicle body parts and the vehicle body frame are made of an aluminum alloy material, and the outer panel is made of a non-metallic composite material.

Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.

Abstract: A reactive navy to black dye composition comprises component A and component B, wherein component A is selected from one or more compounds of formula (I), component B is selected from one or more compounds of formula (II); D1 and D2 are each independently a group represented by the following formula (a) or (b) or (c); R1-R?2 are each independently selected from the group consisting of H, linear or branched C1˜C4 alkyl, C1˜C4 alkoxy and sulfo; m, n=0-3, and every R3 is each independently selected from the group consisting of amino, sulfo, ureido, C1˜C4 alkanoylamino, C1˜C4 alkoxy and C1˜C4 alkyl, every R6 is each independently selected from the group consisting of amino, hydroxyl and sulfo; X1-X3 are each independently selected from the group consisting of H, C1˜C4 alkyl, C1˜C4 alkoxy, —SO2Y1, —NHCO(CH2)pSO2Y2 and —CONH(CH2)qSO2Y3, and at least one of D1 and D2 contains a fiber-reactive group, p, q=1-3, and Y1˜Y5 are each independently selected from the group consisting of —CH?CH2, —C2H4OSO3H and —CH2CH2Cl.

Abstract: The invention provides processes of purifying a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-251 described herein. The processes include a solvent exchange step before a freeze-drying (lyophilization) step.

Abstract: The invention provides processes of preparing a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-249 described herein.

Abstract: The invention provides processes of preparing a peptide including a GCC agonist sequence selected from the group consisting of SEQ ID NOs: 1-249 described herein.