Abstract: The present disclosure relates to a GLP-1 receptor agonist compound, and a novel salt thereof having excellent in vivo solubility, stability, and bioavailability, a preparation method thereof, and a pharmaceutical composition comprising the same.

Abstract: Disclosed is a method and apparatus for an instant messaging service. An operating method of a server providing an instant messaging service includes extracting information on a channel to which a notification message corresponding to a user account is transmitted, determining a type of notification message based on metadata of the notification message, generating a news feed corresponding to the notification message based on the type of the notification message, and providing an aggregation page of the news feed linked to a chatroom of the channel to a terminal of the user account.

Abstract: Disclosed is an apparatus for processing a substrate, the apparatus including: a chamber having a processing space for processing a substrate; a support unit disposed in the processing space and for supporting the substrate; a nozzle for discharging a treatment solution onto the substrate when processing the substrate; and a liquid supply unit for supplying the nozzle with the treatment solution, in which the liquid supply unit includes: a liquid supply source for supplying the treatment solution; a supply line connected between the liquid supply source and the nozzle; a supply valve installed on the supply line and opening and closing a passage of the supply line; a discharge line connected to the supply line downstream of the supply valve and discharging the treatment solution from the supply line; and a drain valve installed on the discharge line and opening and closing a passage of the discharge line.

Abstract: Disclosed is a method and apparatus for an instant messaging service. An operating method of a server providing an instant messaging service includes generating an access path to a group chatroom linked to a channel. The method includes providing an access point to the group chatroom through a page of the channel based on the access path. The method includes providing information on the channel through the group chatroom. The method includes posting content based on a message transmitted through the group chatroom on the page of the channel.

Abstract: Disclosed is a molded article, and more particularly a molded article for a vehicle interior material including a thermoplastic resin composition having reduced birefringence while maintaining the superior transmittance and impact strength of existing polycarbonate resin by including a first resin including a polycarbonate resin and a second resin having a difference in refractive index of 0.05 or less from the first resin and a transmittance of 90% or more.

Abstract: Provided are a polyethylene yarn having improved weaving properties and a functional fabric including the same, and more particularly, a polyethylene yarn which may provide a user with an appropriate cool feeling and excellent wearability and allow manufacture of a fabric having a very low fluff occurrence frequency, and a functional fabric including the same are provided. The polyethylene yarn has a polydispersity index (PDI) of 5 or more and 20 or less, a strength of 1.5 to 10 g/d as measured according to ASTM D2256, and an elongation at maximum force of 10 to 50%.

Abstract: The present invention relates to a shaped cross-sectional polyethylene yarn and a functional fabric including the same, and more particularly, to a shaped cross-sectional polyethylene yarn by which a fabric having a cooling sensation and sweat absorption and quick drying properties may be manufactured, and a functional fabric including the same. A polyethylene yarn according to the present invention includes a filament having a central body and two or more protrusions protruding from the central body based on a cross section perpendicular to a longitudinal direction, wherein a degree of crystallinity of the polyethylene yarn is 56 to 85%.

Abstract: The present invention relates to a dope dyed polyethylene yarn and a functional fabric including the same, and more particularly, to a dope dyed polyethylene yarn having excellent color uniformity and a functional fabric including the same. A dope dyed polyethylene yarn according to the present invention contains a pigment, wherein L*, a* and b* measured under the following measurement condition satisfy the following expression: [Measurement condition] a measurement region is formed by winding the dope dyed polyethylene yarn around a planar substrate, computer color matching (CCM) is measured in the measurement region, and the CCM is measured at least n times (n is a natural number of 50 or more) every time the dope dyed polyethylene yarn is wound around the substrate 70 turns, ( C max - C min ) / C aver × 1 ? 0 ? 0 ? 1 ? 5 [ Expression ] wherein Cmax, Cmin, and Caver represent maximum, minimum, and average values of any one selected from L*, a*, and b*, respectively.

Abstract: Provided are a polyethylene yarn having improved dimensional stability and a functional fabric including the same, and more particularly, a polyethylene yarn having improved dimensional stability, which may prevent shape deformation after post-processing such as weaving and cutting, and a functional fabric including the yarn to provide a user with a cool feeling are provided.

Abstract: The present invention relates to cell-derived vesicles with increased cellular uptake capacity and a method for producing same. The cell-derived vesicles of the present invention are produced by migrating cells to micropores, and exhibit the characteristic of expressing a protein marker that is different from that of exosomes naturally secreted by cells. The cell-derived vesicles with increased cellular uptake capacity, according to the present invention, have remarkably superior cellular uptake capacity as compared to natural exosomes secreted by cells, and thus can be effectively used to deliver various active substances, such as drugs and marker substances, into target cells.

Abstract: The present invention relates to a portable probe for photoacoustic tomography, capable of performing line-by-line scanning or area-by-area scanning by using a small number of light inputs; and a real-time photoacoustic tomography device. The probe for photoacoustic tomography includes: a lens receiving light inputs from an optical fiber so as to make the same proceed as small diameter parallel light; a Powell lens receiving the small diameter parallel light and generating a line beam of a predetermined thickness, and allowing energy dispersed on a line to be uniform on the entire line; a lens making the line beam pass therethrough such that the line beam has a predetermined width and a reduced thickness so as to be line-focused at a target area; an acoustic reflection glass for separating, from a light path, an acoustic wave outputted from the target area; and an acoustic measurement unit for measuring acoustic strength.

Abstract: Disclosed are novel compounds of Chemical Formula 1, optical isomers of the compounds, and pharmaceutically acceptable salts of the compounds or the optical isomers. The compounds, isomers, and salts exhibit excellent activity as GLP-1 receptor agonists. In particular, they, as GLP-1 receptor agonists, exhibit excellent glucose tolerance, thus having a great potential to be used as therapeutic agents for metabolic diseases. Moreover, they exhibit excellent pharmacological safety for cardiovascular systems.

Abstract: Provided is a method of differentiating a pluripotent stem cell-derived hemogenic endothelial cell into a lymphoid lineage blood cell, enabling a hemogenic endothelial cell to be cultured for a long period of time so as to be induced into a lymphoid lineage blood cell, thereby facilitating induction of generation of immune cells such as T cells, B cells, and NK cells.

Abstract: Provided are a high-strength polyethylene yarn having an improved shrinkage rate and a method for manufacturing the same. More particularly, a high-strength polyethylene yarn which has a specific microstructure and has an improved shrinkage rate to allow manufacture of high-density fabric, and a method for manufacturing the same are provided.

Abstract: The present invention relates to a functional fabric. More specifically, the present invention relates to a functional fabric, which causes no skin irritation, has excellent washing durability and antibacterial and deodorizing properties, quickly discharges moisture generated from the human body, such as sweat or breath, and quickly diffuses heat.

Abstract: The present invention provides a novel compound represented by Chemical Formula 2, or a pharmaceutically acceptable salt thereof. The novel compound according to the present invention exhibits an excellent acid secretion inhibitory effect.

Abstract: Provided is a method of treating cancer, particularly cancers associated with an overexpression of polo-like kinase (Plk1), comprising administering a compound of formula (I) or a pharmaceutically acceptable salt thereof in which ring A, X1, X2, X3, X4, X5, R2, R3, R4, n, bond a, and bond b are described herein. Exemplary compounds of formula (I) and pharmaceutically acceptable salts thereof, especially those that selectively inhibit the polo box domain of Plk1, also are provided.

Abstract: Provided is a cut-resistant polyethylene yarn, and more particularly, a cut-resistant polyethylene yarn which allows manufacture of a product having excellent cut resistance and providing excellent wearability.

Abstract: Provided is a cut-resistant polyethylene yarn, and more particularly, a cut-resistant polyethylene yarn which allows manufacture of a product having both excellent cut resistance and excellent wear resistance.

Abstract: Provided is a polyethylene yarn having improved post-processability, and more particularly, a polyethylene yarn which maintains excellent mechanical properties even in a harsh environment such as a high temperature to have improved post-processability such as dyeing or coating is provided.