Abstract: The present invention relates to a pharmaceutical composition for prevention or treatment of rheumatoid arthritis, the composition comprising, as an active ingredient, human nasal inferior turbinate-derived stem cells in which the expression of specific genes is increased or decreased. The human nasal inferior turbinate-derived stem cells exhibiting a therapeutic effect on arthritis were identified to specifically have an increased expression level of HAS2, CXCL1, or KRTAP1-5 gene or a decreased expression level of GSTT2B or C4B gene. Thus, by taking advantage of this feature, only stem cells that have a therapeutic effect on arthritis can be selected for use in treating rheumatoid arthritis, with the expectation of enhancing the therapeutic effect. Furthermore, it is expected that a method for selecting stem cells useful as a therapeutic agent for rheumatoid arthritis can be provided.

Abstract: The present invention relates to a pharmaceutical composition for treating cartilage damage, the composition comprising nasal septum chondrocytes (NSCs) as an active ingredient, and a method for producing the NSCs into a spheroidal shape. The NSCs enable the expression of type II collagen which is a constituent component of cartilage, and SOX9 which is involved in chondrogenic differentiation, and an excellent cartilage treatment effect was shown as a result of administrating spheroidal NSCs to an animal model of cartilage damage, and thus the pharmaceutical composition and the method for producing the NSCs, according to the present invention, may be useful employed in the field of autologous chondrocyte implantation.

Abstract: According to various embodiments of the present disclosure, an electronic device may include: an external housing having a through-hole that connects the inside and the outside of the portable electronic device; a first structure that is accommodated in a space of the external housing and has an opening and a passage, wherein the opening is disposed adjacent to the through-hole and the passage extends in a first direction and is connected to the opening; a second structure that is accommodated in the space of the external housing and disposed adjacent to the first structure, and has a portion directed toward the through-hole; and a material that is located on the portion of the second structure so as to be visible from the outside through the through-hole and changes color in reaction to contact of a fluid. In addition, various other embodiments can be made.

Abstract: According to various embodiments of the present disclosure, an electronic device may include: an external housing having a through-hole that connects the inside and the outside of the portable electronic device; a first structure that is accommodated in a space of the external housing and has an opening and a passage, wherein the opening is disposed adjacent to the through-hole and the passage extends in a first direction and is connected to the opening; a second structure that is accommodated in the space of the external housing and disposed adjacent to the first structure, and has a portion directed toward the through-hole; and a material that is located on the portion of the second structure so as to be visible from the outside through the through-hole and changes color in reaction to contact of a fluid. In addition, various other embodiments can be made.

Abstract: An insert injection-molded case that provides a better appearance and a reduced defective rate of manufacture can be utilized for a number of products, including but not limited to a cover for portable communication devices. The case preferably includes: a metal plate having one or more fixing portions coupled to fixing members formed in a mold respectively; an injection-molded case body injection molded with the metal plate; and one or more holding portions formed in the injection-molded case body during the injection molding and coupled to the fixing members respectively to prevent deflection of the injection-molded case body caused during a cooling operation after the injection molding.

Abstract: An insert injection-molded case that provides a better appearance and a reduced defective rate of manufacture can be utilized for a number of products, including but not limited to a cover for portable communication devices. The case preferably includes: a metal plate having one or more fixing portions coupled to fixing members formed in a mold respectively; an injection-molded case body injection molded with the metal plate; and one or more holding portions formed in the injection-molded case body during the injection molding and coupled to the fixing members respectively to prevent deflection of the injection-molded case body caused during a cooling operation after the injection molding.