Abstract: A method to produce aqueous droplets in oil and to manipulate the droplets for storage in the microfluidic device for certain amount of time to accumulate detectable amount of product produced by a single copy or plural copies of enzyme enclosed in the droplets, and to detect and measure the biomarkers in the antibody binding assay is disclosed. The method comprises: (1) generation of droplets in the microfluidic device, (2) storage of droplets in the microfluidic device, (3) measurement of activity of a single copy or plural copies of enzyme in the droplets, (4) individual molecule-counting immunoassay using the droplets. Applications can include the single molecule counting immunoassay, a platform for extremely high through digital PCR, a platform for directed evolution at individual molecule resolutions, nanoparticles synthesis, biodegradable polymer particle production and single molecule analysis.

Abstract: A liquid crystal display having electrodes on a single substrate. A transparent planar electrode elongated in the transverse direction is formed on the inner surface of a substrate, and an insulating film is deposited thereon. A plurality of linear electrodes, which are elongated in the longitudinal direction and either transparent or opaque, are formed on the insulating film. Potential difference between the planar and the linear electrodes generated by applying voltages to the electrodes yields an electric field. The electric field is symmetrical with respect to the longitudinal central line of the linear electrodes, and has parabolic or semi-elliptical lines of force having a center on a boundary line between the planar and the linear electrodes. The line of force on the planar and the linear electrodes and on the boundary line between the planar and the linear electrodes has the vertical and the horizontal components, and the liquid crystal molecules are re-arranged to have a twist angle and a tilt angle.

Abstract: A liquid crystal display having electrodes on a single substrate. A transparent planar electrode elongated in the transverse direction is formed on the inner surface of a substrate, and an insulating film is deposited thereon. A plurality of linear electrodes, which are elongated in the longitudinal direction and either transparent or opaque, are formed on the insulating film. Potential difference between the planar and the linear electrodes generated by applying voltages to the electrodes yields an electric field. The electric field is symmetrical with respect to the longitudinal central line of the linear electrodes, and has parabolic or semi-elliptical lines of force having a center on a boundary line between the planar and the linear electrodes. The line of force on the planar and the linear electrodes and on the boundary line between the planar and the linear electrodes has the vertical and the horizontal components, and the liquid crystal molecules are re-arranged to have a twist angle and a tilt angle.

Abstract: Two electrodes parallel to each other are formed on one of two substrates, homeotropic alignment films are formed on the substrates and a liquid crystal material having positive dielectric anisotropy is injected between the substrates. When a voltage is applied to the two electrodes, a parabolic electric field between the electrodes drives the liquid crystal molecules. Since the generated electric field is symmetrical with respect to the boundary-plane equal distance from each of the two electrodes, the liquid crystal molecules are symmetrically aligned with respect to the boundary-plane, and the optical characteristic is compensated in both regions divided by the boundary-plane, thereby obtaining a wide viewing angle. The electric field does not exert influences on the liquid crystal molecules on the boundary-plane since the electric field on the boundary-plane is parallel to the substrates and perpendicular to the two electrodes; and thus, it is perpendicular to the liquid crystal molecules.

Abstract: A liquid crystal display having electrodes on a single substrate. A transparent planar electrode elongated in the transverse direction is formed on the inner surface of a substrate, and an insulating film is deposited thereon. A plurality of linear electrodes, which are elongated in the longitudinal direction and either transparent or opaque, are formed on the insulating film. Potential difference between the planar and the linear electrodes generated by applying voltages to the electrodes yields an electric field. The electric field is symmetrical with respect to the longitudinal central line of the linear electrodes, and has parabolic or semi-elliptical lines of force having a center on a boundary line between the planar and the linear electrodes. The line of force on the planar and the linear electrodes and on the boundary line between the planar and the linear electrodes has the vertical and the horizontal components, and the liquid crystal molecules are re-arranged to have a twist angle and a tilt angle.

Abstract: Two electrodes parallel to each other are formed on one of two substrates, homeotropic alignment films are formed on the substrates and a liquid crystal material having positive dielectric anisotropy is injected between the substrates. When a voltage is applied to the two electrodes, a parabolic electric field between the electrodes drives the liquid crystal molecules. Since the generated electric field is symmetrical with respect to the boundary-plane equal distance from each of the two electrodes, the liquid crystal molecules are symmetrically aligned with respect to the boundary-plane, and the optical characteristic is compensated in both regions divided by the boundary-plane, thereby obtaining a wide viewing angle. The electric field does not exert influences on the liquid crystal molecules on the boundary-plane since the electric field on the boundary-plane is parallel to the substrates and perpendicular to the two electrodes; and thus, it is perpendicular to the liquid crystal molecules.

Abstract: Two electrodes parallel to each other are formed on one of two substrates, homeotropic alignment films are formed on the substrates and a liquid crystal material having positive dielectric anisotropy is injected between the substrates. When a voltage is applied to the two electrodes, a parabolic electric field between the electrodes drives the liquid crystal molecules. Since the generated electric field is symmetrical with respect to the boundary-plane equal distance from each of the two electrodes, the liquid crystal molecules are symmetrically aligned with respect to the boundary-plane, and the optical characteristic is compensated in both regions divided by the boundary-plane, thereby obtaining a wide viewing angle. The electric field does not exert influences on the liquid crystal molecules on the boundary-plane since the electric field on the boundary-plane is parallel to the substrates and perpendicular to the two electrodes and thus, it is perpendicular to the liquid crystal molecules.

Abstract: A liquid crystal display having electrodes on a single substrate. A transparent planar electrode elongated in the transverse direction is formed on the inner surface of a substrate, and an insulating film is deposited thereon. A plurality of linear electrodes, which are elongated in the longitudinal direction and either transparent or opaque, are formed on the insulating film. Potential difference between the planar and the linear electrodes generated by applying voltages to the electrodes yields an electric field. The electric field is symmetrical with respect to the longitudinal central line of the linear electrodes, and has parabolic or semi-elliptical lines of force having a center on a boundary line between the planar and the linear electrodes. The line of force on the planar and the linear electrodes and on the boundary line between the planar and the linear electrodes has the vertical and the horizontal components, and the liquid crystal molecules are re-arranged to have a twist angle and a tilt angle.

Abstract: The present invention relates generally to microfluidic structures, and more specifically, to microfluidic structures and methods including microreactors for manipulating fluids and reactions. In some embodiments, structures and methods for manipulating many (e.g., 1000) fluid samples, i.e., in the form of droplets, are described. Processes such as diffusion, evaporation, dilution, and precipitation can be controlled in each fluid sample. These methods also enable conditions within the fluid samples (e.g., concentration) to be controlled. Manipulation of fluid samples can be useful for a variety of applications, including testing for reaction conditions, e.g., in crystallization, chemical, and biological assays.

Abstract: A liquid crystal display having electrodes on a single substrate. A transparent planar electrode elongated in the transverse direction is formed on the inner surface of a substrate, and an insulating film is deposited thereon. A plurality of linear electrodes, which are elongated in the longitudinal direction and either transparent or opaque, are formed on the insulating film. Potential difference between the planar and the linear electrodes generated by applying voltages to the electrodes yields an electric field. The electric field is symmetrical with respect to the longitudinal central line of the linear electrodes, and has parabolic or semi-elliptical lines of force having a center on a boundary line between the planar and the linear electrodes. The line of force on the planar and the linear electrodes and on the boundary line between the planar and the linear electrodes has the vertical and the horizontal components, and the liquid crystal molecules are re-arranged to have a twist angle and a tilt angle.

Abstract: The present invention relates generally to microfluidic structures, and more specifically, to microfluidic structures and methods including microreactors for manipulating fluids and reactions. In some embodiments, structures and methods for manipulating many (e.g., 1000) fluid samples, i.e., in the form of droplets, are described. Processes such as diffusion, evaporation, dilution, and precipitation can be controlled in each fluid sample. These methods also enable conditions within the fluid samples (e.g., concentration) to be controlled. Manipulation of fluid samples can be useful for a variety of applications, including testing for reaction conditions, e.g., in crystallization, chemical, and biological assays.

Abstract: A liquid crystal display having electrodes on a single substrate includes a transparent planar electrode elongated in the transverse direction formed on the inner surface of the substrate, and an insulating film is deposited thereon. A plurality of linear electrodes, which are elongated in the longitudinal direction and either transparent or opaque, are formed on the insulating film. When voltages applied, the electric field is symmetrical with respect to the longitudinal central line of the linear electrodes and the longitudinal central line of a region between the linear electrodes, and has parabolic or semi-elliptical lines of force having a center on a boundary line between the planar and the linear electrodes.

Abstract: A liquid crystal display having electrodes on a single substrate. A transparent planar electrode elongated in the transverse direction is formed on the inner surface of a substrate, and an insulating film is deposited thereon. A plurality of linear electrodes, which are elongated in the longitudinal direction and either transparent or opaque, are formed on the insulating film. Potential difference between the planar and the linear electrodes generated by applying voltages to the electrodes yields an electric field. The electric field is symmetrical with respect to the longitudinal central line of the linear electrodes, and has parabolic or semi-elliptical lines of force having a center on a boundary line between the planar and the linear electrodes. The line of force on the planar and the linear electrodes and on the boundary line between the planar and the linear electrodes has the vertical and the horizontal components, and the liquid crystal molecules are re-arranged to have a twist angle and a tilt angle.

Abstract: Two electrodes parallel to each other are formed on one of two substrates, homeotropic alignment films are formed on the substrates and a liquid crystal material having positive dielectric anisotropy is injected between the substrates. When a voltage is appled to the two electrodes, a parabolic electric field between the electrodes drives the liquid crystal molecules. Since the generated electric field is symmetrical with respect to the boundary-plane equal distance from each of the two electrodes, the liquid crystal molecules are symmetrically aligned with respect to the boundary-plane, and the optical characteristic is compensated in both regions divided by the boundary-plane, thereby obtaining a wide viewing angle. The electric field does not exert influences on the liquid crystal molecules on the boundary-plane since the electric field on the boundary-plane is parallel to the substrates and perpendicular to the two electrodes and thus, it is perpendicular to the liquid crystal molecules.

Abstract: A liquid crystal display includes a first substrate having a plurality of pixels, a second substrate facing the first substrate, polarizing plates attached to outer surfaces of the two substrates, and a liquid crystal material injected into the gap between the two substrates, molecules of the liquid crystal material being initially aligned perpendicularly to the substrates. Each pixel is divided into a plurality of domains distinguished by an average alignment direction of liquid crystal molecules included therein when an electric field is applied to the liquid crystal material. On average, liquid crystal molecules located at an edge of the domains are aligned symmetrically to each other with respect to a boundary of the domains. Polarizing directions of the polarizing plates are either perpendicular or parallel to each other, but neither parallel nor perpendicular to at least one of the average alignment directions of the liquid crystal molecules of the domains.

Abstract: Two electrodes in parallel with each other are formed on one of two substrates, homeotropic alignment films are formed on the substrates and a liquid crystal material having positive dielectric anisotropy is injected between the substrates. When the voltage is applied to the two electrodes, a parabolic electric field between the electrodes drives the liquid crystal molecules. Since the electric field generated is symmetrical with respect to the boundary-plane equal distance from each of the two electrodes, the liquid crystal molecules are symmetrically aligned with respect to the boundary-plane. The electric field does not exert influences the liquid crystal molecules on the boundary-plane since the electric field on the boundary-plane is parallel with the substrates and perpendicular to the two electrodes; and thus, it is perpendicular to the liquid crystal molecules.

Abstract: Disclosed is a liquid crystal display comprising a first substrate including a first electrode; a second substrate including a second electrode, the second substrate being arranged substantially in parallel with the first substrate and with a predetermined gap therebetween; a liquid crystal layer formed by injecting liquid crystal material between the first and second substrates, long axes of liquid crystal molecules of the liquid crystal layer being arranged vertically to the first substrate and the second substrate; and first and second orientation layers formed on the first substrate and the second substrate, respectively, and providing an orientation force to the liquid crystal molecules such that the long axes of the liquid crystal molecules are slanted or twisted by 0 to 10°.

Abstract: Two electrodes parallel to each other are formed on one of two substrates, homeotropic alignment films are formed on the substrates and a liquid crystal material having positive dielectric anisotropy is injected between the substrates. When a voltage is applied to the two electrodes, a parabolic electric field between the electrodes drives the liquid crystal molecules. Since the generated electric field is symmetrical with respect to the boundary-plane equal distance from each of the two electrodes, the liquid crystal molecules are symmetrically aligned with respect to the boundary-plane, and the optical characteristic is compensated in both regions divided by the boundary-plane, thereby obtaining a wide viewing angle. The electric field does not exert influences on the liquid crystal molecules on the boundary-plane since the electric field on the boundary-plane is parallel to the substrates and perpendicular to the two electrodes: and thus, it is perpendicular to the liquid crystal molecules.

Abstract: An in-plane switching type liquid crystal display device includes opposed first and second panels, defining a gap therebetween, the first and second panels including first and second electrodes, spaced laterally apart in the gap. A quantity of a liquid crystal material is disposed in the gap between the first and second panels, wherein a product of a refractive anisotropy of the liquid crystal material and the gap between the first and second panels is in a range between 0.36 &mgr;m and 0.45 &mgr;m. Preferably, the gap between the first and second panels is in a range between 4 &mgr;m and 5 &mgr;m, and the refractive anisotropy is in a range between 0.067 and 1.1016.

Abstract: Two electrodes parallel to each other are formed on one of two substrates, homeotropic alignment films are formed on the substrates and a liquid crystal material having positive dielectric anisotropy is injected between the substrates. When a voltage is applied to the two electrodes, a parabolic electric field between the electrodes drives the liquid crystal molecules. Since the generated electric field is symmetrical with respect to the boundary-plane equal distance from each of the two electrodes, the liquid crystal molecules are symmetrically aligned with respect to the boundary-plane, and the optical characteristic is compensated in both regions divided by the boundary-plane, thereby obtaining a wide viewing angle. The electric field does not exert influences on the liquid crystal molecules on the boundary-plane since the electric field on the boundary-plane is parallel to the substrates and perpendicular to the two electrodes: and thus, it is perpendicular to the liquid crystal molecules.