Abstract: Disclosed is a hand and foot assistive device capable of taking care of a lesion area of a patient's hand or foot. The device includes a carrier and a measurement module. The carrier is in contact with at least one of the patient's hands and feet. The measurement module is installed at the carrier and includes a sensing unit, a processing unit and a communication unit. The processing unit is coupled to the sensing unit and the communication unit. The sensing unit is disposed adjacent to or overlapped with the lesion area. The sensing unit detects the lesion area to selectively generate a sensing signal. The processing unit processes the sensing signal and sends the sensing signal to communication unit, and the communication unit sends the sensing signal to the outside of the carrier. The sensing unit is provided for detecting a humidity change of the lesion area.