Abstract: The present invention relates to a pharmaceutical composition for the prevention or treatment of cancer, comprising a DEAD-box helicase 54 (DDX54) inhibitor and a cancer immunotherapy agent, and to a combination therapy of cancer immunotherapy. The DDX54 inhibitor according to the present invention can enhance the efficacy of cancer immunotherapy when used in combination with a cancer immunotherapy agent, and the composition containing the DDX54 inhibitor and a cancer immunotherapy agent inhibits proliferation of cancer, which is a key characteristic thereof, and simultaneously inhibits a signal transduction pathway known as an immune evasion mechanism, and thus may be provided for the prevention or treatment of cancer.

Abstract: An electrode rolling apparatus including a non-coating portion pressing part for rolling a non-coating portion of an electrode substrate and an electrode rolling method using the same, making it is possible to prevent a swell from occurring in the non-coating portion region in the process of rolling the electrode substrate and enhance the manufacturing process efficiency.

Abstract: The present disclosure according to at least one embodiment provides a network congestion control method performed by a computing device, the method comprising transmitting data in units of packets to a receiving terminal connected to a network by performing a first step of increasing a data transmission amount for the data by increasing a window size; and performing a second step of reducing the data transmission amount by reducing the window size in response to an increase in round trip time (RTT) exceeding a predefined threshold value.

Abstract: An electrode manufacturing device is provided. The electrode manufacturing device includes a pressing roll configured to apply pressure to an uncoated part of the electrode, wherein the pressing roll comprises a central part, a first end part and a second end part, wherein the uncoated part comprises an insulating coated part and a non-insulating coated part, wherein the first end part is adjacent to a boundary between the insulating coated part and the non-insulating coated part, wherein the second end part is located at a portion far away from the insulating coated part, and wherein a first outer diameter of the central part connected to the first end part is greater than a second outer diameter of the central part connected to the second end part.

Abstract: In a vehicle seat for one-touch switching to a relaxation mode, a lever link operating in conjunction with a relaxation lever when a relaxation lever is raised up, or a relaxation lever bracket operating in conjunction with a motor cable of an actuator when a relaxation button lever is pushed down locks off a stepless brake. Thus, a rack bar is moved along a link tracking path. As a result, an angle of a cushion frame is changed in the upward direction, and a relaxation cable operated in conjunction with the relaxation lever link or a relaxation memory locks off the relaxation memory. In the present manner, a seat back is moved backward, enabling one-touch relaxation mechanism.

Abstract: The present invention relates to a hepatitis A virus production method and hepatitis A virus produced according to the method, and, more specifically, to: a hepatitis A virus production method and hepatitis A virus produced according to the method, the method comprising the step of infecting a host cell with a virus obtained by transforming a host cell with a vector comprising an expression cassette, which comprises a hepatitis A virus gene, for hepatitis A virus preparation, and subculturing same.

Abstract: A display device capable of improving a light emission efficiency includes a plurality of insulating films disposed on a substrate, a trench exposing side surfaces of the plurality of insulating films, a first alignment electrode disposed on the side surfaces of the plurality of insulating films exposed by the trench, a second alignment electrode disposed so as to be surrounded by the first alignment electrode, and a light-emitting device connected to the first and second alignment electrodes and disposed between the first and second alignment electrodes within the trench, thereby improving a light emission efficiency.

Abstract: A display device includes first and second alignment electrodes disposed on a substrate, an alignment insulating film having a concave portion disposed between the first and second alignment electrodes, a light-emitting device disposed on the alignment insulating film, first and second electrodes electrically connected to the light-emitting device, a thin-film transistor connected to one of the first and second electrodes, and a plurality of insulating films providing a trench disposed on the concave portion, the trench having a larger width than the concave portion, thereby improving emission efficiency.

Abstract: The present invention relates to a brain-metastatic lung cancer cell line and a use of Noggin as a marker for brain metastasis of lung cancer. In the present invention, a brain metastatic lung cancer cell line with optimized characteristics for brain metastasis was established by repeatedly transplanting the lung cancer cell line through the carotid artery. In addition, in the brain metastatic lung cancer cell line, the expressions of Noggin protein and its mRNA are reduced, confirming that the motility and invasiveness of cells are reduced and adhesion increased. Therefore, the Noggin protein or its gene is expected to be useful as a biomarker for diagnosis of brain metastasis of lung cancer and its target therapy.

Abstract: A display device having a reduced bezel area is discussed. The display device can include a base substrate having a first area and a second area disposed outside the first area and being bent, a first driving transistor part disposed on the first area of the base substrate, a first light emitting element connected to the first driving transistor part in the first area, at least one first trench part formed by being recessed in the second area of the base substrate, a second driving transistor part disposed in the at least one first trench part, and a second light emitting element connected to the second driving transistor part in the second area. As such, the display device is configured to emit light even in the second area which is bent at the edge of the display panel.

Abstract: The present disclosure relates to the detection of beta amyloid protein as an Alzheimer's disease-causing factor in the palatine tonsil and a use thereof and, more specifically, to the diagnosis of Alzheimer's disease by identifying the expression of beta amyloid and/or Staphylococcus aureus in a tonsillar sample. The present disclosure can diagnose Alzheimer's disease through the expression of beta amyloid and/or Staphylococcus aureus in a palatine tonsil tissue and, furthermore, can be very advantageously used for revealing the pathogenesis of Alzheimer's disease and for treating Alzheimer's disease.

Abstract: A magnetic coupling device according to an embodiment of the present invention includes a first bobbin including an upper surface, a lower surface, and an outer surface, a groove portion which is disposed on the inner side of the outer surface and is concave from the upper surface toward the lower surface, and a first terminal portion and a second terminal portion which are disposed on the outer surface and spaced apart from each other; a second bobbin disposed on the groove portion and accommodating a magnetic substance core; and a first coil and a second coil which are wound on the second bobbin and spaced apart from each other, wherein the first coil includes a first winding portion and a first extension portion, and the second coil includes a second winding portion, and a second extension portion.

Abstract: The present invention relates to a bobbin that can be used for a slim magnetic component. A bobbin for a magnetic part, according to one embodiment of the present invention, comprises: a first bobbin which has a space for accommodating a magnetic core therein, and which includes a pair of isolation protrusions disposed to be opposite to each other, so as to separate a first region and a second region; and a second bobbin including a coil-loading groove in which a first coil and a second coil are loaded while wound around the first bobbin, and terminals formed on the outside of the coil-loading groove in respective quadrant regions with respect to the coil-loading groove.

Abstract: A bispecific molecule according to an embodiment includes a B7-H3 antibody or an antigen-binding fragment thereof, and a transforming growth factor beta (TGF?) binding portion bound thereto. The bispecific molecule is bispecifically bound to B7-H3 and TGF? and thus can be utilized as an immune checkpoint inhibitor for various diseases including cancer.

Abstract: The present disclosure according to at least one embodiment provides a network congestion control method performed by a computing device, the method comprising transmitting data in units of packets to a receiving terminal connected to a network by performing a first step of increasing a data transmission amount for the data by increasing a window size; and performing a second step of reducing the data transmission amount by reducing the window size in response to an increase in round trip time (RTT) exceeding a predefined threshold value.

Abstract: A display apparatus includes a light-emitting device and an optical lens are stacked on an emission area of a device substrate. A black matrix and a touch electrode may be disposed on a non-emission area of the device substrate. An encapsulation unit covering the light-emitting device and an optical insulating layer covering the black matrix may be disposed on the emission area and the non-emission area of the device substrate. The touch electrode and the optical lens may be disposed on the optical insulating layer. A lens barrier may be disposed on the optical insulating layer. The optical lens may be surrounded by the lens barrier. Thus, in the display apparatus, a deform of the optical lens due to a reflow process may be prevented. Therefore, in the display apparatus, decreasing the quality of the image due to a process of forming the optical lens may be prevented.

Abstract: A display apparatus includes a light-emitting device and an optical lens are stacked on an emission area of a device substrate. A black matrix and a touch electrode may be disposed on a non-emission area of the device substrate. An encapsulation unit covering the light-emitting device and an optical insulating layer covering the black matrix may be disposed on the emission area and the non-emission area of the device substrate. The touch electrode and the optical lens may be disposed on the optical insulating layer. A lens barrier may be disposed on the optical insulating layer. The optical lens may be surrounded by the lens barrier. Thus, in the display apparatus, a deform of the optical lens due to a reflow process may be prevented. Therefore, in the display apparatus, decreasing the quality of the image due to a process of forming the optical lens may be prevented.

Abstract: An embodiment method of recognizing a parking floor for a vehicle includes recognizing a spot at which the vehicle enters a parking deck, obtaining an inclination signal indicating an inclination trajectory of the vehicle traveling during a parking period from entry to the parking deck to parking, obtaining an inclination pulse of the inclination signal based on a reference inclination value, and determining a floor number of the parking deck on which the vehicle is parked using the inclination pulse.

Abstract: A B7-H3 antibody or antigen-binding fragment thereof includes a heavy chain variable region including heavy chain complementarity determining regions (HCDRs) and a light chain variable region including light chain complementarity determining regions (LCDRs). The B7-H3 antibody has a predetermined complementarity determining region, thereby specifically binding to a B7-H3 antigen, and being internalized into cells, and being usable as an immune checkpoint inhibitor for various diseases.

Abstract: The present invention relates to a novel indole derivative and a use thereof. The novel indole derivative according to the present invention traps methylglyoxal (MGO), which is a main precursor of advanced glycation end products, and thus can be effectively used for preventing, improving, or treating diseases related to advanced glycation end products.