Abstract: Provided is a secondary battery pouch film, comprising an outer layer, a metal layer, and a sealant layer, wherein the sealant layer comprises a cast polypropylene (CPP) layer without an extruded polypropylene (PP) layer or comprises the cast polypropylene (CPP) layer and the extruded polypropylene (PP) layer, and the secondary battery pouch film satisfies specific equations. The pouch film has excellent formability, curling, insulation, bending, and peel strength.

Abstract: An embodiment multi-way coolant valve includes an outer housing including first to third outer inlets, first to third outer outlets, and a pump mount portion coupled to one of the outer outlets, an inner housing rotatably provided within the outer housing and including penetration holes corresponding to the outer inlets and outlets, a coolant line defined by a selective connection of the penetration holes such that the outer inlets and outlets are selectively connected, pads interposed between an interior circumference of the outer housing and an exterior circumference of the inner housing at locations of the outer inlets and outlets, respectively, and a driving device connected to a rotation center of the inner housing to selectively rotate the inner housing within the outer housing, wherein the inner housing is configured to rotate by a preset interval according to a selected vehicle mode.

Abstract: An apparatus and method for processing a substrate can reduce the concentration of process by-products in a chemical solution.

Abstract: A vehicle air conditioner for minimizing the leakage of air through a dual blocking structure between upper and lower flow paths, and having a dual blocking structure. An air-conditioning case having an inner air flow path is divided into an upper flow path and a lower flow path. A heat exchanger for cooling and a heat exchanger for heating are provided in the air flow path of the air-conditioning case. A member having through-holes is disposed downstream of the heat exchanger for heating in the flow direction of air and allows the air that has passed through the heat exchanger for heating to pass therethrough. The member having through-holes has a horizontal member dividing the upper flow path from the lower flow path. A leakage-preventing means is overlapped with the horizontal member so as to prevent the air in the upper flow path and the lower flow path from mixing.

Abstract: The present invention relates to a multi-conjugate of small interfering RNA (siRNA) and a preparing method of the same, more precisely a multi-conjugate of siRNA prepared by direct binding of double stranded sense/antisense siRNA monomers or indirect covalent bonding mediated by a cross-linking agent or a polymer, and a preparing method of the same. The preparing method of a siRNA multi-conjugate of the present invention is characterized by simple and efficient reaction and thereby the prepared siRNA multi-conjugate of the present invention has high molecular weight multiple times the conventional siRNA, so that it has high negative charge density, suggesting that it has excellent ionic interaction with a cationic gene carrier and high gene delivery efficiency.

Abstract: Embodiments provide a quantum dot that includes a core including zinc (Zn), tin (Sn) and phosphorus (P), and a shell surrounding the core, wherein a molar ratio of a number of moles of zinc to a number of moles of tin is in a range of about 0.1 to about 2. The quantum dots have high luminous efficiency and color purity.

Abstract: The present invention relates to antibody-drug conjugates (ADCs) wherein a plurality of active agents are conjugated to an antibody through at least one branched linker. The branched linker may comprise a branching unit, and two active agents are coupled to the branching unit through a secondary linker and the branching unit is coupled to the antibody by a primary linker. The active agents may be the same or different. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g., 2-4 branched linkers, which may each be coupled to a different C-terminal cysteine of a heavy or light chain of the antibody. The branched linker may comprise one active agent coupled to the branching unit by a first branch and a second branch that comprises a polyethylene glycol moiety coupled to the branching unit. In certain such embodiments, two or more such branched linkers are conjugated to the antibody, e.g.

Abstract: The present disclosure relates to a method for producing a nonwoven fabric that improves filtration performance when applied as a filter material. By adjusting the modification ratio of the Y-shaped cross-section of polyester filaments constituting the nonwoven fabric, when applied to a filter by increasing a specific surface area of the nonwoven fabric, it increases the collection amount of the materials to be filtered and maintains a low differential pressure, thus enabling long-term use.

Abstract: The present invention relates to a pharmaceutical composition, for treating glioblastoma, comprising a nucleic acid complex as an active ingredient and, more particularly, to a pharmaceutical composition, for preventing or treating glioblastoma, comprising a nucleic acid complex having complementarily bound: a bioactive peptide nucleic acid having a sequence binding to TGF-?2 gene; and a carrier peptide nucleic acid. The nucleic acid complex according to the present invention has excellent cell permeability and intracellular activity and can effectively inhibit the expression of TGF-?2 gene and the hypostatic gene thereof, and thus is useful in preventing or treating glioblastoma.

Abstract: The present invention relates to a novel naphthyridinone derivative compound, a pharmaceutically acceptable salt thereof, a hydrate thereof, or a stereoisomer thereof, which are each relevant to a compound for inhibiting ENPP1, a composition for inhibiting ENPP1, and a method for inhibiting ENPP1.

Abstract: A water purifier is provided. A water purifier according to one aspect of the present invention may include a housing having a first accommodation space therein, and made of a paper material; a water purifier faucet disposed in the first accommodation space to receive raw water and discharge purified water; and a filter coupled to the water purifier faucet to generate the purified water by filtering the raw water, wherein the water purifier faucet includes a base frame having a second accommodation space therein in which the filter is accommodated; a water inlet module provided on one side of the base frame to supply raw water introduced from the outside to the filter; and a water outlet module provided on the other side of the base frame to receive the purified water generated by the filter and discharge it to the outside.

Abstract: A display device includes a display panel which operates in a sensing mode or an emission mode, and a data driver electrically connected to the display panel. The display panel includes a first pixel, a second pixel, a third pixel, a fourth pixel, a fifth pixel, a sixth pixel, a first scan line, a second scan line, a first data line, the second pixel. The data driver includes a first switch, a second switch, and an analog front end. The sensing mode includes a first period in which a first scan signal is provided to the first scan line and the first switch is turned on, a second period in which the first scan signal is provided to the first scan line and the second switch is turned on, and a third period in which a second scan signal is provided to the second scan line.

Abstract: Disclosed is a secondary battery pouch film, including an outer layer, a metal layer, and a sealant layer, wherein the sealant layer includes a cast polypropylene (CPP) layer and an extruded polypropylene (PP) layer, and the secondary battery pouch film satisfies the [Equation 1] where A+B<1.354, 0.6?C. In [Equation 1], A is a value obtained by dividing a thickness of the metal layer by a total thickness of the secondary battery pouch film, B is a value obtained by dividing a thickness of the metal layer by a thickness of the sealant layer, and C is a value obtained by dividing a thickness of the extruded polypropylene (PP) layer of the sealant layer by a thickness of the cast polypropylene (CPP) layer of the sealant layer. The pouch film has excellent formability, curling, insulation, bending, and peel strength.

Abstract: The present invention relates to a composition for preventing or treating transplantation rejection or a transplantation rejection disease, comprising a novel compound and a calcineurin inhibitor. A co-administration of the present invention 1) reduces the activity of pathogenic Th1 cells or Th17 cells, 2) increases the activity of Treg cells, 3) has an inhibitory effect against side effects, such as tissue damage, occurring in the sole administration thereof, 4) inhibits various pathogenic pathways, 5) inhibits the cell death of inflammatory cells, and 6) increases the activity of mitochondria, in an in vivo or in vitro allogenic model, a transplantation rejection disease model, a skin transplantation model, and a liver-transplanted patient, and thus inhibits transplantation rejection along with mitigating side effects possibly occurring in the administration of a conventional immunosuppressant alone.

Abstract: Disclosed are a white organic light emitting element, which may uniformize the color coordinates of white regardless of a change in current density by changing the configuration of different kinds of light emitting layers contacting each other, and a display device using the same.

Abstract: Provided a liquid crystal composition including ceramide, a method of preparing the same, and a cosmetic composition including the same. According to a liquid crystal composition including various types of ceramide of an aspect and a method of preparing the same, the liquid crystal composition not only has high liquid crystal stability that liquid crystal is maintained even after 4 weeks at a high temperature, but also activities of increasing an amount of ceramide, increasing an expression level of aquaporin 3, increasing an amount of filaggrin, increasing an expression level of hyaluronic acid, increasing an expression level of loricrin, increasing an expression level of involucrin, and increasing a thickness of the skin, resulting in effects usefully available for amelioration of the skin conditions.

Abstract: A positive electrode active material for a lithium secondary battery, a manufacturing method thereof, and it is provided a positive electrode active material for a lithium secondary battery, comprising: a core containing a lithium nickel-based compound having a Ni content of 80 mol % or more; and a coating material positioned on at least a portion of the core surface; wherein, the coating material includes a first coating material containing at least one of group 5 elements and group 6 elements; and S; and a second coating material including B, LiOH, Li2CO3 and Li2SO4.

Abstract: Methods of making orally available softgels includes pre-wetting a probiotic with an edible oil to produce a wetted supplement, wherein the edible oil is present in a range of 25% to 75% by weight of a total weight of the probiotic and edible oil, heating the wetted supplement to a temperature in a range of 35° C. to 40° C., blending the wetted supplement and a molten chocolate component together to produce a liquid fill material, encapsulating the liquid fill material in a softgel coating to produce an orally available softgel, and cooling the orally available softgel to have a softgel capsule shell comprising 5% to 15% by weight water. The fill material is a solid at room temperature in the cooled orally available softgel.

Abstract: Provided is a compound of Chemical Formula 1 or 2: wherein: R1 to R4 are each independently hydrogen or deuterium; n1 to n4 are an integer of 1 to 4; L1 and L2 are each independently a direct bond or a substituted or unsubstituted C6-60 arylene; and Ar1 and Ar2 are each independently a substituent of Chemical Formula 3: wherein X1 to X5 are each independently N or C(R5), wherein at least two of X1 to X5 are N; and each R5 is independently hydrogen, deuterium, a substituted or unsubstituted C1-20 alkyl, a substituted or unsubstituted C6-60 aryl, or a substituted or unsubstituted C2-60 heteroaryl containing at least one of N, O and S, or two adjacent R5s combine to form a benzene ring; and an organic light emitting device including the same. The device exhibits significantly superior efficiency and lifespan.

Abstract: Disclosed is a method of removing lead materials from an anode for manufacturing copper foil to regenerate the anode. The method includes cleaning solution preparation, anode cleaning and anode washing. The cleaning solution preparation includes preparing a cleaning solution containing an aqueous solution of EDTA and citric acid. The cleaning solution used to perform the anode cleaning has a pH of 7 to 9 and a temperature of 20 to 50° C. The anode cleaning includes cleaning the anode by immersing the anode including the lead materials attached to the surface thereof in the cleaning solution to perform EDTA-Pb chelation. As a result, the transfer of the lead materials from the anode to the cleaning solution means substantial removal of the lead materials from the anode. The anode, from which the lead materials have been removed, is washed using a high-pressure washer.