Abstract: A cigarette includes a tobacco rod, a front end plug positioned at a front end of the tobacco rod, a filter rod positioned at a rear end of the tobacco rod, and a wrapper surrounding the tobacco rod, the front end plug, and the filter rod and including at least one perforation formed in an area of the wrapper to allow air to flow to the inside of the wrapper.

Abstract: Provided is an aerosol-generating article including a wrapper which is discolored as the aerosol-generating material is heated, the aerosol-generating article including: a tobacco rod; a front-end plug arranged on a side of the tobacco rod; a filter rod arranged on the other side of the tobacco rod; and the wrapper surrounding the tobacco rod, the front-end plug, and the filter rod, wherein the wrapper includes a thermochromic material which is heated and discolored by an aerosol-generating device when the aerosol-generating article is inserted into the aerosol-generating device.

Abstract: The present invention relates to a composition for enhancing a survival rate of stem cells, including an immunosuppressant, and to a use thereof. According to the present invention, a survival rate of stem cells can be remarkably enhanced using a composition including an immunosuppressant, and a therapeutic effect of stem cells can be improved on the basis of the enhancement. The composition can overcome an immune response caused by the administration of xenogeneic cells so as to accurately verify the stability and efficacy of cells, and thus will be able to be utilized as a mesenchymal stem cell therapeutic agent that maximizes a therapeutic effect of stem cells.

Abstract: The present invention relates to a modified TXNIP protein, a method for preparing the modified TXNIP protein, a polynucleotide encoding the modified protein, an expression vector including the polynucleotide, a transformant introduced with the expression vector, a method for crystallizing a modified TRX-TXNIP complex using the modified TXNIP protein, and a method for screening a substance regulating interaction between TRX and TXNIP, an inhibitor of TRX activity, or a substance regulating TXNIP function.

Abstract: The present invention relates to a three-dimensional structure of a complex explored by crystallization of the complex of NanR which is a key pathogenic regulatory protein of Vibrio vulnificus and ManNA6P which is a NanR regulator. Further, the present invention relates to a modified NanR protein, a polynucleotide encoding the protein, a vector including the polynucleotide, and a transformant including the vector. Furthermore, the present invention relates to a method for screening a substance regulating interaction between NanR and the transcriptional control region of nan operon which is a gene cluster regulated by NanR, or a substance regulating interaction between NanR and ManNAc-6P, by designing three-dimensional structure of the complex, and to an antibacterial composition including the screened substance.

Abstract: The present invention relates to a modified TXNIP protein, a method for preparing the modified TXNIP protein, a polynucleotide encoding the modified protein, an expression vector including the polynucleotide, a transformant introduced with the expression vector, a method for crystallizing a modified TRX-TXNIP complex using the modified TXNIP protein, and a method for screening a substance regulating interaction between TRX and TXNIP, an inhibitor of TRX activity, or a substance regulating TXNIP function.

Abstract: The present invention relates to a three-dimensional structure of a complex explored by crystallization of the complex of NanR which is a key pathogenic regulatory protein of Vibrio vulnificus and ManNA6P which is a NanR regulator. Further, the present invention relates to a modified NanR protein, a polynucleotide encoding the protein, a vector including the polynucleotide, and a transformant including the vector. Furthermore, the present invention relates to a method for screening a substance regulating interaction between NanR and the transcriptional control region of nan operon which is a gene cluster regulated by NanR, or a substance regulating interaction between NanR and ManNAc-6P, by designing three-dimensional structure of the complex, and to an antibacterial composition including the screened substance.

Abstract: Two vIRF4 (Kaposi's-sarcoma-associated-herpesvirus vIRF4) peptides, vif1, corresponding to aa202-216 of vIRF4, and vif2, corresponding to aa220-236 of vIRF4, are potent and selective HAUSP antagonists. The vif1 and vif2 peptides robustly suppress HAUSP DUB enzymatic activity, ultimately leading to p53-mediated anti-cancer activity. The vif1 and vif2 peptides, along with their homologues, are useful in treating cancer through regulation of p53 activity in a cancer cell. Also disclosed is the crystalline structure of vIRF4-HAUSP TRAF domain complex. The structure is useful in computer aided drug design for identifying an agent that interacts with and inhibits HAUSP, resulting in p53 medicated cell cycle arrest of cancer cells.

Abstract: A backlight assembly includes a switching section for switching on/off an input voltage so as to output a primary voltage in accordance with a control signal; and a voltage boosting section for boosting the primary voltage received at a primary side thereof to a secondary voltage at a secondary side thereof. The primary and secondary sides of the voltage boosting section are electrically isolated from each other. In a feedback link for supplying the control signal from the secondary side to the primary side, a signal isolation section is provided for both transmitting the control signal between and electrically isolating primary side and secondary side portions of the feedback link. Additionally or alternatively, a balancing circuit section is connected between the secondary side of the voltage boosting section and a plurality of lamps so as to uniformly supply an alternating current, generated by the secondary voltage, to the lamps, in order to uniformize the luminances of the lamps.

Abstract: Disclosed herein is a backlight inverter for a U-shaped lamp which is capable of detecting an abnormal state of an inverter circuit. The backlight inverter comprises a driver for supplying first and second transformer drive voltages in response to an operation control signal and cutting off the supply of the transformer drive voltages in response to a shutdown control signal, first and second transformers for boosting the transformer drive voltage in a turn ratio between primary and secondary windings thereof and supplying the resulting drive voltage to the U-shaped lamp, first and second voltage detectors for detecting voltages across the secondary windings, respectively, first and second current detectors for detecting currents flowing through the secondary windings of the first and second transformers, respectively, an inverter abnormal state detector for detecting an abnormal state of the inverter, and a driver controller for controlling a normal operation or shutdown of the driver.