Abstract: A method for calibrating a spatial pose and position of a chromatic confocal probe with combined planar and spherical constraints is provided. The method includes: transforming point information in a contact probe coordinate system into coordinate information in a machine coordinate system, and transforming point information in a chromatic confocal probe coordinate system into the coordinate information in the machine coordinate system; acquiring information of at least two points in each of three planes by using a chromatic confocal probe, and establishing a system of linear equations to solving the system of linear equations to obtain a spatial pose of the chromatic confocal probe; measuring and calculating coordinate information of at least three points on a spherical surface by using the chromatic confocal probe, and establishing an overdetermined system of equations to solve a zero reference position of the chromatic confocal probe.