Abstract: According to the present invention, there are provided inhibitors against prostate-specific antigen which comprise as a minimum unit a peptide consisting of Gly-Phe-Tyr-Lys-Lys-Lys-Gln-Ser-Arg, and such inhibitors can be expected to constitute a therapeutic drug against prostate carcinoma and prostate hyperplasia.

Abstract: The present invention permits human urinary thrombomodulin to be purified by a simple and practical procedure, while it enables even a starting material with a lowered content of thrombomodulin to be purified by greater purification rate than the one with a high content of thrombomodulin.

Abstract: A remitting agent for nephrotic syndrome and hepatopathy symptoms is provided that which comprises water-soluble polysaccharides having poly-D-galacturonic acid as an effective constituent; polysaccharides having the following characteristic properties which are extractable from Tanjin with water or an aqueous solvent:A. Sugar content: 60 to 100%.(1) Sugar composition:40 to 80% of uronic acid (composed almost entirely of D-galacturonic acid) and10 to 30% of neutral sugars(2) Neutral sugar composition:0 to 15% of rhamnose0 to 15% of glucose25 to 55% of galactose30 to 60% of arabinose0 to 15% of mannoseB. Molecular weight: 150,000 to 300,000; the invention also provides a process for producing the above-described polysaccharides which comprises allowing an aqueous extract of Tanjin to pass through a porous polymeric resin, followed by purification through gel filtration chromatography.