Abstract: Provided herein are methods of analyzing tissue using a magnetic resonance imaging (MRI) compatible tissue analysis device that includes radio¬frequency (RF) tracking and imaging elements. Related kits, systems, and computer program products are also provided.

Abstract: A computing device having a first processor configured to receive three-dimensional imaging data acquired by an imaging system, the three-dimensional imaging data being from ahead of a subject. The first processor can be configured to determine vascular structures from the three-dimensional imaging data, generate a three-dimensional model of the head of the subject from the three-dimensional imaging data, the three-dimensional model of the head including a three-dimensional model of the vascular structures and a three-dimensional model of a portion of a frontal horn of the subject, determine an entry point on the three-dimensional model of the head of the subject, determine a plurality of trajectories, each trajectory intersecting the three-dimensional model of the portion of the frontal horn and does not intersect the three-dimensional model of the vascular structures, and each trajectory is linear, and select a final trajectory from the plurality of trajectories.

Abstract: Exemplary methods, apparatus, and systems are disclosed for automated registration and motion compensation of patient-mounted needle guide medical devices using fiducial markers, and processing algorithms where a re-registration step is provided. These methods, apparati, and systems adaptively compensate for the displacement of the medical device and/or target location due to the patient movement or internal organ motion.

Abstract: The present disclosure is directed to systems and methods for generating images using short tau inversion recovery, ultrashort echo time (STIR-UTE) MRI sequences. The STIR-UTE MRI sequences can be used to generate images that can differentiate between regions that are at temperatures that are either lethal or non-lethal to cell life. Thus, these sequences can be beneficial for implementations such as in monitoring cryoablation procedures.

Abstract: Exemplary methods, apparatus, and systems are provided for automated detection and registration of medical images using fiducial markers and processing algorithms. By either clustering fiducial markers having a different number, size, shape, configuration, or material property or by using fiducial markers arranged in a ring shape, wherein their arrangement is asymmetric, and then applying a feature extraction to extract the fiducial marker objects, and registering the fiducial marker objects with a model of the fiducial frame, automatic registration can be achieved.

Abstract: A positioning apparatus including a needle holder having a through hole for regulating needle placement and movement, a needle positioning unit, and an engagement member that fixes a position of the needle holder with respect to the needle positioning unit. The needle holder is either least partially detachably attached to the needle positioning unit or deformable. The positioning apparatus may be designed to accommodate the placement of multiple needles.

Abstract: A needle placement manipulator includes, a needle holder configured to hold a needle, a guide system configured to position the needle holder to a predetermined direction with respect to a subject of needle placement, an attachment including an attaching portion to which the guide system is attached and a setting portion on which an RF-coil is set. A base surface of the setting portion is configured to be disposed on the subject.

Abstract: A method and system for motion tracking of a target organ are provided. A tracking needle is partially inserted into an organ. The needle has a sensor element for obtaining continuous needle orientation information which can be used to determine organ motion due to respiration during percutaneous needle insertion.

Abstract: Exemplary methods, apparatus, and systems are disclosed for automated registration and motion compensation of patient-mounted needle guide medical devices using fiducial markers, and processing algorithms where a re-registration step is provided. These methods, apparati, and systems adaptively compensate for the displacement of the medical device and/or target location due to the patient movement or internal organ motion.

Abstract: A system and method for automatic registration of medical images includes accessing image data of a subject and plurality of elongated fiducial markers arranged in an asymmetrical orientation and analyzing the image data to detect the elongated fiducial markers by applying a line filter to treat the elongated fiducial markers as lines within the image data. The system and method also includes matching the elongated fiducial markers within the image data to a model of the elongated fiducial markers, registering the image data with a coordinate system based on the matching, and generating a report indicating at least the registered image data.

Abstract: Exemplary methods, apparatus, and systems are provided for automated detection and registration of medical images using fiducial markers and processing algorithms. By either clustering fiducial markers having a different number, size, shape, configuration, or material property or by using fiducial markers arranged in a ring shape, wherein their arrangement is asymmetric, and then applying a feature extraction to extract the fiducial marker objects, and registering the fiducial marker objects with a model of the fiducial frame, automatic registration can be achieved.

Abstract: A system and method for modifying an imaging plane of a medical imaging device is presented. An electronic device includes a tilt sensor. The electronic device is configured to monitor a tilt of the electronic device. A computer is configured to receive an indication of the tilt of the electronic device, translate the indication of the tilt of the electronic device into a corresponding movement of the imaging plane of the medical imaging device, and transmit an instruction to the medical imaging device to cause the corresponding movement of the imaging plane. The medical imaging device may include an magnetic resonance imaging (MRI) system.

Abstract: A positioning apparatus including a needle holder having a through hole for regulating needle placement and movement, a needle positioning unit, and an engagement member that fixes a position of the needle holder with respect to the needle positioning unit. The needle holder is either least partially detachably attached to the needle positioning unit or deformable. The positioning apparatus may be designed to accommodate the placement of multiple needles.

Abstract: A needle placement manipulator includes, a pair of rotary guides arranged at a slanted angle with respect to each other, a needle holder which holds a needle along a needle holder axis, and a base body on which the guides are supported. The needle holder axis and each axis of the rotary guides cross at a single point located at or below the base body. The base body is configured to be attached to a patient or to an RF-coil.

Abstract: A system and method for automatic registration of medical images includes accessing image data of a subject and plurality of elongated fiducial markers arranged in an asymmetrical orientation and analyzing the image data to detect the elongated fiducial markers by applying a line filter to treat the elongated fiducial markers as lines within the image data. The system and method also includes matching the elongated fiducial markers within the image data to a model of the elongated fiducial markers, registering the image data with a coordinate system based on the matching, and generating a report indicating at least the registered image data.

Abstract: A needle placement manipulator includes, a pair of rotary guides arranged at a slanted angle with respect to each other, a needle holder which holds a needle along a needle holder axis, and a base body on which the guides are supported. The needle holder axis and each axis of the rotary guides cross at a single point located at or below the base body. The base body is configured to be attached to a patient or to an RF-coil.

Abstract: A needle placement manipulator includes, a needle holder configured to hold a needle, a guide system configured to position the needle holder to a predetermined direction with respect to a subject of needle placement, an attachment including an attaching portion to which the guide system is attached and a setting portion on which an RF-coil is set. A base surface of the setting portion is configured to be disposed on the subject.

Abstract: A system and method for modifying an imaging plane of a medical imaging device is presented. An electronic device includes a tilt sensor. The electronic device is configured to monitor a tilt of the electronic device. A computer is configured to receive an indication of the tilt of the electronic device, translate the indication of the tilt of the electronic device into a corresponding movement of the imaging plane of the medical imaging device, and transmit an instruction to the medical imaging device to cause the corresponding movement of the imaging plane. The medical imaging device may include an magnetic resonance imaging (MRI) system.