Patents by Inventor Junichiro SONODA

Junichiro SONODA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FGFR1 AGONISTS AND METHODS OF USE
    Publication number: 20240076388
    Abstract: The invention provides FGFR1 agonists, including agonistic anti-FGFR1 antibodies, and methods of using the same.
    Type: Application
    Filed: April 3, 2023
    Publication date: March 7, 2024
    Applicant: GENENTECH, INC.
    Inventors: Junichiro Sonoda, Yan Wu
  • ANTIBODIES AND METHODS OF USE
    Publication number: 20240026033
    Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
    Type: Application
    Filed: March 31, 2023
    Publication date: January 25, 2024
    Applicant: Genentech, Inc.
    Inventors: Yongmei Chen, James Ernst, Hok Seon Kim, Junichiro Sonoda, Christoph Spiess, Scott Stawicki, Yan Wu
  • ANTIBODIES AND METHODS OF USE
    Publication number: 20220064331
    Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
    Type: Application
    Filed: June 8, 2021
    Publication date: March 3, 2022
    Applicant: GENENTECH, INC.
    Inventors: Yongmei Chen, James Ernst, Hok Seon Kim, Junichiro Sonoda, Christoph Spiess, Scott Stawicki, Yan Wu
  • FGFR1 AGONISTS AND METHODS OF USE
    Publication number: 20210087283
    Abstract: The invention provides FGFR1 agonists, including agonistic anti-FGFR1 antibodies, and methods of using the same.
    Type: Application
    Filed: October 19, 2020
    Publication date: March 25, 2021
    Applicant: Genentech, Inc.
    Inventors: Junichiro Sonoda, Yan Wu
  • METHODS FOR DETECTING AND QUANTIFYING FGF21
    Publication number: 20210025890
    Abstract: The presently disclosed subject matter provides antibodies that bind FGF21 and methods of using the same. In particular, the present disclosure provides immunoassay methods for detecting and quantifying active and total FGF21 levels in a sample and kits for performing such methods.
    Type: Application
    Filed: October 5, 2020
    Publication date: January 28, 2021
    Applicant: GENENTECH, INC.
    Inventors: John Hok Nin Lowe, Junichiro Sonoda
  • Host cell comprising nucleic acids encoding bispecific antibodies binding to beta-klotho and fibroblast growth factor receptor 1 and antibody production
    Patent number: 10882921
    Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
    Type: Grant
    Filed: February 25, 2019
    Date of Patent: January 5, 2021
    Assignee: GENENTECH, INC.
    Inventors: Yongmei Chen, James Ernst, Hok Seon Kim, Junichiro Sonoda, Christoph Spiess, Scott Stawicki, Yan Wu
  • FGFR1 AGONISTS AND METHODS OF USE
    Publication number: 20200140557
    Abstract: The invention provides FGFR1 agonists, including agonistic anti-FGFR1 antibodies, and methods of using the same.
    Type: Application
    Filed: May 16, 2019
    Publication date: May 7, 2020
    Applicant: Genentech, Inc.
    Inventors: Junichiro Sonoda, Yan Wu
  • SUBSTRATES RECOGNIZED BY FIBROBLAST ACTIVATION PROTEIN (FAP) AND METHODS OF USING THE SAME
    Publication number: 20200055896
    Abstract: Fluorescence resonance energy transfer (FRET) constructs comprising donor and acceptor fluorophore moieties, and a peptide linking the two, which is a substrate of the endopeptidase fibroblast activation protein (FAP). Also provided are isolated nucleic acids expressing the construct, cell lines comprising the nucleic acids, and kits comprising the construct. Further provided are methods of detecting FAP using the construct via FRET.
    Type: Application
    Filed: October 1, 2019
    Publication date: February 20, 2020
    Inventors: Travis William BAINBRIDGE, James Andrew ERNST, Junichiro SONODA
  • ANTIBODIES AND METHODS OF USE
    Publication number: 20190177432
    Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
    Type: Application
    Filed: February 25, 2019
    Publication date: June 13, 2019
    Applicant: GENENTECH, INC.
    Inventors: Yongmei Chen, James Ernst, Hok Seon Kim, Junichiro Sonoda, Christoph Spiess, Scott Stawicki, Yan Wu
  • Nucleic acids encoding bispecific antibodies binding to beta-Klotho and fibroblast growth factor receptor 1
    Patent number: 10246518
    Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
    Type: Grant
    Filed: December 11, 2017
    Date of Patent: April 2, 2019
    Assignee: Genentech, Inc.
    Inventors: Yongmei Chen, James Ernst, Hok Seon Kim, Junichiro Sonoda, Christoph Spiess, Scott Stawicki, Yan Wu
  • Anti-FGFR2/3 antibodies and methods using same
    Patent number: 10208120
    Abstract: The invention provides dual specific anti-FGFR2 and FGFR3 (FGFR2/3) antibodies, and compositions comprising and methods of using these antibodies.
    Type: Grant
    Filed: November 5, 2015
    Date of Patent: February 19, 2019
    Assignee: GENENTECH, INC.
    Inventors: Yiyuan Yin, Avi Ashkenazi, Paul J. Carter, Mark Chen, Junichiro Sonoda
  • METHODS OF SCREENING FOR MULTISPECIFIC ANTIBODIES
    Publication number: 20190040142
    Abstract: The presently disclosed subject matter relates to multispecific antibodies, e.g., bispecific antibodies and biepitopic antibodies, and methods for screening for such antibodies, and a novel antibody structure that can be used to screen for such bispecific antibodies and biepitopic antibodies.
    Type: Application
    Filed: May 8, 2018
    Publication date: February 7, 2019
    Applicant: GENENTECH, INC.
    Inventors: Diana Ronai Dunshee, Joanne Hongo, Hok Seon Kim, Junichiro Sonoda, Christoph Spiess, Angie Grace Yee
  • ANTIBODIES AND METHODS OF USE
    Publication number: 20180105605
    Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
    Type: Application
    Filed: December 11, 2017
    Publication date: April 19, 2018
    Inventors: Yongmei Chen, James Ernst, Hok Seon Kim, Junichiro Sonoda, Christoph Spiess, Scott Stawicki, Yan Wu
  • FGFR1 AGONISTS AND METHODS OF USE
    Publication number: 20180100018
    Abstract: The invention provides nucleic acid molecules encoding anti-fibroblast growth factor receptor-1 (FGFR1) antibodies and vectors and host cells comprising the nucleic acid molecules.
    Type: Application
    Filed: November 10, 2017
    Publication date: April 12, 2018
    Applicant: Genentech, Inc.
    Inventors: Junichiro Sonoda, Yan WU
  • CHIMERIC FIBROBLAST GROWTH FACTORS WITH ALTERED RECEPTOR SPECIFICITY
    Publication number: 20180079806
    Abstract: The present invention is directed to novel chimeric fibroblast growth factor (FGF) polypeptides, novel DNA encoding chimeric FGF polypeptides, and to the recombinant production of chimeric FGF polypeptides, and to methods, compositions and assays utilizing chimeric FGF polypeptides for the therapeutic treatment of metabolic-related disorders and other conditions, and for producing pharmaceutically active compositions including chimeric FGF polypeptides, the compositions having therapeutic and pharmacologic properties including those associated with the treatment of metabolic-related disorders and other conditions.
    Type: Application
    Filed: August 3, 2017
    Publication date: March 22, 2018
    Inventor: Junichiro SONODA
  • Methods of treatment with bispecific antibodies binding to beta-klotho and fibroblast growth factor receptor 1
    Patent number: 9884919
    Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: February 6, 2018
    Assignee: GENENTECH, INC.
    Inventors: Yongmei Chen, James Ernst, Hok Seon Kim, Junichiro Sonoda, Christoph Spiess, Scott Stawicki, Yan Wu
  • Bispecific antibodies binding to beta-klotho and fibroblast growth factor receptor 1
    Patent number: 9873748
    Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
    Type: Grant
    Filed: December 23, 2014
    Date of Patent: January 23, 2018
    Assignee: GENENTECH, INC.
    Inventors: Yongmei Chen, James Ernst, Hok Seon Kim, Junichiro Sonoda, Christoph Spiess, Scott Stawicki, Yan Wu
  • FGFR1 agonists and methods of use
    Patent number: 9845359
    Abstract: The invention provides FGFR1 agonists, including agonistic anti-FGFR1 antibodies, and methods of using the same.
    Type: Grant
    Filed: June 29, 2015
    Date of Patent: December 19, 2017
    Assignee: Genentech, Inc.
    Inventors: Junichiro Sonoda, Yan Wu
  • ANTIBODIES AND METHODS OF USE
    Publication number: 20160319038
    Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
    Type: Application
    Filed: July 19, 2016
    Publication date: November 3, 2016
    Applicant: GENENTECH, INC.
    Inventors: YONGMEI CHEN, James Ernst, Hok Seon Kim, Junichiro Sonoda, Christoph Spiess, Scott Stawicki, Yan Wu
  • ANTI-FGFR2/3 ANTIBODIES AND METHODS USING SAME
    Publication number: 20160244525
    Abstract: The invention provides dual specific anti-FGFR2 and FGFR3 (FGFR2/3) antibodies, and compositions comprising and methods of using these antibodies.
    Type: Application
    Filed: November 5, 2015
    Publication date: August 25, 2016
    Applicant: GENENTECH, INC.
    Inventors: Yiyuan YIN, Avi ASHKENAZI, Paul J. CARTER, Mark CHEN, Junichiro SONODA