Patents by Inventor Junji Uchida
Junji Uchida has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 9814724Abstract: The present invention provides an antitumor effect potentiator for enhancing antitumor activity of an antitumor agent comprising tegafur in a therapeutically effective amount, gimeracil in an amount effective for enhancing an antitumor effect, and oteracil potassium in an amount effective for inhibiting a side effect. The antitumor effect potentiator comprising at least one member selected from the group consisting of folinic acid and pharmacologically acceptable salts thereof. The present invention also provides a method for enhancing an antitumor effect of an antitumor agent comprising the step of administering to a patient the aforementioned antitumor effect potentiator; a method for inhibiting the growth of a tumor comprising the step of administering to a patient the aforementioned antitumor effect potentiator and a method for cancer treatment comprising the step of administering to a patient the aforementioned antitumor agent.Type: GrantFiled: February 17, 2017Date of Patent: November 14, 2017Assignee: Taiho Pharmaceutical Co., Ltd.Inventors: Junji Uchida, Koyo Shudo
-
Publication number: 20170157131Abstract: The present invention provides an antitumor effect potentiator for enhancing antitumor activity of an antitumor agent comprising tegafur in a therapeutically effective amount, gimeracil in an amount effective for enhancing an antitumor effect, and oteracil potassium in an amount effective for inhibiting a side effect. The antitumor effect potentiator comprising at least one member selected from the group consisting of folinic acid and pharmacologically acceptable salts thereof. The present invention also provides a method for enhancing an antitumor effect of an antitumor agent comprising the step of administering to a patient the aforementioned antitumor effect potentiator; a method for inhibiting the growth of a tumor comprising the step of administering to a patient the aforementioned antitumor effect potentiator and a method for cancer treatment comprising the step of administering to a patient the aforementioned antitumor agent.Type: ApplicationFiled: February 17, 2017Publication date: June 8, 2017Applicant: TAIHO PHARMACEUTICAL CO., LTD.Inventors: Junji UCHIDA, Koyo SHUDO
-
Patent number: 9611227Abstract: The present invention provides an antitumor effect potentiator for enhancing antitumor activity of an antitumor agent comprising tegafur in a therapeutically effective amount, gimeracil in an amount effective for enhancing an antitumor effect, and oteracil potassium in an amount effective for inhibiting a side effect. The antitumor effect potentiator comprising at least one member selected from the group consisting of folinic acid and pharmacologically acceptable salts thereof. The present invention also provides a method for enhancing an antitumor effect of an antitumor agent comprising the step of administering to a patient the aforementioned antitumor effect potentiator; and a method for cancer treatment comprising the step of administering to a patient the aforementioned antitumor agent.Type: GrantFiled: March 11, 2004Date of Patent: April 4, 2017Assignee: Taiho Pharmaceutical Co., Ltd.Inventors: Junji Uchida, Koyo Shudo
-
Publication number: 20170088625Abstract: The present invention provides monoclonal antibodies and antigen-binding fragments thereof that specifically bind to CD20, as well as pharmaceutical compositions comprising the same. The invention further provides methods of using the monoclonal antibodies, antigen-binding fragments, and pharmaceutical compositions, for example, in methods of depleting B cells or in treating B cell disorders. Also provided are cells, nucleic acids and methods for producing the monoclonal antibodies.Type: ApplicationFiled: July 13, 2016Publication date: March 30, 2017Inventors: Thomas F. Tedder, Junji Uchida, Yasuhito Hamaguchi, Jonathan C. Poe
-
Publication number: 20150110864Abstract: A primary object of the present invention is to provide a novel combination therapy that exhibits a notable antitumor effect. As means for achieving the object, an antitumor agent comprising a combination of oxaliplatin, paclitaxel, and a combination drug containing tegafur, gimeracil, and oteracil potassium is provided.Type: ApplicationFiled: March 15, 2013Publication date: April 23, 2015Applicant: Taiho Pharmaceutical Co., Ltd.Inventor: Junji Uchida
-
Publication number: 20140227706Abstract: The object of the invention is to provide a method for quantitatively assessing the degree of progression of a malignant neoplasm in a patient who has been medicated.Type: ApplicationFiled: May 16, 2012Publication date: August 14, 2014Applicants: DNA CHIP RESEARCH INC., Osaka Prefectural Hospital OrganizationInventors: Kikuya Kato, Fumio Imamura, Kazuya Taniguchi, Toru Kumagai, Junji Uchida, Kazumi Nishino
-
Publication number: 20090136516Abstract: The present invention provides monoclonal antibodies and antigen-binding fragments thereof that specifically bind to CD20, as well as pharmaceutical compositions comprising the same. The invention further provides methods of using the monoclonal antibodies, antigen-binding fragments, and pharmaceutical compositions, for example, in methods of depleting B cells or in treating B cell disorders. Also provided are cells, nucleic acids and methods for producing the monoclonal antibodies.Type: ApplicationFiled: May 7, 2004Publication date: May 28, 2009Inventors: Thomas F. Tedder, Junji Uchida, Yasuhito Hamaguchi, Jonathan C. Poe
-
Publication number: 20080306073Abstract: An antitumor effect fortifier comprising as an active ingredient an effective amount of platinum (II) cis-oxalato(1R,2R-diaminocyclohexane) so as to enhance the antitumor activity of antitumor agent containing a therapeutically effective amount of tegafur, an amount, effective for the enhancement of antitumor effect, of gimeracil and an amount, effective for the suppression of side effects, of oteracil potassium; and a relevant antitumor agent. Further, there is provided a method of therapy for cancer, characterized in that an amount, effective for the enhancement of antitumor effect, of platinum (II) cis-oxalato(1R,2R-diaminocyclohexane) is concomitantly administered to a mammal.Type: ApplicationFiled: June 2, 2005Publication date: December 11, 2008Inventors: Katsuhisa Koizumi, Junji Uchida, Teiji Takechi, Mamoru Nukatsuka
-
Publication number: 20060116345Abstract: The present invention provides an antitumor effect potentiator for enhancing antitumor activity of an antitumor agent comprising tegafur in a therapeutically effective amount, gimeracil in an amount effective for enhancing an antitumor effect, and oteracil potassium in an amount effective for inhibiting a side effect, the antitumor effect potentiator comprising at least one member selected from the group consisting of folinic acid and pharmacologically acceptable salts thereof in an amount effective for enhancing an antitumor effect; an antitumor agent comprising, as active ingredients, tegafur in a therapeutically effective amount, gimeracil in an amount effective for enhancing an antitumor effect, oteracil potassium in an amount effective for inhibiting a side effect, and at least one member selected from the group consisting of folinic acid and pharmacologically acceptable salts thereof in an amount effective for enhancing an antitumor effect; a method for enhancing an antitumor effect of an antitumor agenType: ApplicationFiled: March 11, 2004Publication date: June 1, 2006Applicant: Taiho Pharmaceutical Co., Ltd.Inventors: Junji Uchida, Koyo Shudo
-
Patent number: 6696956Abstract: An emergency dispatching system which can reduce the occurrence of false reports, reliably send the first report to relatives or the like in an emergency, and automatically detect even the occurrence of an internal danger.Type: GrantFiled: November 6, 2001Date of Patent: February 24, 2004Inventors: Junji Uchida, Kyoko Uchida
-
Patent number: 5420117Abstract: This invention provides a 5-substituted uridine derivative of the formula ##STR1## wherein X is F or CF.sub.3, R.sub.1 and R.sub.2 each represent a group --OSi--(R.sub.4)(R.sub.5)(R.sub.6) (wherein R.sub.4, R.sub.5 and R.sub.6 represent C.sub.1 -C.sub.10 alkyl or the like), OH, aminoacyloxy group wherein the amino group may be substituted with lower alkyl group or carboxylalkylcarbonyloxy group, R.sub.3 is a group --OSi(R.sub.4)(R.sub.5)(R.sub.6), H, OH, aminoacyloxy group wherein the amino group may be substituted with lower alkyl group, or carboxylalkylcarbonyloxy group, and at least one of R.sub.1, R.sub.2 and R.sub.3 is a group --OSi--(R.sub.4)(R.sub.5)(R.sub.6), with the proviso that when X is fluorine atom, R.sub.3 is not hydrogen, and an intermediate for the preparation thereof, preparation processes of the derivative and anti-tumor agent containing the derivative as an active ingredient.Type: GrantFiled: October 19, 1992Date of Patent: May 30, 1995Assignee: Taiho Pharmaceutical Co., Ltd.Inventors: Tadafumi Terada, Katsuhiko Fujimoto, Junichi Yamashita, Mitsugi Yasumoto, Setsuo Takeda, Junji Uchida, Konstanty Wierzba, Yuji Yamada