Patents by Inventor Junjie DONG
Junjie DONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250099586Abstract: Provided is a set of viral vectors, comprising: a first viral vector that carries a first nucleic acid molecule encoding an envelope protein, and a second viral vector that carries a second nucleic acid molecule encoding a fusion protein, the fusion protein comprising: a single-chain antibody capable of binding to CD28 or CD3, and a C-terminal domain, comprising a transmembrane region and an intracellular region, of the envelope protein. The C terminal of the single-chain antibody is connected to the N terminal of the C-terminal domain of the envelope protein, and the envelope protein and the fusion protein are in a non-fusion form. Also provided are a method for obtaining a lentivirus and an obtained lentivirus, a method for introducing a lentivirus into an unactivated T lymphocyte, a method for expressing a target gene, a method for obtaining a CAR-T cell and an obtained CAR-T cell, a pharmaceutical composition, and a use thereof.Type: ApplicationFiled: January 16, 2023Publication date: March 27, 2025Applicant: SUNSHINE LAKE PHARMA CO., LTD.Inventors: Xiaodan YANG, Shiyou CHEN, Xiuqin ZHU, Linsheng LI, Junji DONG, Guanghui ZHAO, Lijia LI, Xiaofeng CHEN, Wenjia LI
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Publication number: 20250002574Abstract: An antibody or an antigen-binding fragment thereof capable of specifically recognizing IL-11. The antibody includes heavy chain variable region CDRs as shown in SEQ ID NOs: 4-6, light chain variable region CDRs as shown in SEQ ID NOs: 37-39, heavy chain framework regions as shown in SEQ ID NOs: 67-70, and light chain framework regions as shown in SEQ ID NOs: 71-74, respectively. The antibody has low immunogenicity and can specifically target and bind to IL-11, so as to block binding of IL-11 to an IL-11 receptor.Type: ApplicationFiled: August 11, 2022Publication date: January 2, 2025Applicant: SUNSHINE LAKE PHARMA CO., LTD.Inventors: Jiatao ZHOU, Cangsha CHEN, Yincai WANG, Miaoxing JIE, Junji DONG, Wenjia LI
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Publication number: 20240076690Abstract: A group of viral vectors including: first viral vector, wherein first viral vector carries first nucleic acid molecule, and the first nucleic acid molecule encodes envelope protein; second viral vector, wherein second viral vector carries second nucleic acid molecule, the second nucleic acid molecule encodes fusion protein, the fusion protein includes single-chain antibody and C-terminal domain of envelope protein, the C-terminal domain of envelope protein includes transmembrane region and intracellular region of envelope protein, the C-terminus of single-chain antibody connects with N-terminus of C-terminal domain of envelope protein, the single-chain antibody targets a specific antigen; first nucleic acid molecule and second nucleic acid molecule are arranged to express envelope protein and fusion protein, and the envelope protein and the fusion protein are in non-fusion form.Type: ApplicationFiled: September 29, 2021Publication date: March 7, 2024Applicant: SUNSHINE LAKE PHARMA CO., LTD.Inventors: Xiaodan YANG, Shiyou CHEN, Xiuqin ZHU, Junji DONG, Xiaofeng CHEN, Wenjia LI
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Publication number: 20230357411Abstract: A humanized antibody or antigen-binding fragment thereof capable of specifically recognizing TrkA and uses thereof. The antibody includes a heavy chain variable region with an amino acid sequence shown in any one of SEQ ID NO: 2-8, and a light chain variable region with an amino acid sequence shown in any one of SEQ ID NO: 10-13. The above-mentioned antibody according to the embodiments of the present invention can specifically target and bind to the TrkA receptor and block the binding of NGF and TrkA.Type: ApplicationFiled: November 18, 2021Publication date: November 9, 2023Applicant: SUNSHINE LAKE PHARMA CO., LTD.Inventors: Zhiheng REN, Junji DONG, Zhuandi HE, Kezhu WANG, Jielian LU, Shushan LIN, Liang LIU, Xiang LI, Kuo ZHANG, Yan JIANG, Xiaoping LI, Xiaofeng CHEN, Wenjia LI
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Patent number: 11729305Abstract: A method for constructing a novel device includes: acquiring function models corresponding to at least one physical device, each of the function models corresponding to a function of one physical device; acquiring a construction rule for a target novel device; and constructing the target novel device on the basis of at least one of the function models according to the construction rule. As such, the novel model device can be obtained by acquiring the function models from the physical device and constructing the function models, such that functions achievable by the physical device are extended.Type: GrantFiled: July 16, 2020Date of Patent: August 15, 2023Assignee: BEIJING XIAOMI MOBILE SOFTWARE CO., LTD.Inventors: Bin Guo, Junjie Dong, Zhao Zhang, Yan Xu
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Publication number: 20230235049Abstract: An invention provides a chimeric antigen receptor. The chimeric antigen receptor includes an extracellular domain including a heavy chain variable region, a light chain variable region of a single chain antibody fragment and CD8 hinge region; a transmembrane domain including an immune co-stimulator transmembrane domain; and an intracellular domain including an immune co-stimulator intracellular segment and CD3? chain. According to the embodiments of the invention, the chimeric antigen receptor can specifically recognize the tumor cells expressing the specific antigen and achieve the specific killing effect against the tumor cells expressing the high specific antigen.Type: ApplicationFiled: August 11, 2020Publication date: July 27, 2023Applicant: SUNSHINE LAKE PHARMA CO., LTD.Inventors: Chao CHEN, Junji DONG, Tingting YU, Yi ZENG, Le XU, Xufang WANG, Zhiguang LI, Shaoyan LI, Qunrui YE, Xiaofeng CHEN, Wenjia LI
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Patent number: 11604849Abstract: A rendering method, rendering apparatus implementing said rendering method, an electronic device implementing said rendering method, and a storage medium implementing said rendering method includes: obtaining data of a page to be processed; extracting a plurality of page elements from the data of the page to be processed; obtaining content and a plurality of attributes of each page element of the plurality of page elements; generating a plurality of rendering object sets, each rendering object set corresponding to each page element based on the content and the plurality of attributes of the respective page element, each rendering object set including a plurality of rendering objects; generating a rendering tree based on a plurality of rendering object sets corresponding respectively to the plurality of page elements; and performing a rendering process based on the rendering tree.Type: GrantFiled: July 23, 2021Date of Patent: March 14, 2023Assignee: BEIJING XIAOMI MOBILE SOFTWARE CO., LTD.Inventors: Baoqiu Cui, Junjie Dong, Hua Wu
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Publication number: 20220237256Abstract: A rendering method, rendering apparatus implementing said rendering method, an electronic device implementing said rendering method, and a storage medium implementing said rendering method includes: obtaining data of a page to be processed; extracting a plurality of page elements from the data of the page to be processed; obtaining content and a plurality of attributes of each page element of the plurality of page elements; generating a plurality of rendering object sets, each rendering object set corresponding to each page element based on the content and the plurality of attributes of the respective page element, each rendering object set including a plurality of rendering objects; generating a rendering tree based on a plurality of rendering object sets corresponding respectively to the plurality of page elements; and performing a rendering process based on the rendering tree.Type: ApplicationFiled: July 23, 2021Publication date: July 28, 2022Inventors: Baoqiu CUI, Junjie DONG, Hua WU
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Publication number: 20220204630Abstract: An antibody or an antigen-binding fragment thereof is capable of specifically recognizing TrkA and uses thereof. The antibody contains a CDR sequence selected from at least one of the following or an amino acid sequence having at least 95% identity with it: heavy chain variable region CDR sequences: SEQ ID NO: 1˜27, light chain variable region CDR sequences: SEQ IN NO: 28˜54. The above antibody can specifically targeted-bind to the TrkA receptor and block the binding of NGF to TrkA.Type: ApplicationFiled: May 28, 2020Publication date: June 30, 2022Applicant: SUNSHINE LAKE PHARMA CO., LTD.Inventors: Chao CHEN, Zhiheng REN, Zhuandi HE, Jielian LU, Shushan LIN, Tingting YU, Xiling WEI, Xufang WANG, Le XU, Junji DONG, Xiang LI, Kuo ZHANG, Xueyao YANG, Linfeng GUO, Xiaoping LI, Xiaofeng CHEN, Wenjia LI
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Patent number: 11153278Abstract: A method for information interaction includes: when an access request sent by a webpage to a preset domain name is received by a browser component, resolving the preset domain name into a designated access address, the access request being sent by the webpage when the webpage is required to interact with an operating system of a terminal, and the designated access address being an access address that has not been occupied; sending the access request to the designated access address as a destination address; and when a firewall detects that the destination address of the access request is the designated access address, redirecting the access request to a local web service, the local web service being configured for information interaction with the operating system of the terminal.Type: GrantFiled: March 13, 2019Date of Patent: October 19, 2021Assignee: BEIJING XIAOMI MOBILE SOFTWARE CO., LTD.Inventors: Junjie Dong, Shun Chen, Hongguang Dong
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Publication number: 20210151204Abstract: A method for constructing a novel device includes: acquiring function models corresponding to at least one physical device, each of the function models corresponding to a function of one physical device; acquiring a construction rule for a target novel device; and constructing the target novel device on the basis of at least one of the function models according to the construction rule. As such, the novel model device can be obtained by acquiring the function models from the physical device and constructing the function models, such that functions achievable by the physical device are extended.Type: ApplicationFiled: July 16, 2020Publication date: May 20, 2021Applicant: BEIJING XIAOMI MOBILE SOFTWARE CO., LTD.Inventors: Bin GUO, Junjie DONG, Zhao ZHANG, Yan XU
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Patent number: 10824491Abstract: A system information transmitting method and apparatus, and a computer-readable storage medium are provided. The method includes receiving, at a terminal, a system call instruction sent by a browser, acquiring, at the terminal, target system information according to the system call instruction, dividing, at the terminal, the target system information into at least one data set, obtaining, at the terminal, encoded pseudo-touch event information by encoding the at least one data segment in the target system information according to a positional relationship of respective touch points in a simulated pseudo-touch event in a touch plane, and transmitting, from the terminal, as an input parameter of the target script, the encoded pseudo-touch event information to the target script through the browser.Type: GrantFiled: March 13, 2020Date of Patent: November 3, 2020Assignee: Beijing Xiaomi Mobile Software Co., Ltd.Inventors: Junjie Dong, Shun Chen, Hongguang Dong
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Patent number: 10817355Abstract: Provided is an apparatus for communication between a webpage and an operating system. The apparatus includes memory storing a first software for an operating system and a second software for a web browser. The apparatus also includes processing circuitry that executes the first software to provide the operating system including a clipboard and executes the second software to cause the web browser to access a web page. Further, a software (the first software or the second software) executed by the processing circuitry detects a message that is buffered in a clipboard provided by the operating system, and determines whether the message is in a preset format that is indicative of the software executed by the processing circuitry being a destination of the message. The software executed by the processing circuitry then processes the message when the message is in the preset format.Type: GrantFiled: March 26, 2019Date of Patent: October 27, 2020Assignee: BEIJING XIAOMI MOBILE SOFTWARE CO., LTD.Inventors: Shun Chen, Hongguang Dong, Junjie Dong
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Publication number: 20200293390Abstract: A system information transmitting method and apparatus, and a computer-readable storage medium are provided. The method includes receiving, at a terminal, a system call instruction sent by a browser, acquiring, at the terminal, target system information according to the system call instruction, dividing, at the terminal, the target system information into at least one data set, obtaining, at the terminal, encoded pseudo-touch event information by encoding the at least one data segment in the target system information according to a positional relationship of respective touch points in a simulated pseudo-touch event in a touch plane, and transmitting, from the terminal, as an input parameter of the target script, the encoded pseudo-touch event information to the target script through the browser.Type: ApplicationFiled: March 13, 2020Publication date: September 17, 2020Applicant: BEIJING XIAOMI MOBILE SOFTWARE CO., LTD.Inventors: Junjie DONG, Shun CHEN, Hongguang DONG
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Publication number: 20190311017Abstract: The present disclosure relates to an information interaction method, and relates to the field of mobile terminal technologies. The method includes: receiving a webpage request sent by a browsing application in a mobile terminal, wherein the webpage request is used to request information required for a webpage to be displayed in the browsing application from an operating system of the mobile terminal; sending the webpage request to the operating system through a long connection with the operating system of the mobile terminal; receiving a system response to the webpage request, which is sent from the operating system, and sending the system response to the browsing application. The information interaction between the webpage and the operating system of the mobile terminal is no longer limited by the browsing application.Type: ApplicationFiled: April 5, 2019Publication date: October 10, 2019Applicant: BEIJING XIAOMI MOBILE SOFTWARE CO., LTD.Inventors: Junjie DONG, Shun CHEN, Hongguang DONG
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Publication number: 20190306122Abstract: A method for information interaction includes: when an access request sent by a webpage to a preset domain name is received by a browser component, resolving the preset domain name into a designated access address, the access request being sent by the webpage when the webpage is required to interact with an operating system of a terminal, and the designated access address being an access address that has not been occupied; sending the access request to the designated access address as a destination address; and when a firewall detects that the destination address of the access request is the designated access address, redirecting the access request to a local web service, the local web service being configured for information interaction with the operating system of the terminal.Type: ApplicationFiled: March 13, 2019Publication date: October 3, 2019Applicant: BEIJING XIAOMI MOBILE SOFTWARE CO., LTD.Inventors: Junjie Dong, Shun Chen, Hongguang Dong
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Publication number: 20190303225Abstract: Aspects of the disclosure provide methods and apparatuses for communication between a webpage and an operating system. For example, an apparatus includes memory storing a first software for an operating system and a second software for a web browser. The apparatus also includes processing circuitry that executes the first software to provide the operating system including a clipboard and executes the second software to cause the web browser to access a web page. Further, a software (the first software or the second software) executed by the processing circuitry detects a message that is buffered in a clipboard provided by the operating system, and determines whether the message is in a preset format that is indicative of the software executed by the processing circuitry being a destination of the message. The software executed by the processing circuitry then processes the message when the message is in the preset format.Type: ApplicationFiled: March 26, 2019Publication date: October 3, 2019Applicant: BEIJING XIAOMI MOBILE SOFTWARE CO., LTD.Inventors: Shun CHEN, Hongguang DONG, Junjie DONG
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Patent number: 10296191Abstract: A method for changing a display background is disclosed. The method may be implemented by a server. The method may comprise acquiring a user preference label set of a current user and a background label set of each candidate background; matching the current user with each candidate background based on the acquired user preference label set and the acquired background label set to obtain a match result; selecting one or more recommended backgrounds for the current user based on the match result; and pushing the selected one or more recommended backgrounds to a mobile terminal of the current user.Type: GrantFiled: August 22, 2016Date of Patent: May 21, 2019Assignee: Xiaomi Inc.Inventor: Junjie Dong
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Patent number: 10108323Abstract: A method for drawing a graphical user interface (GUI) is disclosed. The method may be implemented by a terminal. The method may comprise receiving an instruction for drawing a GUI; determining attribute data of each of graphic elements in a scalable vector graphic (SVG) document according to the received instruction, the graphic elements corresponding to the GUI; and drawing the GUI according to the determined attribute data.Type: GrantFiled: July 14, 2016Date of Patent: October 23, 2018Assignee: Xiaomi Inc.Inventor: Junjie Dong
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Publication number: 20170139574Abstract: A method for drawing a graphical user interface (GUI) is disclosed. The method may be implemented by a terminal. The method may comprise receiving an instruction for drawing a GUI; determining attribute data of each of graphic elements in a scalable vector graphic (SVG) document according to the received instruction, the graphic elements corresponding to the GUI; and drawing the GUI according to the determined attribute data.Type: ApplicationFiled: July 14, 2016Publication date: May 18, 2017Inventor: Junjie DONG