Abstract: A sealant of a liquid crystal panel and a modification method therefor are disclosed. The sealant contains modified epoxy resins which is formed by a cross-linking and curing reaction between isocyanate-terminated tri-functional monomers and epoxy monomers. The modified epoxy resin has a plurality of trifurcate cross-linking long-chain structures, and each of the trifurcate cross-linking long-chain structures has three isocyanate groups, each of which is flexibly linked to one or more molecular groups of epoxy resin. The modified epoxy resin can enhance the adhesion property of the epoxy resin with surfaces of glass substrates and the stress-and-cracking resistance of the epoxy resin, while it can efficiently prevent from the miscible material problem between the epoxy resin and the liquid crystal material, so as to relatively lower the possibility of contaminating the liquid crystal material.