Abstract: A preparation method for a universal CAR-T cell, and an use of a universal CAR-T cell. When universal CAR-T is prepared, an RNP complex comprises an RNP complex composed of a Cas9 protein and sgRNA; and the SgRNA is SgRNA of CD4 and/or sgRNA of CD8. ?he CD4 gene and/or CD8 gene of the universal CAR-T cell or a T cell are/is knocked out and/or inactivated. The CAR-T cell expresses CD44 and/or CD62L, so that the activity of the CAR-T cell can be enhanced, the effectiveness of CAR-T is enhanced, the CAR-T cell has a better phenotype and lower exhaustion expression, and the killing of the CAR-T cell against a tumor target cell is improved, and thus, the CAR-T cell can be used for targeted therapy of tumors and can be used for allogenic CAR-T therapy.

Abstract: Embodiments of the present invention provide an optical structure, an optical coupling method, and a photonic integrated circuit chip. The optical structure includes: two optical coupling structures with different structures, that is, a first optical coupling structure and a second optical coupling structure. The first optical coupling structure includes a first optical transmission structure, and a first coupling port and a second coupling port both connected to the first optical transmission structure. The second optical coupling structure includes a second optical transmission structure, and a third coupling port and a photoelectric conversion structure both connected to the second optical transmission structure. When optical signals are provided in different methods or optical coupling is performed in different scenarios, optical signal coupling can be realized by using optical coupling structures of different structures in the abovementioned optical structure.

Abstract: A secure element for a device includes an operative system the secure element including a first security applet configure to communicate with the device operative system, wherein the first security applet is configure to accept any first external application, after performing a key registration, as a local administrator application for some first data provided by the first external application, so that no other external application may access the first data without a permission of the first external application. The disclosure also provides a telecommunications device and a method of management of secure information in such a secure element.

Abstract: A wiring component with temperature sensor includes an electric wire, a temperature sensor including a detection unit configured to detect temperature of the electric wire and a plurality of lead wires, and a plurality of connector pins respectively connected to the plurality of lead wires. The electric wire, the temperature sensor and the plurality of connector pins are collectively held by a holder made of a resin. The holder includes a connector housing member configured to hold the plurality of connector pins and a molded resin member covering a portion of the connector housing member.

Abstract: Provided is a logistics palletizing system.

Abstract: Provided is a stator of a dynamo-electric machine capable of sufficiently securing the strength of a welding portion of a winding and a coil of a power distribution member by a required minimum configuration, without affecting the insulation coating thickness of an entire end portion. The stator of the dynamo-electric machine of the present invention includes a stator core, a winding wound around the stator core, a power distribution member having a coil in which one end is connected to the winding and the other end is connected to a power supply device, and an insulating film coating at least one end portion of the winding. The stator has a fixing portion fixing the winding and the coil of the power distribution member.

Abstract: A solenoid valve with a hard seal structure includes a valve body having a fluid passage and an accommodating cavity, and a valve assembly mounted inside the accommodating cavity. The valve assembly includes a fluid inlet seat, a valve core cooperating with the fluid inlet seat, and a driving mechanism for driving reciprocating motion of the valve core. The fluid inlet seat has a guide hole that allows the value core to stretch therein, a middle section of the fluid inlet seat has fluid inlet holes, and a lower section of the fluid inlet seat has a valve core fluid passage and a fluid passage slant located at the valve core fluid passage. The valve core includes a bigger-diameter section, a slant section, a smaller-diameter section and a valve core end slant sequentially arranged from up to down.

Abstract: A solenoid valve with a hard seal structure includes a valve body having a fluid passage and an accommodating cavity, and a valve assembly mounted inside the accommodating cavity. The valve assembly includes a fluid inlet seat, a valve core cooperating with the fluid inlet seat, and a driving mechanism for driving reciprocating motion of the valve core. The fluid inlet seat has a guide hole that allows the value core to stretch therein, a middle section of the fluid inlet seat of fluid inlet holes, and a lower section of the fluid inlet seat has a valve core fluid passage and a fluid passage slant located at the valve core fluid passage. The valve core includes a bigger-diameter section, a slant section, a smaller-diameter section and a valve core end slant sequentially arranged from up to down.

Abstract: A wiring component with temperature sensor includes an electric wire, a temperature sensor including a detection unit configured to detect temperature of the electric wire and a plurality of lead wires, and a plurality of connector pins respectively connected to the plurality of lead wires. The electric wire, the temperature sensor and the plurality of connector pins are collectively held by a holder made of a resin. The holder includes a connector housing member configured to hold the plurality of connector pins and a molded resin member covering a portion of the connector housing member.

Abstract: A piping joint connects a resin tube to a connection pipe having a protrusion formed on an outer peripheral surface of a distal end portion of the connection pipe. The piping joint includes a housing press-fitted into the resin tube and an elastically extendable and contractible seal member into which the connection pipe is inserted such that sealing is performed between the connection pipe and the seal member. The housing has a first housing portion positioned in one end portion and having an outer peripheral surface side press-fitted into the resin tube and a second housing portion positioned in the other end portion. The seal member has a first seal portion inserted on an inner peripheral surface side of the second housing portion.

Abstract: A piping joint connects a resin tube to a connection pipe having a protrusion formed on an outer peripheral surface of a distal end portion of the connection pipe. The piping joint includes a housing press-fitted into the resin tube and an elastically extendable and contractible seal member into which the connection pipe is inserted such that sealing is performed between the connection pipe and the seal member. The housing has a first housing portion positioned in one end portion and having an outer peripheral surface side press-fitted into the resin tube and a second housing portion positioned in the other end portion. The seal member has a first seal portion inserted on an inner peripheral surface side of the second housing portion.

Abstract: An emulsion composition, methods of softening fibrous structures using the same, and fibrous substrate treated therewith. The composition comprising: (A) 0.01 to less than 25.0 parts by weight of a diorganopolysiloxane; (B) 0.01 to less than 20.0 parts by weight of softening agents; (C) 8.0 to 60.0 parts by weight of water; and (D) 20.0 to 90.0 parts by weight of water-soluble monovalent or polyvalent alcohols, wherein the continuous phase of said emulsion composition is an aqueous solution consisting of said (C) water and said (D) water-soluble monovalent or polyvalent alcohols in the ratio of from 1:0.5 to 1:10, and total content of said component (C) and (D) is in the rage of 30.0 and 98.0 parts by weight of said emulsion composition.