Patents by Inventor Junko TOMIZUKA

Junko TOMIZUKA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing purified platelets, method for producing platelet product, method for producing blood product, platelet preserving solution, platelet preserving agent, and method for preserving platelets
    Patent number: 11773374
    Abstract: Provided is a method for producing platelets, in which damage to platelets is suppressed compared with a method in which platelets are separated using a filter from a megakaryocyte culture, and then the platelets are concentrated using a hollow fiber membrane and are further washed using the hollow fiber membrane, and purified platelets can be produced in a shorter period of time compared with the time that is taken to perform the above-described method so as to reduce damage to platelets. The method for producing purified platelets of the present invention includes a concentrating step of concentrating a megakaryocyte culture, and a centrifuging step of centrifuging platelets from an obtained concentrate.
    Type: Grant
    Filed: September 19, 2018
    Date of Patent: October 3, 2023
    Assignee: MEGAKARYON CORPORATION
    Inventors: Hiroya Takahara, Junko Tomizuka, Haruki Okamoto, Hidenori Hirose
  • STORAGE LIQUID FOR MAMMALIAN CELLS
    Publication number: 20220145235
    Abstract: An object of the present invention is to provide a novel preservation solution for preserving mammalian cells over a long period of time in a non-frozen state. Ascorbic acid and/or niacin is added to an isotonic solution to prepare a preservation solution. The preservation solution is mixed with platelets and preserved under shaking. Decrease in the functions and viability of the platelets can thereby be suppressed for at least 10 days. Alternatively, the aforementioned preservation solution is mixed with mesenchymal stem cells, megakaryocytes, or T cells and preserved in a non-frozen state. Decrease in the functions and viability of these cells can thereby be suppressed for at least several days to several tens of days.
    Type: Application
    Filed: March 13, 2020
    Publication date: May 12, 2022
    Applicants: MEGAKARYON CORPORATION, OTSUKA PHARMACEUTICAL FACTORY, INC.
    Inventors: Junko TOMIZUKA, Tomohiro SHIGEMORI, Natsuki WATANABE, Taichi TAKENAWA, Chikage SHIRAKAWA, Masuhiro NISHIMURA, Yasutaka FUJITA, Osamu SAWAMOTO
  • METHOD FOR PRODUCING PURIFIED PLATELETS, METHOD FOR PRODUCING PLATELET PRODUCT, METHOD FOR PRODUCING BLOOD PRODUCT, PLATELET PRESERVING SOLUTION, PLATELET PRESERVING AGENT, AND METHOD FOR PRESERVING PLATELETS
    Publication number: 20200216809
    Abstract: Provided is a method for producing platelets, in which damage to platelets is suppressed compared with a method in which platelets are separated using a filter from a megakaryocyte culture, and then the platelets are concentrated using a hollow fiber membrane and are further washed using the hollow fiber membrane, and purified platelets can be produced in a shorter period of time compared with the time that is taken to perform the above-described method so as to reduce damage to platelets. The method for producing purified platelets of the present invention includes a concentrating step of concentrating a megakaryocyte culture, and a centrifuging step of centrifuging platelets from an obtained concentrate.
    Type: Application
    Filed: September 19, 2018
    Publication date: July 9, 2020
    Inventors: Hiroya TAKAHARA, Junko TOMIZUKA